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Facet cell

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Specialised epithelial cells found in the urinary system
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Facet cells (also known asumbrella cells,[1] capping cells, superficial urotheliocytes) are a type of cells located in therenal pelvis, theureters, and theurethra. Umbrella cells form the outermost layer of theurothelium, which is a special type ofepithelium found in therenal pelvis, theureters, and theurethra. Umbrella cells are special in that they can containmultiple nuclei. Theirapical membrane contains numerousinvaginations, which allows the cells to stretch duringurination. Umbrella cells are linked together with tightjunctions which:

Umbrella cells containuroplakin ia,uroplakin ib, uroplakin ii, and uroplakin iii.[3] These increase the strength of theurothelium.[3]

References

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  1. ^Born, Martin; Pahner, Ingrid; Ahnert-Hilger, Gudrun; Jöns, Thomas (July 2003). "The maintenance of the permeability barrier of bladder facet cells requires a continuous fusion of discoid vesicles with the apical plasma membrane".European Journal of Cell Biology.82 (7):343–350.doi:10.1078/0171-9335-00326.PMID 12924629.
  2. ^Lüllman-Rauch (2008).Histologie 1er cycle des études médicales. De Boeck Supérieur.ISBN 9782804156923.
  3. ^abRiedel, Ina; Liang, Feng-Xia; Deng, Fang-Ming; Tu, Liyu; Kreibich, Gert; Wu, Xue-Ru; Sun, Tung-Tien; Hergt, Michaela; Moll, Roland (2005-03-09)."Urothelial umbrella cells of human ureter are heterogeneous with respect to their uroplakin composition: different degrees of urothelial maturity in ureter and bladder?".European Journal of Cell Biology.84 (2–3):393–405.doi:10.1016/j.ejcb.2004.12.011.ISSN 0171-9335.PMID 15819416.


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