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DESOXY

From Wikipedia, the free encyclopedia
Not to be confused withDesoxyn.
This articlerelies largely or entirely on asingle source. Relevant discussion may be found on thetalk page. Please helpimprove this article byintroducing citations to additional sources.
Find sources: "DESOXY" – news ·newspapers ·books ·scholar ·JSTOR
(April 2015)
DESOXY
Names
Preferred IUPAC name
2-(3,5-Dimethoxy-4-methylphenyl)ethan-1-amine
Other names
3,5-Dimethoxy-4-methylphenethylamine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C11H17NO2/c1-8-10(13-2)6-9(4-5-12)7-11(8)14-3/h6-7H,4-5,12H2,1-3H3 checkY
    Key: LLHRMWHYJGLIEV-UHFFFAOYSA-N checkY
  • InChI=1/C11H17NO2/c1-8-10(13-2)6-9(4-5-12)7-11(8)14-3/h6-7H,4-5,12H2,1-3H3
    Key: LLHRMWHYJGLIEV-UHFFFAOYAV
  • Cc1c(cc(cc1OC)CCN)OC
Properties
C11H17NO2
Molar mass195.26 g/mol
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Chemical compound

4-Desoxymescaline, or4-methyl-3,5-dimethoxyphenethylamine, is amescalineanalogue related to otherpsychedelicphenethylamines. It is commonly referred to asDESOXY. DESOXY was discovered byAlexander Shulgin and published in his bookPiHKAL.

Effects

[edit]

The effects of DESOXY vary significantly frommescaline, despite their chemical similarity.[citation needed]

Dosage

[edit]

A typical dosage is within the range of 40–120 mg and lasts 6–8 hours.[1]

Pharmacology

[edit]

DESOXY acts as aserotonin5-HT2 receptoragonist.[2]

Legality

[edit]

In 1970 theControlled Substances Act placedmescaline intoSchedule I in theUnited States. It is similarly controlled in other nations. Depending on whether or not it is intended for human consumption, 4-desoxymescaline could be considered ananalogue ofmescaline, under theFederal Analogue Act and similar bills in other countries, making it illegal to manufacture, buy, possess, or distribute without a DEA or related license.

DESOXY is also an isomer of2C-D which makes it a schedule 1 drug in the United States.

See also

[edit]

References

[edit]
  1. ^Shulgin, Alexander;Ann Shulgin (September 1991).PiHKAL: A Chemical Love Story.Berkeley, California: Transform Press.ISBN 0-9630096-0-5.OCLC 25627628.
  2. ^Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD (December 2023)."Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential".Nat Commun.14 (1): 8221.doi:10.1038/s41467-023-44016-1.PMC 10724237.PMID 38102107.

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