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Cervical rib

From Wikipedia, the free encyclopedia

Cervical ribs are theribs of theneck in manytetrapods. In most mammals, including humans, cervical ribs are not normally present as separate structures. They can, however, occur as a pathology. In humans, pathological cervical ribs are usually not of clinical concern, although they can cause a form ofthoracic outlet syndrome.

Development

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Like other ribs, the cervical ribs form byendochondral ossification.[1]

Variation

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The cervical ribs ofsauropoddinosaurs were extended by ossifiedtendons,[2] and could reach exceptional lengths; a cervical rib ofMamenchisaurus sinocanadorum was 4.2 metres (14 ft) long.[3]

Inbirds, the cervical ribs are small and completely fused to the vertebrae.

Intherianmammals, the cervical ribs fully fuse with thecervical vertebrae to form part of thetransverse processes, except in rare pathological cases. In contrast,monotremes retain the plesiomorphic condition of having separate cervical ribs.[4]

Pathological cervical ribs

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Medical condition
Cervical rib
Other namesNeck ribs[5]
SpecialtyThoracic surgery

Acervical rib in humans is anextrarib which arises from the seventhcervical vertebra. Their presence is acongenital abnormality located above the normal first rib. A cervical rib is estimated to occur in 0.2%[6] to 0.5%[7] (1 in 200 to 500) of the population.[8] People may have a cervical rib on the right, left or both sides.[9][10]

Most cases of cervical ribs are not clinically relevant and do not have symptoms;[11][12] cervical ribs are generally discoveredincidentally, most often duringx-rays andCT scans.[7][8][10] However, they vary widely in size and shape,[7] and in rare cases, they may cause problems such as contributing tothoracic outlet syndrome,[11] because of pressure on thenerves that may be caused by the presence of the rib.[11][13]

A cervical rib represents a persistentossification of the C7 lateral costal element.[11][12] During early development, this ossified costal element typically becomes re-absorbed. Failure of this process results in a variably elongated transverse process or complete rib that can be anteriorly fused with the T1 first rib below.[14]

Diagnosis

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3D CT reconstruction of a cervical rib.
Bilateral, symmetric, full, ossified cervical ribs.

On imaging, cervical ribs can be distinguished because their transverse processes are directed inferolaterally, whereas those of the adjacent thoracic spine are directedanterolaterally.[15]

Associated conditions

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The presence of a cervical rib can cause a form ofthoracic outlet syndrome due to compression of the lower trunk of thebrachial plexus orsubclavian artery.[11] These structures become encroached upon by the cervical rib andscalene muscles.

Compression of the brachial plexus may be identified by weakness of the muscles in the hand, near the base of the thumb. Compression of the subclavian artery is often diagnosed by finding a positiveAdson's sign on examination, where the radialpulse in the arm is lost duringabduction andexternal rotation of theshoulder.[11] A positive Adson's sign is non-specific for the presence of a cervical rib however, as many individuals without a cervical rib will have a positive test. Compression of the sympathetic chain may causeHorner's syndrome.

In other animals

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Recent studies have also found a high percent of cervical ribs in woolly mammoths. It is believed that the decline in mammoth numbers may have forced inbreeding within the species which in turn had increased the number of mammoths being born with cervical ribs. Cervical ribs have been connected withleukaemia in human children, so it has given scientists new evidence to believe that the mammoth's extinction was attributed to the condition.[16] They have also been interpreted as a sign ofinbreeding depression in other mammals, such asMegaloceros.[17]

