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James E. Darnell

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American biologist

James E. Darnell
James E. Darnell receiving the 2002 National Medal of Science
Born	(1930-09-09)September 9, 1930 (age 94) Columbus,Mississippi
Citizenship	United States
Alma mater	University of Mississippi(B.A., 1951) Washington University School of Medicine in St. Louis(M.D., 1955)^[4]
Known for	Original discovery of RNA processing ineukaryotes. Determined how extracellular proteins (cytokines) stimulates nuclear gene expression.
Awards	Albany Medical Center Prize(2012)^[1] Albert Lasker Special Achievement Award(2002) National Medal of Science(2002)^[2] E.B. Wilson Medal(1998) Canada Gairdner International Award(1986)^[3]
Scientific career
Fields	Biochemistry Molecular Biology Developmental Biology
Institutions	The Rockefeller University Massachusetts Institute of Technology Albert Einstein College of Medicine Columbia University

James Edwin Darnell Jr. (born September 9, 1930,Columbus, Mississippi)^[5] is an American biologist who made significant contributions to RNA processing and cytokine signaling and is author of the cell biology textbookMolecular Cell Biology.

In 2004, he was elected a foreign member of theRoyal Swedish Academy of Sciences. He became a member of theAmerican Philosophical Society in 2013.^[6]

Since 2013, Darnell has been listed on the Advisory Council of theNational Center for Science Education.^[7]

He is married to Norwegian former model and dress shop owner Kristin Holby, known as "Clotilde", whose daughter Phoebe, a financial analyst, is married to businessmanDivya Narendra.^[8]

Awards

[edit]

1999Dickson Prize
1999 Cancer Research InstituteWilliam B. Coley Award
2002National Medal of Science^[9]
2002Albert Lasker Special Achievement Award
2010Hope Funds Award in Basic Research
2012Albany Medical Center Prize

References

[edit]

^"'Towering Figures' in Cell Research to Share Albany Medical Center Prize".Albany Medical Center. Retrieved11 February 2015.
^"President's National Medal of Science, James E. Darnell".National Science Foundation. Retrieved25 November 2014.
^"Canada Gairdner International Award Recipient James E. Darnell MD".Gairdner Foundation. Retrieved25 November 2014.
^Strong, Colby (June 11, 1990). "People: James E. Darnell, Jr., Is Appointed Chief Academic Officer At Rockefeller University".The Scientist.4 (12).
^Laureates of the 2002 National Medal of Science
^"APS Member History".search.amphilsoc.org. Retrieved2021-03-17.
^"Advisory Council".ncse.com.National Center for Science Education. 15 July 2008. Archived fromthe original on 2013-08-10. Retrieved2018-10-30.
^Seymour, Lesley Jane (29 July 2007)."Swap Those Jeans for a Dress, Soccer Mom".The New York Times.
^National Science Foundation - The President's National Medal of Science

External links

[edit]

"Laboratory of Molecular Cell Biology (James Darnell's Lab at The Rockefeller University".The Rockefeller University. Retrieved12 February 2015.

United States National Medal of Science laureates

Behavioral and social science

1960s	1964 Neal Elgar Miller
1980s	1986 Herbert A. Simon 1987 Anne Anastasi George J. Stigler 1988 Milton Friedman
1990s	1990 Leonid Hurwicz Patrick Suppes 1991 George A. Miller 1992 Eleanor J. Gibson 1994 Robert K. Merton 1995 Roger N. Shepard 1996 Paul Samuelson 1997 William K. Estes 1998 William Julius Wilson 1999 Robert M. Solow
2000s	2000 Gary Becker 2003 R. Duncan Luce 2004 Kenneth Arrow 2005 Gordon H. Bower 2008 Michael I. Posner 2009 Mortimer Mishkin
2010s	2011 Anne Treisman 2014 Robert Axelrod 2015 Albert Bandura
2020s	2023 Huda Akil Shelley E. Taylor 2025 Larry Bartels

