1492 was a year in the Julian calendar, most notable for being the year that Christopher Columbus sailed for America.

1492 may also refer to:

• 1492: Conquest of Paradise, a 1992 movie telling of Columbus's discovery of the new world
• 1492 epopea lirica d'America, an opera by Antonio Braga
• "1492" (song), a 2008 song by the band Counting Crows
• Papal conclave, 1492, a famous papal conclave that elected Alexander VI as Pope
• 1492 Pictures, a film production company owned by Chris Columbus
• 1492 Oppolzer, an asteroid

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