 | A request that this article title be changed toFusobacteriati isunder discussion. Pleasedo not move this article until the discussion is closed. |
| Fusobacteria | |
|---|---|
 | |
| Fusobacterium novum in liquid culture | |
Scientific classification | |
| Domain: | Bacteria |
| Kingdom: | Fusobacteriati |
| Phylum: | Fusobacteriota Garrity & Holt 2021[2] |
| Class: | Fusobacteriia Staley & Whitman 2012 |
| Order: | Fusobacteriales Staley & Whitman 2012 |
| Families[1] | |
| Synonyms | |
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Fusobacteriota areobligately anaerobic non-sporeformingGram-negativebacilli. Since the first reports in the late nineteenth century, various names have been applied to these organisms, sometimes with the same name being applied to different species. More recently, not only have there been changes to thenomenclature, but also attempts to differentiate between species which are believed to be either pathogenic or commensal or both. Because of theirasaccharolytic nature, and a general paucity of positive results in routine biochemical tests, laboratory identification of the Fusobacteriota has been difficult. However, the application of novel molecular biological techniques to taxonomy has established a number of new species, together with the subspeciation ofFusobacterium necrophorum andF. nucleatum, and provided new methods for identification. The involvement of Fusobacteriota in a wide spectrum of human infections causing tissue necrosis and septicaemia has long been recognised, and, more recently, their importance in intra-amniotic infections, premature labour and tropical ulcers has been reported.
Since the first reports of Fusobacteriota in the late nineteenth century, the variety of species names has led to some confusion within the generaFusobacterium andLeptotrichia. However, newer methods of investigation have led to a better understanding of the taxonomy, with the description of several new species of Fusobacteriota. Among the new species described areF. ulcerans from tropical ulcers, and several species from the oral cavity. Subspeciation of the important speciesF. necrophorum andF. nucleatum has also been possible. It is probable that the taxonomy of the Fusobacteriota may be further developed in the future.[3]
It is the sole phylum in the kingdomFusobacteriati.[4]
The currently accepted taxonomy is based on theList of Prokaryotic names with Standing in Nomenclature (LSPN)[5] andNational Center for Biotechnology Information (NCBI).[6]
| 16S rRNA basedLTP_10_2024[7][8][9] | 120 marker proteins basedGTDB 09-RS220[10][11][12] | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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New evidence is emerging that this bacterium may cause or be related to human colon cancer. In 2011 investigators reported the presence of Fusobacteriota in colon cancer tissue (Genome Res 2012; 22:292) and a new multicenter study provides evidence that some cases-particularly right-sided might be caused by infection by Fusobacteriota.[13]