References

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  1. ^Romer, Alfred Sherwood (1956).Osteology of the Reptiles.
  2. ^Klein, Nicole; Christian, Andreas; Sander, P. Martin (2012-12-23)."Histology shows that elongated neck ribs in sauropod dinosaurs are ossified tendons".Biology Letters.8 (6):1032–1035.doi:10.1098/rsbl.2012.0778.eISSN 1744-957X.ISSN 1744-9561.PMC 3497149.PMID 23034173.
  3. ^Moore, Andrew J.; Barrett, Paul M.; Upchurch, Paul; Liao, Chun-Chi; Ye, Yong; Hao, Baoqiao; Xu, Xing (2023-03-15). "Re-assessment of the Late Jurassic eusauropod Mamenchisaurus sinocanadorum Russell and Zheng, 1993, and the evolution of exceptionally long necks in mamenchisaurids".Journal of Systematic Palaeontology.21 (1).Bibcode:2023JSPal..2171818M.doi:10.1080/14772019.2023.2171818.ISSN 1477-2019.
  4. ^Weisbecker, Vera (2011). "Monotreme ossification sequences and the riddle of mammalian skeletal development".Evolution.65 (5):1323–1335.doi:10.1111/j.1558-5646.2011.01234.x.eISSN 1558-5646.ISSN 0014-3820.PMID 21521190.
  5. ^Selim, Jocelyn."Useless Body Parts".
  6. ^Galis F (1999)."Why do almost all mammals have seven cervical vertebrae? Developmental constraints, Hox genes, and cancer".J. Exp. Zool.285 (1):19–26.Bibcode:1999JEZ...285...19G.doi:10.1002/(SICI)1097-010X(19990415)285:1<19::AID-JEZ3>3.0.CO;2-Z.PMID 10327647. Archived fromthe original on 2013-01-06.
  7. ^abcTerry Yochum; Lindsay Rowe (2005).Essentials of Skeletal Radiology (3 ed.). Lippencott & Williams.
  8. ^abRochkind, Shimon; Zager, Eric (2012-01-01), Quiñones-Hinojosa, Alfredo (ed.),"Chapter 205 - Management of Thoracic Outlet Syndrome",Schmidek and Sweet Operative Neurosurgical Techniques (Sixth Edition), Philadelphia: W.B. Saunders, pp. 2339–2348,doi:10.1016/b978-1-4160-6839-6.10205-9,ISBN 978-1-4160-6839-6, retrieved2020-10-23
  9. ^Oner, Zulal; Oner, Serkan; Sahin, Necati Emre; Cay, Mahmut (26 January 2023)."Evaluation of congenital rib anomalies with multi-detector computed tomography in the Turkish population".Folia Morphologica.83 (1):182–191.doi:10.5603/FM.a2023.0006.PMID 36794687.S2CID 256899032.
  10. ^abWalden, Michael; et al. (2013). "Cervical ribs: identification on MRI and clinical relevance".Clinical Imaging.37 (5):938–941.doi:10.1016/j.clinimag.2013.01.005.PMID 23759210.
  11. ^abcdefGiles, Lynton G. F. (2009-01-01), Giles, Lynton G. F. (ed.),"Case 67 - Cervical ribs",100 Challenging Spinal Pain Syndrome Cases (Second Edition), Edinburgh: Churchill Livingstone, pp. 311–314,doi:10.1016/b978-0-443-06716-7.00067-0,ISBN 978-0-443-06716-7, retrieved2020-10-23
  12. ^abTani, Edneia M.; Skoog, Lambert (2008-01-01), Bibbo, Marluce; Wilbur, David (eds.),"CHAPTER 22 - Salivary Glands and Rare Head and Neck Lesions",Comprehensive Cytopathology (Third Edition), Edinburgh: W.B. Saunders, pp. 607–632,ISBN 978-1-4160-4208-2, retrieved2020-10-23
  13. ^Guttentag, Adam; Salwen, Julia (1999). "Keep Your Eyes on the Ribs: The Spectrum of Normal Variants and Diseases That Involve the Ribs".RadioGraphics.19 (5):1125–1142.doi:10.1148/radiographics.19.5.g99se011125.PMID 10489169.
  14. ^E. McNally,B. Sandin &R. A. Wilkins (June 1990)."The ossification of the costal element of the seventh cervical vertebra with particular reference to cervical ribs".Journal of Anatomy.170:125–129.PMC 1257068.PMID 2123844.
  15. ^Balan, Nisha Sharma, Anu (2008).Get through FRCR part 2B : rapid reporting of plain radiographs. London: Royal Society of Medicine.ISBN 978-1853157547.{{cite book}}: CS1 maint: multiple names: authors list (link)
  16. ^"Woolly Mammoths Suffered Major Birth Defects Before Extinction".IFLScience. 25 March 2014.
  17. ^Cuxart-Erruz, Raimon; Van Dooren, Tom J. M.; van der Geer, Alexandra A. E.; Galis, Frietson (2024-09-24)."Increased incidences of cervical ribs in deer indicate extinction risk".Proceedings of the National Academy of Sciences.121 (39): –2406670121.Bibcode:2024PNAS..12106670C.doi:10.1073/pnas.2406670121.PMC 11441530.PMID 39284067.

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