As of 2024, focus is particularly on exposure and response prevention (ERP or ExRP) therapy, in which exposure is continued and the resolution to refrain from the escape response is maintained at all times (not just during specific therapy sessions).[6][7][8][9]
Exposure therapy is based on the principle ofrespondent conditioning often termed Pavlovian extinction.[10] The exposure therapist identifies the cognitions, emotions and physiological arousal that accompany a fear-inducing stimulus and then tries to break the pattern of escape that maintains the fear. This is done by exposing the patient to fear-inducing stimuli.[11]
This may be done:
using progressively stronger stimuli. Fear is minimized at each of a series of steadily escalating steps or challenges (ahierarchy), which can be explicit ("static") or implicit ("dynamic" — seeMethod of Factors) until the fear is finally gone.[12] The patient is able to terminate the procedure at any time.
In vivo or "real life".[15] This type exposes the patient to actual fear-inducing situations. For example, if someone fears public speaking, the person may be asked to give a speech to a small group of people.
Virtual reality, in which technology is used to simulate in vivo exposure.
Imaginal, where patients are asked to imagine a situation that they are afraid of. This procedure is helpful for people who need to confront feared thoughts and memories.
Interoceptive, in which patients confront feared bodily symptoms such as increased heart rate and shortness of breath. This may be used for more specific disorders such aspanic orpost-traumatic stress disorder.
The various types of exposure may be used together or separately.[16][17][18] Discussion continues on how best to carry out exposure therapy, including on whether safety behaviours should be discontinued.[19][20]
In the exposure and response prevention (ERP or EX/RP) form of exposure therapy, the resolution to refrain from theescape response is to be maintained at all times (not just during specific practice sessions).[21] Thus, not only does the subject experiencehabituation to the feared stimulus, but they also practice a fear-incompatible behavioral response to the stimulus. The distinctive feature is that individuals confront their fears and discontinue their escape response.[22]
While this type of therapy typically causes some short-term anxiety, this facilitates long-term reduction in obsessive and compulsive symptoms.[23][24]: 103 [9]
The American Psychiatric Association recommends ERP for the treatment ofOCD, citing that ERP has the richest empirical support.[25] As of 2019, ERP is considered a first-line psychotherapy for OCD.[21][26] A 2024 systematic review found that ERP is highly effective in treating pediatric OCD using both in-person and telehealth-based modailites.[27]
Effectiveness is heterogeneous. Higher efficacy correlates with lower avoidance behaviours, and greater adherence to homework. UsingSSRI meds whilst doing ERP does not appear to correlate with better outcomes.[28][29][30] Discussion continues on how to best conduct ERP.[31]
Generally, ERP incorporates arelapse prevention plan toward the end of the course of therapy.[21] This can include being ready to re-apply ERP if an anxiety does occur.[32]
As of 2022, the inhibitory learning model is the most common conjecture of the mechanism which causes exposure therapy efficacy. This model posits that in exposure therapy the unpleasant reactions such as anxiety (that were previously learned during fear conditioning) remain intact - they are not expected to be eliminated - but that they are now inhibited or balanced or overcome by new learning about the situation (for instance that the feared result will not necessarily happen).[20][35][36][37] More research is needed.[38]
This model posits that additional associative learning processes, such as counterconditioning and novelty-enhanced extinction may contribute to exposure therapy.[39][40]
Exposure therapy is seen as under-used in relation to its efficacy.[41] Barriers to use of exposure therapy by psychologists include it appearing antithetical to mainline psychology,[41] lack of confidence, and negative beliefs about exposure therapy.[42]
Exposure therapy is the most successful known treatment for phobias.[43] Several published meta-analyses included studies of one-to-three-hour single-session treatments of phobias, using imaginal exposure. At a post-treatment follow-up four years later 90% of people retained a considerable reduction in fear, avoidance, and overall level of impairment, while 65% no longer experienced any symptoms of a specific phobia.[15]
