 | |
| Names | |
|---|---|
| Other names aldehyde-collidine, MEP, 5-Ethyl-2-picoline | |
| Identifiers | |
| |
3D model (JSmol) | |
| 109269 | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.002.955 |
| EC Number |
|
| RTECS number |
|
| UNII | |
| UN number | 2300 |
| |
| |
| Properties | |
| C8H11N | |
| Molar mass | 121.183 g·mol−1 |
| Appearance | colorless liquid |
| Density | 0.9208 g/cm3 |
| Melting point | −70.3 °C (−94.5 °F; 202.8 K) |
| Boiling point | 178 °C (352 °F; 451 K) |
| 1.2g/100 mL | |
| Hazards | |
| GHS labelling: | |
   | |
| Danger | |
| H302,H311,H314,H315,H317,H319,H331,H412 | |
| P260,P261,P264,P270,P271,P272,P273,P280,P301+P312,P301+P330+P331,P302+P352,P303+P361+P353,P304+P340,P305+P351+P338,P310,P311,P312,P321,P322,P330,P332+P313,P333+P313,P337+P313,P361,P362,P363,P403+P233,P405,P501 | |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
5-Ethyl-2-methylpyridine is anorganic compound with the formula (C2H5)(CH3)C5H3N. One of several isomericpyridines with this formula, this derivative is of interest because it is efficiently prepared from simple reagents and it is a convenient precursor tonicotinic acid, a form ofvitamin B3. 5-Ethyl-2-methylpyridine is a colorless liquid.[1]
5-Ethyl-2-methylpyridine is produced by condensation ofparaldehyde (a derivative ofacetaldehyde) andammonia:[2]
The conversion is an example of a structurally complex compound efficiently made from simple precursors. Under related conditions, the condensation of acetaldehyde and ammonia delivers2-picoline.
Oxidation of 5-ethyl-2-methylpyridine with nitric acid givesnicotinic acid via the decarboxylation of2,5-pyridinedicarboxylic acid.[1]
Like most alkylpyridines, theLD50 of 5-ethyl-2-methylpyridine is modest, being 368 mg/kg (oral, rat).[1]