Biological sciences

1960s	1963 C. B. van Niel 1964 Theodosius Dobzhansky Marshall W. Nirenberg 1965 Francis P. Rous George G. Simpson Donald D. Van Slyke 1966 Edward F. Knipling Fritz Albert Lipmann William C. Rose Sewall Wright 1967 Kenneth S. Cole Harry F. Harlow Michael Heidelberger Alfred H. Sturtevant 1968 Horace Barker Bernard B. Brodie Detlev W. Bronk Jay Lush Burrhus Frederic Skinner 1969 Robert Huebner Ernst Mayr
1970s	1970 Barbara McClintock Albert B. Sabin 1973 Daniel I. Arnon Earl W. Sutherland Jr. 1974 Britton Chance Erwin Chargaff James V. Neel James Augustine Shannon 1975 Hallowell Davis Paul Gyorgy Sterling B. Hendricks Orville Alvin Vogel 1976 Roger Guillemin Keith Roberts Porter Efraim Racker E. O. Wilson 1979 Robert H. Burris Elizabeth C. Crosby Arthur Kornberg Severo Ochoa Earl Reece Stadtman George Ledyard Stebbins Paul Alfred Weiss
1980s	1981 Philip Handler 1982 Seymour Benzer Glenn W. Burton Mildred Cohn 1983 Howard L. Bachrach Paul Berg Wendell L. Roelofs Berta Scharrer 1986 Stanley Cohen Donald A. Henderson Vernon B. Mountcastle George Emil Palade Joan A. Steitz 1987 Michael E. DeBakey Theodor O. Diener Harry Eagle Har Gobind Khorana Rita Levi-Montalcini 1988 Michael S. Brown Stanley Norman Cohen Joseph L. Goldstein Maurice R. Hilleman Eric R. Kandel Rosalyn Sussman Yalow 1989 Katherine Esau Viktor Hamburger Philip Leder Joshua Lederberg Roger W. Sperry Harland G. Wood
1990s	1990 Baruj Benacerraf Herbert W. Boyer Daniel E. Koshland Jr. Edward B. Lewis David G. Nathan E. Donnall Thomas 1991 Mary Ellen Avery G. Evelyn Hutchinson Elvin A. Kabat Robert W. Kates Salvador Luria Paul A. Marks Folke K. Skoog Paul C. Zamecnik 1992 Maxine Singer Howard Martin Temin 1993 Daniel Nathans Salome G. Waelsch 1994 Thomas Eisner Elizabeth F. Neufeld 1995 Alexander Rich 1996 Ruth Patrick 1997 James Watson Robert A. Weinberg 1998 Bruce Ames Janet Rowley 1999 David Baltimore Jared Diamond Lynn Margulis
2000s	2000 Nancy C. Andreasen Peter H. Raven Carl Woese 2001 Francisco J. Ayala George F. Bass Mario R. Capecchi Ann Graybiel Gene E. Likens Victor A. McKusick Harold Varmus 2002 James E. Darnell Evelyn M. Witkin 2003 J. Michael Bishop Solomon H. Snyder Charles Yanofsky 2004 Norman E. Borlaug Phillip A. Sharp Thomas E. Starzl 2005 Anthony Fauci Torsten N. Wiesel 2006 Rita R. Colwell Nina Fedoroff Lubert Stryer 2007 Robert J. Lefkowitz Bert W. O'Malley 2008 Francis S. Collins Elaine Fuchs J. Craig Venter 2009 Susan L. Lindquist Stanley B. Prusiner
2010s	2010 Ralph L. Brinster Rudolf Jaenisch 2011 Lucy Shapiro Leroy Hood Sallie Chisholm 2012 May Berenbaum Bruce Alberts 2013 Rakesh K. Jain 2014 Stanley Falkow Mary-Claire King Simon Levin
2020s	2023 Gebisa Ejeta Eve Marder Gregory Petsko Sheldon Weinbaum 2025 Bonnie Bassler Angela Belcher Helen Blau Emery N. Brown G. David Tilman Teresa Woodruff

Chemistry

1960s	1964 Roger Adams
1980s	1982 F. Albert Cotton Gilbert Stork 1983 Roald Hoffmann George C. Pimentel Richard N. Zare 1986 Harry B. Gray Yuan Tseh Lee Carl S. Marvel Frank H. Westheimer 1987 William S. Johnson Walter H. Stockmayer Max Tishler 1988 William O. Baker Konrad E. Bloch Elias J. Corey 1989 Richard B. Bernstein Melvin Calvin Rudolph A. Marcus Harden M. McConnell
1990s	1990 Elkan Blout Karl Folkers John D. Roberts 1991 Ronald Breslow Gertrude B. Elion Dudley R. Herschbach Glenn T. Seaborg 1992 Howard E. Simmons Jr. 1993 Donald J. Cram Norman Hackerman 1994 George S. Hammond 1995 Thomas Cech Isabella L. Karle 1996 Norman Davidson 1997 Darleane C. Hoffman Harold S. Johnston 1998 John W. Cahn George M. Whitesides 1999 Stuart A. Rice John Ross Susan Solomon
2000s	2000 John D. Baldeschwieler Ralph F. Hirschmann 2001 Ernest R. Davidson Gábor A. Somorjai 2002 John I. Brauman 2004 Stephen J. Lippard 2005 Tobin J. Marks 2006 Marvin H. Caruthers Peter B. Dervan 2007 Mostafa A. El-Sayed 2008 Joanna Fowler JoAnne Stubbe 2009 Stephen J. Benkovic Marye Anne Fox
2010s	2010 Jacqueline K. Barton Peter J. Stang 2011 Allen J. Bard M. Frederick Hawthorne 2012 Judith P. Klinman Jerrold Meinwald 2013 Geraldine L. Richmond 2014 A. Paul Alivisatos 2025 R. Lawrence Edwards

