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| Names | |
|---|---|
| IUPAC name 2′-Deoxycytidylic acid | |
| Systematic IUPAC name [(2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
|
| ECHA InfoCard | 100.012.591 |
| MeSH | Deoxycytidine+monophosphate |
| UNII | |
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| Properties | |
| C9H14N3O7P | |
| Molar mass | 307.199 g·mol−1 |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Deoxycytidine monophosphate (dCMP), also known asdeoxycytidylic acid ordeoxycytidylate in itsconjugate acid and conjugate base forms, respectively, is adeoxynucleotide and one of the fourmonomers that make upDNA. In a DNA double helix, it will base pair withdeoxyguanosine monophosphate.[1]
Deoxycytidine monophosphate is a molecule of interest in treating genetic disorders such as thymidine kinase 2 (TK2) deficiency. In the case ofTK2 deficiency, dCMP in conjunction withdeoxythymidine monophosphate (dTMP) to bypass the deficiency in theTK2 enzyme.[2] Additionally dCMP is an indicator of several metabolite deficiency pathways such as UMP synthase deficiency ororotic aciduria.[3]
