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2000 in sports describes the year's events in world sport.
Men's professional
Men's amateur
Women's professional
Steeplechases
Flat races
The following is a list of major noteworthy MMA events during 2000 in chronological order.
| Date | Event | Alternate Name/s | Location | Attendance | PPV Buyrate | Notes |
| January 30 | Pride Grand Prix 2000 Opening Round | — |  Tokyo, Japan | 48,316 | — | Opening Round to Pride GP 2000 openweight tournament. The event featuredRoyce Gracie in his first fight since April 1995. |
| March 10 | UFC 24: First Defense | — |  Lake Charles, Louisiana, United States | — | — | The event was originally scheduled to have a title fight betweenKevin Randleman andPedro Rizzo. However this postponed due to a concussion Randleman suffered before the fight. This event featured,Dan Severn as a referee for the preliminary bouts. |
| April 14 | UFC 25: Ultimate Japan 3 | — | Tokyo, Japan | — | — | This event was held to determine the new light heavyweight champion followingFrank Shamrock's retirement from the UFC. |
| May 1 | Pride Grand Prix 2000 Finals | — | Tokyo, Japan | 38,429 | — | Mark Coleman becomes the Pride 2000 openweight Grand Prix champion. The event featured a highly anticipated match betweenRoyce Gracie againstKazushi Sakuraba. |
| June 4 | Pride 9: New Blood | — | Nagoya, Japan | — | — | Matt Serra was to fight on this card, but his opponent, Johil de Oliveira, was injured by a pyrotechnics explosion at the event. |
| June 9 | UFC 26: Ultimate Field Of Dreams | — | Cedar Rapids, Iowa, United States | — | — | This event featured the first UFC "bantamweight" bout as defined as 155lbs. |
| August 27 | Pride 10 – Return of the Warriors | — | Tokorozawa, Saitama, Japan | 35,000 | — | — |
| September 22 | UFC 27: Ultimate Bad Boyz | — | New Orleans, United States | — | — | UFC veteranFrank Shamrock replacedJeff Blatnick in the announcers booth for this event. |
| October 31 | Pride 11 – Battle of the Rising Sun | — | Osaka, Japan | 13,500 | — | — |
| November 17 | UFC 28: High Stakes | — | Atlantic City, New Jersey, United States | — | — | UFC rule change,New Jersey SACB becomes the first state to regulate MMA in the USA. Uses newly writtenUnified Rules of Mixed Martial Arts. This event held the first and only UFC super heavyweight bout. |
| December 9 | Pride 12 – Cold Fury | — | Saitama, Japan | 26,882 | — | — |
| December 16 | UFC 29: Defense of the Belts | — | Tokyo, Japan | 1,414 | — | This was the last UFC event held by SEG. Because in January 2001, SEG sold the UFC to current ownersZuffa LLC. |