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3-ethylmalate synthase

From Wikipedia, the free encyclopedia
Class of enzymes
3-ethylmalate synthase
Identifiers
EC no.2.3.3.7
CAS no.9024-01-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDBPDBePDBsum
Gene OntologyAmiGO /QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

Inenzymology, a3-ethylmalate synthase (EC2.3.3.7) is anenzyme thatcatalyzes thechemical reaction

butanoyl-CoA + H2O + glyoxylate{\displaystyle \rightleftharpoons } 3-ethylmalate + CoA

The 3substrates of this enzyme arebutanoyl-CoA,H2O, andglyoxylate, whereas its twoproducts are3-ethylmalate andCoA.

This enzyme belongs to the family oftransferases, specifically thoseacyltransferases that convert acyl groups into alkyl groups on transfer. Thesystematic name of this enzyme class isbutanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming). Other names in common use include2-ethyl-3-hydroxybutanedioate synthase, and3-ethylmalate glyoxylate-lyase (CoA-butanoylating). This enzyme participates inglyoxylate and dicarboxylate metabolism.

References

[edit]
2.3.1: other than amino-acyl groups
2.3.2:Aminoacyltransferases
2.3.3: converted into alkyl on transfer
Activity
Regulation
Classification
Kinetics
Types
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