Exposure therapy inPTSD involves exposing the patient to PTSD-anxiety triggering stimuli, with the aim of weakening the neural connections between triggers and trauma memories (a.k.a.desensitisation). Exposure may involve:[18]
Narrative exposure therapy - creates a written account of the traumatic experiences of a patient or group of patients, in a way that serves to recapture their self-respect and acknowledges their value. Under this name it is used mainly with refugees, in groups.[45] It also forms an important part ofcognitive processing therapy[citation needed] and is conditionally recommended for treatment of PTSD by theAmerican Psychological Association.[45]
Prolonged exposure therapy (PE) - a form ofbehavior therapy andcognitive behavioral therapy designed to treatpost-traumatic stress disorder, characterized by two main treatment procedures – imaginal and in vivo exposures. Imaginal exposure is a repeated 'on-purpose' retelling of the trauma memory. In vivo exposure is gradually confronting situations, places, and things that are reminders of the trauma or feel dangerous (despite being objectively safe). Additional procedures include processing of the trauma memory and breathing retraining. TheAmerican Psychological Association strongly recommends PE as a first-line psychotherapy treatment for PTSD.[46]
Researchers began experimenting withVirtual reality exposure (VRE) therapy in PTSD exposure therapy in 1997 with the advent of the "Virtual Vietnam" scenario. Virtual Vietnam was used as a graduated exposure therapy treatment for Vietnam veterans meeting the qualification criteria for PTSD. A 50-year-old Caucasian male was the first veteran studied. The preliminary results concluded improvement post-treatment across all measures of PTSD and maintenance of the gains at the six-month follow up. Subsequent open clinical trial of Virtual Vietnam using 16 veterans, showed a reduction in PTSD symptoms.[47][48]
This method was also tested on several active duty Army soldiers, using an immersive computer simulation of military settings over six sessions. Self-reported PTSD symptoms of these soldiers were greatly diminished following the treatment.[49][dubious –discuss] Exposure therapy has shown promise in the treatment ofco-morbid PTSD andsubstance abuse.
In the area of PTSD, historic barriers to the use of exposure therapy include that clinicians may not understand it, are not confident in their own ability to use it, or more commonly, see significantcontraindications for their client.[50][51]
Exposure and response prevention (also known as exposure and ritual prevention; ERP or EX/RP) is a variant of exposure therapy that is recommended by the American Academy of Child and Adolescent Psychiatry (AACAP), the American Psychiatric Association (APA), and the Mayo Clinic as first-line treatment ofOCD citing that it has the richest empirical support for both youth and adolescent outcomes.[25][52]
ERP is predicated on the idea that atherapeutic effect is achieved as subjects confront their fears, but refrain from engaging in the escape response or ritual that delays or eliminates distress.[22] In the case of individuals with OCD or an anxiety disorder, there is a thought or situation that causes distress. Individuals usually combat this distress through specific behaviors that include avoidance or rituals. However, ERP involves purposefully evoking fear, anxiety, and or distress in the individual by exposing him/her to the feared stimulus.[15] The response prevention then involves having the individual refrain from the ritualistic or otherwise compulsive behavior that functions to decrease distress. The patient is then taught to tolerate distress until it fades away on its own, thereby learning that rituals are not always necessary to decrease distress or anxiety. Over repeated practice of ERP, patients with OCD expect to find that they can have obsessive thoughts and images but not have the need to engage incompulsive rituals to decrease distress.[25][52]
The AACAP's practice parameters for OCD recommends cognitive behavioral therapy, and more specifically ERP, as first line treatment for youth with mild to moderate severity OCD and combination psychotherapy and pharmacotherapy for severe OCD.[52] TheCochrane Review's examinations of different randomized control trials echoes repeated findings of the superiority of ERP over waitlist control or pill-placebos, the superiority of combination ERP and pharmacotherapy, but similar effect sizes of efficacy between ERP or pharmacotherapy alone.[53]
