US: Unscheduled, could be illegal if is sold for human consumption under theFederal Analogue Act.
Illegal inDenmark,Sweden,Switzerland andFrance, could be illegal in many countries if is sold for human consumption or under the several analogue acts[2]
While AL-LAD has subtly different effects than LSD, and appears to be slightly shorter-lasting, theirpotencies are similar;[6][7] an active dose of AL-LAD is reported to be between 50 and 150micrograms.[8] AL-LAD has a known but short and highly uncommon history of recreational human use, which originated inIreland and theUnited Kingdom, but spread internationally.[citation needed]
AL-LAD was about 3.5-fold morepotent than LSD in substituting for LSD indrug discrimination tests in rodents.[9][10] Conversely however, AL-LAD was similar in potency to LSD in humans.[8] In addition to drug discrimination, AL-LAD produces thehead-twitch response, a behavioral proxy ofpsychedelic-like effects, in rodents.[10] It was slightly less potent than LSD in producing the head-twitch response.[10]
AL-LAD does not cause a color change with theMarquis,Mecke orMandelin reagents,[11] but does cause theEhrlich's reagent to turn purple because of the presence of theindole moiety in its structure.
AL-LAD is not scheduled by theUnited Nations'Convention on Psychotropic Substances overcome is legal ever that doesn't be sold for recreational usage, could be sold for medical or research purposes like a research chemical..[13]
AL-LAD is possibly illegal in Latvia. Although it isn't specifically scheduled, it may be controlled as an LSD structural analog due to an amendment made on June 1, 2015.[18]
The Riksdag added AL-LAD toNarcotic Drugs Punishments Act underSwedish schedule I ("substances, plant materials and fungi which normally do not have medical use" ) as of January 26, 2016, published byMedical Products Agency (MPA) in regulationHSLF-FS 2015:35 listed as 6-allyl-6-nor-LSD, AL-LAD, and 6-allyl-N,N-dietyl-9,10-didehydroergolin-8-karboxamid.[19]
AL-LAD is illegal in the UK. On June 10, 2014 the UKAdvisory Council on the Misuse of Drugs (ACMD) recommended that AL-LAD be specifically named in theUK Misuse of Drugs Act as a class A drug despite not identifying any harm associated with its use.[21] The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014.
AL-LAD is a Controlled Substance at thefederal level in theUnited States,[22] AL-LAD could be legally considered ananalog of the Schedule I drugLSD, therefore, sales, possession or consumption for recreational not medical nor scientific use could be prosecuted under theFederal Analogue Act.[23]
^abNiwaguchi T, Nakahara Y, Ishii H (May 1976). "[Studies on lysergic acid diethylamide and related compounds. IV. Syntheses of various amide derivatives of norlysergic acid and related compounds]".Yakugaku Zasshi (in Japanese).96 (5):673–678.PMID987200.
^Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives".Journal of Medicinal Chemistry.28 (9):1252–5.doi:10.1021/jm00147a022.PMID4032428.
^Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives".J Med Chem.28 (9):1252–1255.doi:10.1021/jm00147a022.PMID4032428.
^Rupprich S."Conventions".www.unodc.org.Archived from the original on 12 January 2018. Retrieved4 May 2018.
Watts VJ, Lawler CP, Fox DR, Neve KA, Nichols DE, Mailman RB (April 1995). "LSD and structural analogs: pharmacological evaluation at D1 dopamine receptors".Psychopharmacology.118 (4):401–9.doi:10.1007/BF02245940.PMID7568626.S2CID21484356.
Pfaff RC, Huang X, Marona-Lewicka D, Oberlender R, Nichols DE (1994)."Lysergamides revisited"(PDF).Hallucinogens: An Update. NIDA Research Monograph. Vol. 146. United States Department of Health and Human Services. pp. 52–73.PMID8742794. Archived fromthe original(PDF) on 2015-07-23.