Engineering sciences

1960s	1962 Theodore von Kármán 1963 Vannevar Bush John Robinson Pierce 1964 Charles S. Draper Othmar H. Ammann 1965 Hugh L. Dryden Clarence L. Johnson Warren K. Lewis 1966 Claude E. Shannon 1967 Edwin H. Land Igor I. Sikorsky 1968 J. Presper Eckert Nathan M. Newmark 1969 Jack St. Clair Kilby
1970s	1970 George E. Mueller 1973 Harold E. Edgerton Richard T. Whitcomb 1974 Rudolf Kompfner Ralph Brazelton Peck Abel Wolman 1975 Manson Benedict William Hayward Pickering Frederick E. Terman Wernher von Braun 1976 Morris Cohen Peter C. Goldmark Erwin Wilhelm Müller 1979 Emmett N. Leith Raymond D. Mindlin Robert N. Noyce Earl R. Parker Simon Ramo
1980s	1982 Edward H. Heinemann Donald L. Katz 1983 Bill Hewlett George Low John G. Trump 1986 Hans Wolfgang Liepmann Tung-Yen Lin Bernard M. Oliver 1987 Robert Byron Bird H. Bolton Seed Ernst Weber 1988 Daniel C. Drucker Willis M. Hawkins George W. Housner 1989 Harry George Drickamer Herbert E. Grier
1990s	1990 Mildred Dresselhaus Nick Holonyak Jr. 1991 George H. Heilmeier Luna B. Leopold H. Guyford Stever 1992 Calvin F. Quate John Roy Whinnery 1993 Alfred Y. Cho 1994 Ray W. Clough 1995 Hermann A. Haus 1996 James L. Flanagan C. Kumar N. Patel 1998 Eli Ruckenstein 1999 Kenneth N. Stevens
2000s	2000 Yuan-Cheng B. Fung 2001 Andreas Acrivos 2002 Leo Beranek 2003 John M. Prausnitz 2004 Edwin N. Lightfoot 2005 Jan D. Achenbach 2006 Robert S. Langer 2007 David J. Wineland 2008 Rudolf E. Kálmán 2009 Amnon Yariv
2010s	2010 Shu Chien 2011 John B. Goodenough 2012 Thomas Kailath
2020s	2023 Subra Suresh 2025 John Dabiri

Mathematical, statistical, and computer sciences

1960s	1963 Norbert Wiener 1964 Solomon Lefschetz H. Marston Morse 1965 Oscar Zariski 1966 John Milnor 1967 Paul Cohen 1968 Jerzy Neyman 1969 William Feller
1970s	1970 Richard Brauer 1973 John Tukey 1974 Kurt Gödel 1975 John W. Backus Shiing-Shen Chern George Dantzig 1976 Kurt Otto Friedrichs Hassler Whitney 1979 Joseph L. Doob Donald E. Knuth
1980s	1982 Marshall H. Stone 1983 Herman Goldstine Isadore Singer 1986 Peter Lax Antoni Zygmund 1987 Raoul Bott Michael Freedman 1988 Ralph E. Gomory Joseph B. Keller 1989 Samuel Karlin Saunders Mac Lane Donald C. Spencer
1990s	1990 George F. Carrier Stephen Cole Kleene John McCarthy 1991 Alberto Calderón 1992 Allen Newell 1993 Martin David Kruskal 1994 John Cocke 1995 Louis Nirenberg 1996 Richard Karp Stephen Smale 1997 Shing-Tung Yau 1998 Cathleen Synge Morawetz 1999 Felix Browder Ronald R. Coifman
2000s	2000 John Griggs Thompson Karen Uhlenbeck 2001 Calyampudi R. Rao Elias M. Stein 2002 James G. Glimm 2003 Carl R. de Boor 2004 Dennis P. Sullivan 2005 Bradley Efron 2006 Hyman Bass 2007 Leonard Kleinrock Andrew J. Viterbi 2009 David B. Mumford
2010s	2010 Richard A. Tapia S. R. Srinivasa Varadhan 2011 Solomon W. Golomb Barry Mazur 2012 Alexandre Chorin David Blackwell 2013 Michael Artin
2020s	2025 Ingrid Daubechies Cynthia Dwork

