| Akagitsune | No | No | Yes | Yes | Yes | No | en-US | YuzuRyo61/Akagitsune on GitHub |
| Aria | Yes | Yes | Yes | Yes | Yes | No | Misskey supported languages | poppingmoon/aria on GitHub |
| BaconJam | No | Yes | No | No | No | No | ja? | - (Web Site) |
| Dhaaga | Soon™ | Yes | No | No | No | No | en, ja | suvam0451/dhaaga on GitHub |
| Flare | Testing | Yes | Work in progress | Work in progress | Work in progress | No | ar, cs, da, de, el, es, fi, fr, it, ja, nl,, no, pl, pt, pt-BR, ro, ru, sv, uk, zh-CN | DimensionDev/Flare on GitHub |
| Flosskey | No | Yes | No | No | No | No | ja-JP | ch1ak1STR/Flosskey on GitHub |
| Kimis | Yes | No | No | Yes | No | No | en-US | Lakr233/Kimis on GitHub |
| Milktea | No | Yes | No | No | No | No | en-US, ja-JP, zh-CN | pantasystem/Milktea on GitHub |
| minskey | No | No | No | No | No | Yes | ja? | yamader/minskey on GitHub |
| Mint | No | Testing | No | No | No | No | ja-JP | sanao1006/Mint on GitHub |
| Miria | Yes | Yes | Yes | Yes | Yes | No | ja-KS, ja-OJ | shiosyakeyakini-info/miria on GitHub |
| MissCat | Yes | No | No | No | No | No | ja? | YuigaWada/MissCat on GitHub |
| MissFARM | Yes | No | No | Yes | No | No | en | - |
| Misskey.io_MultiTimeLine (NOTMisskey.io Official) | No | No | No | No | No | Yes | ja? | yyya-nico/Misskey.io_MultiTimeline on GitHub |
| MissLI | No | No | No | No | No | Yes | ja? | uboar/missli on GitHub |
| Mizuna | No | No | No | No | No | Yes | ja-JP? | MizuiMiduki/Mizuna on GitHub |
| MoeKey | ? | Yes | Yes | Yes | Yes | ? | en-US, ja-JP, zh-CN | MoeKeyDev/MoeKey on GitHub |
| MPen | Yes | No | No | Yes | No | No | ja? | - |
| OpenTween | No | No | Yes | No | No | No | ja? | opentween/OpenTween on GitHub |
| Ore2 | Yes | No | No | Yes | No | No | ja-JP? | - |
| osukey | Yes(osu) | Yes(osu) | Yes(osu) | Yes(osu) | Yes(osu) | No | ja? | osukey/osukey on GitHub |
| PSkey | No | Yes | No | No | No | No | ja-JP | ibuki2003/pskey - GitHub |
| SoraSNS | Yes | No | No | Yes | No | No | fr, ja, kr, es, zh-CN, zh-TW | - |
| Takesama | Yes | Yes | No | Yes | No | Yes | ja? | - |
| TheDesk | No | No | Yes | Yes | Yes | No | ja? | cutls/thedesk-next on GitHub |
| TidyDrive | No | Yes | Yes | No | No | No | ja | - (Web Site) |
| TootRain | No | No | Yes | Yes | Yes(Beta) | No | en, ja | b123400/TootRain on GitHub /b123400/tootrain-qt on GitHub |
| ZonePane | No | Yes | No | No | No | No | ja-JP | - |