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EP400

From Wikipedia, the free encyclopedia
Protein-coding gene in humans
EP400
Identifiers
AliasesEP400, CAGH32, P400, TNRC12, E1A binding protein p400
External IDsOMIM:606265;MGI:1276124;HomoloGene:38779;GeneCards:EP400;OMA:EP400 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for EP400
Genomic location for EP400
Band12q24.33Start131,949,942bp[1]
End132,080,460bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for EP400
Genomic location for EP400
Band5|5 FStart110,812,239bp[2]
End110,918,583bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tendon of biceps brachii

  • sural nerve

  • secondary oocyte

  • ventricular zone

  • internal globus pallidus

  • right uterine tube

  • right hemisphere of cerebellum

  • left ovary

  • testicle

  • right ovary
Top expressed in
  • zygote

  • spermatocyte

  • seminiferous tubule

  • tail of embryo

  • ventricular zone

  • genital tubercle

  • Rostral migratory stream

  • secondary oocyte

  • spermatid

  • neural layer of retina
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

57634

75560

Ensembl

ENSG00000183495

ENSMUSG00000029505

UniProt

Q96L91

Q8CHI8

RefSeq (mRNA)

NM_015409

NM_029337
NM_173066

RefSeq (protein)

NP_056224

NP_083613
NP_775089

Location (UCSC)Chr 12: 131.95 – 132.08 MbChr 5: 110.81 – 110.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

E1A-binding protein p400 is aprotein that in humans is encoded by theEP400gene.[5][6][7]

Interactions

[edit]

EP400 has been shown tointeract withTransformation/transcription domain-associated protein,[6]RuvB-like 1[6] andMyc.[6]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000183495 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000029505 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (Jul 1997). "cDNAs with long CAG trinucleotide repeats from human brain".Hum Genet.100 (1):114–22.doi:10.1007/s004390050476.PMID 9225980.S2CID 25999127.
  6. ^abcdFuchs M, Gerber J, Drapkin R, Sif S, Ikura T, Ogryzko V, Lane WS, Nakatani Y, Livingston DM (Aug 2001)."The p400 complex is an essential E1A transformation target".Cell.106 (3):297–307.doi:10.1016/S0092-8674(01)00450-0.PMID 11509179.S2CID 15634637.
  7. ^"Entrez Gene: EP400 E1A binding protein p400".

Further reading

[edit]


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