There is empirical evidence that exposure therapy can be an effective treatment for people withgeneralized anxiety disorder, citing specifically in vivo exposure therapy (exposure through a real-life situation),[15] which has greater effectiveness than imaginal exposure in regards to generalized anxiety disorder. The aim of in vivo exposure treatment is to promote emotional regulation using systematic and controlled therapeutic exposure to traumatic stimuli.[54] Exposure is used to promote fear tolerance.[55]
Exposure therapy is also a preferred method for children who struggle with anxiety.[56]
The 9th century Persian polymathAbu Zayd al-Balkhi wrote about 'tranquilizing fear' by 'forcing oneself to repeatedly expose one's hearing and sight to noxious things' and to 'moved again and again near the thing it is scared of until it becomes used to it and loses its fear.'[64]
The use of exposure as a mode of therapy began in the 1950s, at a time whenpsychodynamic views dominated Western clinical practice andbehavioral therapy was first emerging. South African psychologists and psychiatrists first used exposure as a way to reduce pathological fears, such as phobias and anxiety-related problems, and they brought their methods to England in theMaudsley Hospital training program.[22]
Joseph Wolpe (1915–1997) was one of the first psychiatrists to spark interest in treating psychiatric problems as behavioral issues. He sought consultation with other behavioral psychologists, among them James G. Taylor (1897–1973), who worked in the psychology department of theUniversity of Cape Town in South Africa. Although most of his work went unpublished, Taylor was the first psychologist known to use exposure therapy treatment foranxiety, including methods of situational exposure with response prevention—a common exposure therapy technique still being used.[22]Since the 1950s, several sorts of exposure therapy have been developed, includingsystematic desensitization,flooding, implosive therapy,prolonged exposure therapy, in vivo exposure therapy, and imaginal exposure therapy.[22]
Exposure and response prevention (ERP) traces its roots back to the work of psychologistVic Meyer in the 1960s. Meyer devised this treatment from his analysis offear extinguishment in animals viaflooding and applied it to human cases in the psychiatric setting that, at the time, were considered intractable.[65] The success of ERP clinically and scientifically has been summarized as "spectacular" by prominent OCD researcherStanley Rachman decades following Meyer's creation of the method.[66]
A 2015 review pointed out parallels between exposure therapy andmindfulness, stating that mindful meditation "resembles an exposure situation because [mindfulness] practitioners 'turn towards their emotional experience', bring acceptance to bodily and affective responses, and refrain from engaging in internal reactivity towards it."[67] Imaging studies have shown that theventromedial prefrontal cortex,hippocampus, and theamygdala are all affected by exposure therapy; imaging studies have shown similar activity in these regions with mindfulness training.[67]
Exposure therapy can be investigated in the laboratory using Pavlovianextinction paradigms. Using rodents such as rats or mice to study extinction allows for the investigation of underlying neurobiological mechanisms involved, as well as testing of pharmacological adjuncts to improve extinction learning.[69][70]
^For example, a person withpanic disorder may be told to run in place, causing their heart to race, so that they can see that this feeling is not dangerous.
^Joseph JS, Gray MJ (2008). "Exposure Therapy for Posttraumatic Stress Disorder".Journal of Behavior Analysis of Offender and Victim: Treatment and Prevention.1 (4):69–80.doi:10.1037/h0100457.
^Huppert JD, Roth DA (2003). "Treating obsessive-compulsive disorder with exposure and response prevention".The Behavior Analyst Today.4 (1):66–70.doi:10.1037/h0100012.
^Song Y, Li D, Zhang S, Jin Z, Zhen Y, Su Y, Zhang M, Lu L, Xue X, Luo J, Liang M, Li X (November 2022). "The effect of exposure and response prevention therapy on obsessive-compulsive disorder: A systematic review and meta-analysis".Psychiatry Research.317: 114861.doi:10.1016/j.psychres.2022.114861.PMID36179591.S2CID252530334.
^Marks IM (1981).Cure and care of neuroses: theory and practice of behavioral psychotherapy. New York: Wiley.ISBN978-0-471-08808-0.[page needed]
^De Silva P, Rachman S (1981). "Is exposure a necessary condition for fear-reduction?".Behaviour Research and Therapy.19 (3):227–232.doi:10.1016/0005-7967(81)90006-1.PMID6117277.
