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| Names | |
|---|---|
| IUPAC name ethyl-[4-[[4-[ethyl-[(3-sulfophenyl)methyl]amino]phenyl]-(4-hydroxy-2-sulfophenyl)methylidene]-1-cyclohexa-2,5-dienylidene]-[(3-sulfophenyl)methyl]azanium | |
Other names
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| Identifiers | |
3D model (JSmol) | |
| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.017.356 |
| EC Number |
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| E number | E143(colours) |
| KEGG |
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| UNII | |
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| Properties | |
| C37H34N2Na2O10S3 | |
| Molar mass | 808.84 g·mol−1 |
| Hazards[1] | |
| GHS labelling: | |
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| Warning | |
| H315,H319,H335 | |
| P201,P202,P261,P264,P271,P280,P281,P302+P352,P304+P340,P305+P351+P338,P308+P313,P312,P321,P332+P313,P337+P313,P362,P403+P233,P405,P501 | |
| NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Fast Green FCF, also calledFood green 3,FD&C Green No. 3,Green 1724,Solid Green FCF, andC.I. 42053, is aturquoise triarylmethanefood dye. ItsE number is E143.
Fast Green FCF is recommended as a replacement ofLight Green SF yellowish inMasson's trichrome, as its color is more brilliant and less likely to fade. It is used as a quantitativestain forhistones at alkaline pH after acid extraction ofDNA. It is also used as a protein stain inelectrophoresis. Its absorption maximum is at 625 nm.
Fast Green FCF is poorly absorbed by the intestines.[2] Its use as a food dye is prohibited in theEuropean Union and some other countries. In the United States, Fast Green FCF is the least used of the seven main FDA approved dyes.
A reevaluation of Fast Green FCF published by the World Health Organization in 2017 concluded that it has low toxicity and is not carcinogenic or genotoxic, and that there were no health concerns with consumption of Fast Green FCF at the previously established allowable daily intake (which itself is much higher than estimates of actual dietary exposure to Fast Green FCF).[3]
