The finding that expressed emotion is associated with the course of psychiatric disorder has generated a great deal of clinical and research interest in expressed emotion as an important risk factor. Theoretical elucidation of the construct of expressed ...

January 1992

Are schizophrenia and affective disorder related? A selective literature review

Pages:22–32
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.22

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OBJECTIVE: Although most modern investigators accept the Kraepelinian view that schizophrenia and affective disorder are biologically distinct, others have suggested the psychoses are on a continuum of liability. This article is a selective review of ...

January 1992

Should caffeine abuse, dependence, or withdrawal be added to DSM-IV and ICD-10?

Pages:33–40
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.33

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OBJECTIVE: The authors reviewed basic science and clinical data on caffeine abuse, dependence, and withdrawal in order to make a conclusion about whether these disorders exist and should be included in DSM-IV and ICD-10. METHOD: Studies were located ...

January 1992

Attempted suicide among young adults: progress toward a meaningful estimate of prevalence

Pages:41–44
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.41

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OBJECTIVE: The results of epidemiologic surveys on attempted suicide are often difficult to interpret; they compare and provide varying estimates of the prevalence of attempted suicide. The authors sought to estimate the prevalence of attempted suicide in ...

January 1992

The relationship between adolescent suicidal behavior and life events in childhood and adolescence

Pages:45–51
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.45

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OBJECTIVE: Although the relationship between experience of problematic life events and adolescent suicidal behavior has frequently been recognized during the past decade, few studies of life events have been initiated that discriminated between adolescent ...

January 1992

Psychiatric correlates of incest in childhood

Pages:52–56
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.52

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OBJECTIVE: The purpose of the study was to describe more precisely the type of psychiatric illness associated with incest during childhood. METHOD: The Diagnostic Interview Schedule was administered to 52 adult women who had been victims of incest during ...

January 1992

Congenital malformations and structural developmental anomalies in groups at high risk for psychosis

Pages:57–61
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.57

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OBJECTIVE: Early somatic developmental anomalies may be one expression of a genetic influence toward psychosis. The purpose of this study was to investigate whether higher rates of early developmental anomalies are associated with heightened genetic risk ...

January 1992

Wisconsin Card Sorting Test performance in schizophrenia: remediation of a stubborn deficit

Pages:62–67
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.62

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OBJECTIVE: Schizophrenic patients typically perform poorly on the Wisconsin Card Sorting Test, which is a putative index of prefrontal functioning. The authors attempted to remediate the deficits of schizophrenic patients on this measure by giving ...

January 1992

Clozapine-induced weight gain: prevalence and clinical relevance

Pages:68–72
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.68

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OBJECTIVE: The aim of this study was to determine the prevalence and clinical relevance of weight gain during clozapine treatment. Previous reports indicated clinically significant weight gain in 13% to 85% of patients and an average gain of 9.0 to 24.7 ...

January 1992

Seasonal patterns of bulimia nervosa

Pages:73–81
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.73

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OBJECTIVE: The aim of this research was to determine whether a seasonal pattern to symptoms of bulimia nervosa could be identified. METHOD: In study 1, seasonal patterns of binge-purge frequency and mood were compared between 31 patients with bulimia ...

January 1992

Pharmacologic and cognitive-behavioral treatment for bulimia nervosa: a controlled comparison

Pages:82–87
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.82

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OBJECTIVE: This study examined the relative effectiveness of desipramine, cognitive-behavioral therapy, and their combination in the treatment of bulimia nervosa, together with the effects of withdrawing medication after two different lengths of ...

January 1992

Multiple personality disorder in Switzerland

Pages:88–92
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.88

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OBJECTIVE: There are no reliable data on the prevalence of multiple personality disorder. The objective of the study was to determine whether and, if so, how frequently patients with multiple personality disorder are encountered and diagnosed in ...

January 1992

Recovery and major depression: factors associated with twelve-month outcome

Pages:93–99
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.93

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OBJECTIVE: In spite of the prevalence and chronicity of major depression, there is no consensus regarding which clinical and psychosocial variables are associated with recovery. The authors examined the probability of recovery from a major depressive ...

January 1992

Anxiety syndromes as epiphenomena of primary major depression: outcome and familial psychopathology

Pages:100–107
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.100

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OBJECTIVE: Anxiety symptoms often appear within depressive episodes, but their significance is uncertain. This study sought to determine whether they indicate the coexistence of a separate disease process and whether they have prognostic significance. ...

January 1992

A double-blind comparison of valproate and lithium in the treatment of acute mania

Pages:108–111
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.108

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OBJECTIVE: This study was carried out to compare the efficacy of lithium carbonate with that of valproate in acute mania and to determine whether pretreatment clinical characteristics, such as the presence of a mixed affective state, might predict a ...

January 1992

DSM-IV and new diagnostic categories: holding the line on proliferation

Pages:112–117
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.112

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The authors discuss aspects of the decision-making process for including "new" diagnostic categories in DSM-IV. They detail the different kinds of new categories proposed for inclusion in DSM-IV and discuss the risks and benefits of incorporating them. ...

January 1992

Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients

Pages:118–120
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.118

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The authors measured intracellular Ca2+ concentrations in four manic and five bipolar depressed patients and seven comparison subjects. Platelet and lymphocyte intracellular Ca2+ concentrations were comparable. The patients' mean intracellular Ca2+ ...

January 1992

Verapamil versus lithium in acute mania

Pages:121–122
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.121

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Twenty acutely manic patients were studied in a double-blind randomized trial comparing verapamil with lithium. The Petterson Mania Scale, the Brief Psychiatric Rating Scale (BPRS), and the Clinical Global Impression (CGI) were administered before ...

January 1992

What is meant by the term "binge"?

Pages:123–124
Published Online:1 April 2006

https://doi.org/10.1176/ajp.149.1.123

Preview Abstract

Systematic examination of the use of the word "binge" by 243 young women revealed discrepancies between the lay and technical uses of the term; the young women placed great emphasis on loss of control and less on the quantity eaten. These discrepancies ...