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| Routes of administration | Oral |
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| Formula | C11H14N2O |
| Molar mass | 190.246 g·mol−1 |
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Indantadol (CHF-3381,V-3381) is adrug which was formerly being investigated as ananticonvulsant andneuroprotective and is now under development for the treatment ofneuropathic pain andchronic cough inEurope byVernalis andChiesi.[1][2][3][4][5][6][7][8] It acts as acompetitive,reversible, and non-selectivemonoamine oxidase inhibitor,[5][6][9] and as a lowaffinity,non-competitiveNMDA receptor antagonist.[1][2][10] Apilot study of indantadol for chronic cough was initiated in October 2009 and in April 2010 it failed to achieve significant efficacy in neuropathic pain inphase IIbclinical trials.[7][8][11][12]