Physical sciences

1960s	1963 Luis W. Alvarez 1964 Julian Schwinger Harold Urey Robert Burns Woodward 1965 John Bardeen Peter Debye Leon M. Lederman William Rubey 1966 Jacob Bjerknes Subrahmanyan Chandrasekhar Henry Eyring John H. Van Vleck Vladimir K. Zworykin 1967 Jesse Beams Francis Birch Gregory Breit Louis Hammett George Kistiakowsky 1968 Paul Bartlett Herbert Friedman Lars Onsager Eugene Wigner 1969 Herbert C. Brown Wolfgang Panofsky
1970s	1970 Robert H. Dicke Allan R. Sandage John C. Slater John A. Wheeler Saul Winstein 1973 Carl Djerassi Maurice Ewing Arie Jan Haagen-Smit Vladimir Haensel Frederick Seitz Robert Rathbun Wilson 1974 Nicolaas Bloembergen Paul Flory William Alfred Fowler Linus Carl Pauling Kenneth Sanborn Pitzer 1975 Hans A. Bethe Joseph O. Hirschfelder Lewis Sarett Edgar Bright Wilson Chien-Shiung Wu 1976 Samuel Goudsmit Herbert S. Gutowsky Frederick Rossini Verner Suomi Henry Taube George Uhlenbeck 1979 Richard P. Feynman Herman Mark Edward M. Purcell John Sinfelt Lyman Spitzer Victor F. Weisskopf
1980s	1982 Philip W. Anderson Yoichiro Nambu Edward Teller Charles H. Townes 1983 E. Margaret Burbidge Maurice Goldhaber Helmut Landsberg Walter Munk Frederick Reines Bruno B. Rossi J. Robert Schrieffer 1986 Solomon J. Buchsbaum H. Richard Crane Herman Feshbach Robert Hofstadter Chen-Ning Yang 1987 Philip Abelson Walter Elsasser Paul C. Lauterbur George Pake James A. Van Allen 1988 D. Allan Bromley Paul Ching-Wu Chu Walter Kohn Norman Foster Ramsey Jr. Jack Steinberger 1989 Arnold O. Beckman Eugene Parker Robert Sharp Henry Stommel
1990s	1990 Allan M. Cormack Edwin M. McMillan Robert Pound Roger Revelle 1991 Arthur L. Schawlow Ed Stone Steven Weinberg 1992 Eugene M. Shoemaker 1993 Val Fitch Vera Rubin 1994 Albert Overhauser Frank Press 1995 Hans Dehmelt Peter Goldreich 1996 Wallace S. Broecker 1997 Marshall Rosenbluth Martin Schwarzschild George Wetherill 1998 Don L. Anderson John N. Bahcall 1999 James Cronin Leo Kadanoff
2000s	2000 Willis E. Lamb Jeremiah P. Ostriker Gilbert F. White 2001 Marvin L. Cohen Raymond Davis Jr. Charles Keeling 2002 Richard Garwin W. Jason Morgan Edward Witten 2003 G. Brent Dalrymple Riccardo Giacconi 2004 Robert N. Clayton 2005 Ralph A. Alpher Lonnie Thompson 2006 Daniel Kleppner 2007 Fay Ajzenberg-Selove Charles P. Slichter 2008 Berni Alder James E. Gunn 2009 Yakir Aharonov Esther M. Conwell Warren M. Washington
2010s	2011 Sidney Drell Sandra Faber Sylvester James Gates 2012 Burton Richter Sean C. Solomon 2014 Shirley Ann Jackson
2020s	2023 Barry Barish Myriam Sarachik 2025 Richard Alley Wendy Freedman Keivan Stassun

