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Ancarolol

From Wikipedia, the free encyclopedia

Chemical compound

Pharmaceutical compound

Ancarolol
Clinical data

ATC code	none
Identifiers
IUPAC name N-[2-[3-(tert-Butylamino)-2-hydroxy-propoxy]phenyl]furan-2-carboxamide
CAS Number	75748-50-4^Y
PubChemCID	170339
ChemSpider	148938^Y
UNII	00EED65INL
ChEMBL	ChEMBL1742449^N
CompTox Dashboard(EPA)	DTXSID50868379
Chemical and physical data
Formula	C₁₈H₂₄N₂O₄
Molar mass	332.400 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(Nc1ccccc1OCC(O)CNC(C)(C)C)c2occc2
InChI InChI=1S/C18H24N2O4/c1-18(2,3)19-11-13(21)12-24-15-8-5-4-7-14(15)20-17(22)16-9-6-10-23-16/h4-10,13,19,21H,11-12H2,1-3H3,(H,20,22)^Y Key:XBRNQRFNEAHCPR-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Ancarolol is abeta blocker.^[1]

References

^"The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived fromthe original on March 7, 2012.

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Sympatholytic (and closely related)antihypertensives (C02)

Sympatholytics
(antagonizeα-adrenergic
vasoconstriction)

Central

α₂-Adrenergic receptor agonists	Clonidine Guanabenz Guanfacine Guanoxabenz Methyldopa^# Tiamenidine^‡
Adrenergic release inhibitors	Bethanidine Bretylium Debrisoquine Guanadrel Guanazodine Guancydine Guanethidine Guanoclor Guanoxan
Imidazoline receptor agonists	Moxonidine Rilmenidine Tolonidine
Ganglion-blocking/nicotinic antagonists	Hexamethonium^‡ Mecamylamine Pentolinium Trimethaphan

Peripheral

Indirect

Monoamine oxidase inhibitors	Pargyline^‡
VMAT inhibitors	Bietaserpine Deserpidine Methoserpidine Reserpine Syrosingopine
Tyrosine hydroxylase inhibitors	Metirosine

Direct

α₁-Adrenergic receptor blockers	Doxazosin Ketanserin Indoramin Prazosin Trimazosin Urapidil
Non-selective α-adrenergic receptor blockers	Phentolamine

Otherantagonists

Serotonin receptor antagonists	Ketanserin Lidanserin
Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension)	dual (Aprocitentan,Bosentan,Macitentan (+tadalafil),Riociguat) selective (Ambrisentan (+tadalafil),Sitaxentan,Sotatercept)

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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Adrenergic receptor modulators

Agonists

Antagonists

Agonists

Antagonists

Agonists

Antagonists

See also:Receptor/signaling modulators
Dopaminergics
Serotonergics
Monoamine reuptake inhibitors
Monoamine releasing agents
Monoamine metabolism modulators
Monoamine neurotoxins

Thisantihypertensive-related article is astub. You can help Wikipedia byexpanding it.

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