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Chemical and physical data | |
Formula | C15H20Cl2N2 |
Molar mass | 299.24 g·mol−1 |
3D model (JSmol) | |
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BD1031 or(R)-2-[2-(3,4-dichlorophenyl)ethyl]octahydropyrrolo[1,2-a]pyrazine is a selectivesigma receptoragonist, with a reportedbinding affinity ofKi = 1 ± 0.2 nM for thesigma-1 receptor and 80 times selectivity over thesigma-2 receptor.[1] The enantiomer of BD1031 is known asBD1018.
Consistent with other reportedsigma receptoragonists, BD1031 increases the behavioural toxicity of cocaine in Swiss Webster mice.[1]