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François Balloux

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Professor of Computational Biology at UCL
François Balloux
EducationUniversity of Lausanne
Scientific career
Fields
Institutions
ThesisGene Flow in Natural Populations: From Panmixia to Speciation (2000)
Websitewww.ucl.ac.uk/biosciences/people/francois-balloux

François Balloux is the director of the UCL Genetics Institute,[1] and a professor ofcomputational biology atUniversity College London.[2]

Early life and education

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Balloux earned a master's degree in 1996 and a doctorate in 2000 from theUniversity of Lausanne. He then completed postdoctoral research at theUniversity of Edinburgh.[2]

Career

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Balloux was an assistant professor at theUniversity of Cambridge, between 2002 and 2007, before taking a position as an associate professor in infectious disease epidemiology atImperial College London. In 2012, Balloux became a full professor atUniversity College London.[2]

Research

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Balloux's research lies at the interface ofgenomics,epidemiology,evolution andecology. The main focus of his work is on the reconstruction of disease outbreaks and epidemics of human and wildlifepathogens,[3][4][5] and the emergence ofantimicrobial resistance.[6][7][8] He has also engaged in research on the emergence and spread of drug resistance intuberculosis,[9][10] andGram-negative bacteria,[11][12] and the distribution of zoonotic pathogens invertebrates.[13]

Balloux participated in curating a dataset ofSARS-CoV-2 genetic samples early on in the pandemic.[14]

References

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  1. ^UCL (2019-02-08)."UCL Genetics Institute".UCL Division of Biosciences. Retrieved2020-04-07.
  2. ^abc"Professor Francois Balloux | UCL Division of Biosciences - UCL - London's Global University".ucl.ac.uk. 13 February 2019. Retrieved2020-03-15.
  3. ^Wang, Ruobing; van Dorp, Lucy; Shaw, Liam P.; Bradley, Phelim; Wang, Qi; Wang, Xiaojuan; Jin, Longyang; Zhang, Qing; Liu, Yuqing; Rieux, Adrien; Dorai-Schneiders, Thamarai (2018-03-21)."The global distribution and spread of the mobilized colistin resistance gene mcr-1".Nature Communications.9 (1): 1179.Bibcode:2018NatCo...9.1179W.doi:10.1038/s41467-018-03205-z.ISSN 2041-1723.PMC 5862964.PMID 29563494.
  4. ^O’Hanlon, Simon J.; Rieux, Adrien; Farrer, Rhys A.; Rosa, Gonçalo M.; Waldman, Bruce; Bataille, Arnaud; Kosch, Tiffany A.; Murray, Kris A.; Brankovics, Balázs; Fumagalli, Matteo; Martin, Michael D. (2018-05-11)."Recent Asian origin of chytrid fungi causing global amphibian declines".Science.360 (6389):621–627.Bibcode:2018Sci...360..621O.doi:10.1126/science.aar1965.ISSN 0036-8075.PMC 6311102.PMID 29748278.
  5. ^Eldholm, Vegard; Pettersson, John H.-O.; Brynildsrud, Ola B.; Kitchen, Andrew; Rasmussen, Erik Michael; Lillebaek, Troels; Rønning, Janne O.; Crudu, Valeriu; Mengshoel, Anne Torunn; Debech, Nadia; Alfsnes, Kristian (2016-11-29)."Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis".Proceedings of the National Academy of Sciences.113 (48):13881–13886.doi:10.1073/pnas.1611283113.ISSN 0027-8424.PMC 5137683.PMID 27872285.
  6. ^Balloux, Francois; Brønstad Brynildsrud, Ola; van Dorp, Lucy; Shaw, Liam P.; Chen, Hongbin; Harris, Kathryn A.; Wang, Hui; Eldholm, Vegard (2018)."From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic".Trends in Microbiology.26 (12):1035–1048.doi:10.1016/j.tim.2018.08.004.PMC 6249990.PMID 30193960.
  7. ^Shaw, Liam P.; Bassam, Hassan; Barnes, Chris P.; Walker, A. Sarah; Klein, Nigel; Balloux, Francois (2019)."Modelling microbiome recovery after antibiotics using a stability landscape framework".The ISME Journal.13 (7):1845–1856.doi:10.1038/s41396-019-0392-1.ISSN 1751-7370.PMC 6591120.PMID 30877283.
  8. ^Eldholm, Vegard; Rieux, Adrien; Monteserin, Johana; Lopez, Julia Montana; Palmero, Domingo; Lopez, Beatriz; Ritacco, Viviana; Didelot, Xavier; Balloux, Francois (2016-08-09). Jit, Mark (ed.)."Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis".eLife.5: e16644.doi:10.7554/eLife.16644.ISSN 2050-084X.PMC 4978521.PMID 27502557.
  9. ^Eldholm, Vegard; Monteserin, Johana; Rieux, Adrien; Lopez, Beatriz; Sobkowiak, Benjamin; Ritacco, Viviana; Balloux, Francois (November 2015)."Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain".Nature Communications.6 (1): 7119.Bibcode:2015NatCo...6.7119E.doi:10.1038/ncomms8119.ISSN 2041-1723.PMC 4432642.PMID 25960343.
  10. ^Eldholm, Vegard; Rieux, Adrien; Monteserin, Johana; Lopez, Julia Montana; Palmero, Domingo; Lopez, Beatriz; Ritacco, Viviana; Didelot, Xavier; Balloux, Francois (2016-08-09)."Impact of HIV co-infection on the evolution and transmission of multidrug-resistant tuberculosis".eLife.5: e16644.doi:10.7554/eLife.16644.ISSN 2050-084X.PMC 4978521.PMID 27502557.
  11. ^Wang, Ruobing; van Dorp, Lucy; Shaw, Liam P.; Bradley, Phelim; Wang, Qi; Wang, Xiaojuan; Jin, Longyang; Zhang, Qing; Liu, Yuqing; Rieux, Adrien; Dorai-Schneiders, Thamarai (December 2018)."The global distribution and spread of the mobilized colistin resistance gene mcr-1".Nature Communications.9 (1): 1179.Bibcode:2018NatCo...9.1179W.doi:10.1038/s41467-018-03205-z.ISSN 2041-1723.PMC 5862964.PMID 29563494.
  12. ^Acman, Mislav; van Dorp, Lucy; Santini, Joanne M.; Balloux, Francois (December 2020)."Large-scale network analysis captures biological features of bacterial plasmids".Nature Communications.11 (1): 2452.Bibcode:2020NatCo..11.2452A.doi:10.1038/s41467-020-16282-w.ISSN 2041-1723.PMC 7229196.PMID 32415210.
  13. ^Shaw, Liam P.; Wang, Alethea D.; Dylus, David; Meier, Magda; Pogacnik, Grega; Dessimoz, Christophe; Balloux, François (2020)."The phylogenetic range of bacterial and viral pathogens of vertebrates".Molecular Ecology.29 (17):3361–3379.doi:10.1111/mec.15463.ISSN 1365-294X.PMID 32390272.S2CID 218586409.
  14. ^van Dorp, Lucy; Acman, Mislav; Richard, Damien; Shaw, Liam P.; Ford, Charlotte E.; Ormond, Louise; Owen, Christopher J.; Pang, Juanita; Tan, Cedric C. S.; Boshier, Florencia A. T.; Ortiz, Arturo Torres; Balloux, François (2020-09-01)."Emergence of genomic diversity and recurrent mutations in SARS-CoV-2".Infection, Genetics and Evolution.83: 104351.doi:10.1016/j.meegid.2020.104351.ISSN 1567-1348.PMC 7199730.PMID 32387564.

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