v t e E.B. Wilson Medal recipients
Recipients	Daniel Mazia,George Palade andKeith Porter (1981) Charles Leblond andAlex B. Novikoff (1982) Joseph Gall andHugh Huxley (1983) Harry Eagle andTheodore Puck (1984) Hewson Swift (1985) Gunter Blobel andDavid D. Sabatini (1986) Marilyn Farquhar (1987) Elizabeth Hay (1988) Christian de Duve (1989) Morris Karnovsky (1990) S. Jonathan Singer (1991) Shinya Inoue (1992) Hans Ris (1993) Barbara Gibbons andIan R. Gibbons (1994) Bruce Nicklas (1995) Donald D. Brown (1996) John C. Gerhart (1997) James E. Darnell andSheldon Penman (1998) Edwin Taylor (1999) Walter Neupert andGottfried Schatz (2000) Elizabeth Blackburn (2001) Avram Hershko andAlexander Varshavsky (2002) Marc Kirschner (2003) Thomas D. Pollard (2004) Joan A. Steitz (2005) Joel Rosenbaum (2006) Richard O. Hynes andZena Werb (2007) Martin Chalfie andRoger Tsien (2008) Peter Walter (2009) Stuart Kornfeld,James Rothman, andRandy Schekman (2010) Gary Borisy,J. Richard McIntosh, andJames Spudich (2011) Susan Lindquist (2012) John R. Pringle (2013) William R. Brinkley,John E. Heuser andPeter Satir (2014) Elaine V. Fuchs (2015) Mina Bissell (2016) Franz-Ulrich Hartl andArthur Horwich (2017) Barbara J. Meyer (2018) Peter N. Devreotes (2019) Jennifer Lippincott-Schwartz (2020) Pietro De Camilli (2021)

E.B. Wilson Medal recipients

Recipients

Daniel Mazia,George Palade andKeith Porter (1981)
Charles Leblond andAlex B. Novikoff (1982)
Joseph Gall andHugh Huxley (1983)
Harry Eagle andTheodore Puck (1984)
Hewson Swift (1985)
Gunter Blobel andDavid D. Sabatini (1986)
Marilyn Farquhar (1987)
Elizabeth Hay (1988)
Christian de Duve (1989)
Morris Karnovsky (1990)
S. Jonathan Singer (1991)
Shinya Inoue (1992)
Hans Ris (1993)
Barbara Gibbons andIan R. Gibbons (1994)
Bruce Nicklas (1995)
Donald D. Brown (1996)
John C. Gerhart (1997)
James E. Darnell andSheldon Penman (1998)
Edwin Taylor (1999)
Walter Neupert andGottfried Schatz (2000)
Elizabeth Blackburn (2001)
Avram Hershko andAlexander Varshavsky (2002)
Marc Kirschner (2003)
Thomas D. Pollard (2004)
Joan A. Steitz (2005)
Joel Rosenbaum (2006)
Richard O. Hynes andZena Werb (2007)
Martin Chalfie andRoger Tsien (2008)
Peter Walter (2009)
Stuart Kornfeld,James Rothman, andRandy Schekman (2010)
Gary Borisy,J. Richard McIntosh, andJames Spudich (2011)
Susan Lindquist (2012)
John R. Pringle (2013)
William R. Brinkley,John E. Heuser andPeter Satir (2014)
Elaine V. Fuchs (2015)
Mina Bissell (2016)
Franz-Ulrich Hartl andArthur Horwich (2017)
Barbara J. Meyer (2018)
Peter N. Devreotes (2019)
Jennifer Lippincott-Schwartz (2020)
Pietro De Camilli (2021)

v t e Fellows of theRoyal Society electedin 1996
Fellows	Alf Adams Jan Anderson Jonathan Ashmore David Beach John Michael Brown Chris Dobson Patrick J. Dowling Dianne Edwards Peter Edwards Andrew Fabian Jim Feast Michael Denis Gale David Gubbins Duncan Haldane Thomas Jessell David Lane Martin Geoffrey Low Andrew Lyne Nicholas Manton Francis Patrick McCormick Iain MacIntyre Thomas Meade Stewart Crichton Miller Ian Mark Mills M. S. Narasimhan Linda Partridge Malcolm Peaker John A. Pickett Peter Pusey Martin Roth Christopher Sachrajda Ekhard Salje Tim Shallice George D. W. Smith Edwin Smith David Ian Stuart Grant Robert Sutherland Martin J. Taylor Phillip V. Tobias James Whitelaw
Foreign	James E. Darnell Jacques-Louis Lions Vernon Benjamin Mountcastle James R. Rice Michael Rossmann Martin Schwarzschild

Fellows of theRoyal Society electedin 1996

Fellows

Foreign

Authority control databases
International	ISNI VIAF FAST WorldCat
National	Germany United States France BnF data Japan Czech Republic Netherlands Norway Korea Poland Israel
Academics	CiNii Scopus
Other	IdRef SNAC

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