^Miltenberger RG (2008).Behavioral Modification: Principles and Procedures (4th ed.).Thomson/Wadsworth. p. 552.
^"The best treatment for OCD is CBT which typically includes exposure and response prevention (ERP) and some degree of more cognitive interventions.""Relapse Prevention in the Treatment of OCD".
^Ong CW, Petersen JM, Terry CL, Krafft J, Barney JL, Abramowitz JS, Twohig MP (April 2022). "The 'how' of exposures: Examining the relationship between exposure parameters and outcomes in obsessive-compulsive disorder".Journal of Contextual Behavioral Science.24:87–95.doi:10.1016/j.jcbs.2022.03.009.S2CID247802575.
^Sewart AR, Craske MG."Inhibitory learning.". In Abramowitz JS, Blakey SM (eds.).Clinical handbook of fear and anxiety: Maintenance processes and treatment mechanisms. American Psychological Association. pp. 265–285.
^Brevers D, Philippot P (3 November 2023). "An inhibitory retrieval approach for maximizing exposure therapy in elite sport".Journal of Applied Sport Psychology.35 (6):941–959.doi:10.1080/10413200.2023.2166154.S2CID255798306.
^Moses K, Gonsalvez CJ, Meade T (April 2023). "Barriers to the use of exposure therapy by psychologists treating anxiety, obsessive-compulsive disorder, and posttraumatic stress disorder in an Australian sample".Journal of Clinical Psychology.79 (4):1156–1165.doi:10.1002/jclp.23470.PMID36449416.S2CID254093759.
^Rizzo A, Rothbaum BO, Graap K (2011). "Virtual reality applications for combat-related posttraumatic stress disorder". In Figley CR, Nash WP (eds.).Combat Stress Injury: Theory, Research, and Management. Routledge. pp. 183–204.ISBN978-1-135-91933-7.
^Rizzo A, Roy MJ, Hartholt A, Costanzo M, Highland KB, Jovanovic T, Norrholm SD, Reist C, Rothbaum B, Difede J (2017). "Virtual Reality Applications for the Assessment and Treatment of PTSD".Handbook of Military Psychology. pp. 453–471.doi:10.1007/978-3-319-66192-6_27.ISBN978-3-319-66190-2.DTICAD1160293.
^Reger GM, Gahm GA (August 2008). "Virtual reality exposure therapy for active duty soldiers".Journal of Clinical Psychology.64 (8):940–946.doi:10.1002/jclp.20512.PMID18612993.
^Parsons TD, Rizzo AA (September 2008). "Affective outcomes of virtual reality exposure therapy for anxiety and specific phobias: a meta-analysis".Journal of Behavior Therapy and Experimental Psychiatry.39 (3):250–261.doi:10.1016/j.jbtep.2007.07.007.PMID17720136.S2CID6688068.
^"Instead of teaching patients to resist, control or "fix" their fear or anxiety, exposure is used to promote 'fear tolerance' given that fear and anxiety are universal, inevitable and safe." Exposure Therapy for Anxiety, Second Edition (2019), p18, Abramowitz, Deacon and Whiteside
^Hayes AM, Yasinski C, Alpert E (2022). "The Application of Exposure Principles to the Treatment of Depression".Clinical Guide to Exposure Therapy. pp. 317–345.doi:10.1007/978-3-031-04927-9_17.ISBN978-3-031-04926-2.
^Springer KS, Colin DF (2020).The Big Book of Exposures: Innovative, Creative, and Effective CBT-Based Exposures for Treating Anxiety-Related Disorders. Oakland, CA: New Harbinger Publications.ISBN978-1-68403-373-7.
^Richard DC, Lauterbach D (2006).Handbook of Exposure Therapies Hardcover. Elsevier.ISBN978-0-08-046781-8.
^Meyer V (November 1966). "Modification of expectations in cases with obsessional rituals".Behaviour Research and Therapy.4 (4):273–280.doi:10.1016/0005-7967(66)90023-4.PMID5978682.