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| Routes of administration | Oral |
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| Formula | C13H19N |
| Molar mass | 189.302 g·mol−1 |
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6-(2-Aminopropyl)tetralin (6-APT), also sometimes calledtetralinylaminopropane (TAP), is adrug of theamphetamine class which acts as aselective serotonin releasing agent (SSRA).[1] It hasIC50 values of 121 nM, 6,436 nM, and 3,371 nM forinhibiting thereuptake ofserotonin,dopamine, andnorepinephrine, respectively.[1] Though it possesses an appreciablein vitro profile, in animaldrug discrimination studies it was not found to substitute forMMAI oramphetamine and to only partially substitute forMBDB.[1] This parallelsAlexander Shulgin's finding thatEDMA (the1,4-benzodioxineanalogue of 6-APT) is limitedlyactive,[2] and appears to indicate that thepharmacokinetics of both EDMA and 6-APT may not be favorable.[1]
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