American Journal of Psychiatry
Volume 175, Issue 3
March 2018
Cover: Black-capped Tanager (Tangara heinei) in La Tablaza, La Estrella, Antioquia, Colombia; taxonomy: P (rocnias) Heinei Cabanis, 1851 Colombia. Photo by Juan Guillermo Jaramill.
Editorials
March 2018
Cannabidiol, an Adjunct Player in the Antipsychosis Arsenal
- Anahita Bassir Nia,M.D.,
- Yasmin L. Hurd,Ph.D.
- Pages:197–198
- Published Online:1 March 2018
March 2018
A Geriatrics Perspective on Dementia Prevention and Treatment
- David C. Steffens,M.D., M.H.S.
- Pages:199–201
- Published Online:1 March 2018
March 2018
Internet-Based Psychotherapy: How Far Can We Go?
- James H. Kocsis,M.D.
- Pages:202–203
- Published Online:1 March 2018
March 2018
Corticotropin-Releasing Hormone Binding Protein: Stress, Psychopathology, and Antidepressant Treatment Response
- Ned H. Kalin,M.D.
- Pages:204–206
- Published Online:1 March 2018
Images in Psychiatry
March 2018
The Mental Health Mission Aboard the USNSComfort During Humanitarian Operations in Puerto Rico
- Stefan K. Schalk,Psy.D.,
- Steven R. Hendrix,B.S.,
- David A. Nissan,M.D.
- Pages:207–208
- Published Online:1 March 2018
Clinical Case Conference
AudioCME
March 2018Therapeutic Potential of Physical Exercise in Early Psychosis
- Douglas L. Noordsy,M.D.,
- Jonathan D. Burgess,B.A.,
- Kate V. Hardy,Clin.Psych.D.,
- Lynn M. Yudofsky,M.D.,
- Jacob S. Ballon,M.D., M.P.H.
- Pages:209–214
- Published Online:1 March 2018
Reviews and Overviews
AudioCME
March 2018Sensation and Psychiatry: Linking Age-Related Hearing Loss to Late-Life Depression and Cognitive Decline
- Bret R. Rutherford,M.D.,
- Katharine Brewster,M.D.,
- Justin S. Golub,M.D.,
- Ana H. Kim,M.D.,
- Steven P. Roose,M.D.
- Pages:215–224
- Published Online:5 December 2017
https://doi.org/10.1176/appi.ajp.2017.17040423
Preview Abstract
Recent research has linked age-related hearing loss to impaired performance across cognitive domains and increased risk for dementia diagnosis. The data linking hearing impairment to incident late-life depression are more mixed but suggest that diminished ...
Articles
AudioVideo
March 2018Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial
- Philip McGuire,F.R.C.Psych., F.Med.Sci.,
- Philip Robson,M.R.C.P., F.R.C.Psych.,
- Wieslaw Jerzy Cubala,M.D., Ph.D.,
- Daniel Vasile,M.D., Ph.D.,
- Paul Dugald Morrison,Ph.D., M.R.C.Psych.,
- Rachel Barron,B.Vet.Med., M.R.C.V.S.,
- Adam Taylor,Ph.D.,
- Stephen Wright,F.R.C.P.(Edin), F.F.P.M.
- Pages:225–231
- Published Online:15 December 2017
https://doi.org/10.1176/appi.ajp.2017.17030325
Preview Abstract
Objective:Research in both animals and humans indicates that cannabidiol (CBD) has antipsychotic properties. The authors assessed the safety and effectiveness of CBD in patients with schizophrenia.Method:In an exploratory double-blind parallel-group trial,...
AudioCME
March 2018Impact of SSRI Therapy on Risk of Conversion From Mild Cognitive Impairment to Alzheimer’s Dementia in Individuals With Previous Depression
- Claudia Bartels,Ph.D.,
- Michael Wagner,Ph.D.,
- Steffen Wolfsgruber,Ph.D.,
- Hannelore Ehrenreich,M.D.,
- Anja Schneider,M.D.,
- for the Alzheimer’s Disease Neuroimaging Initiative
- Pages:232–241
- Published Online:28 November 2017
https://doi.org/10.1176/appi.ajp.2017.17040404
Preview Abstract
Objective:Depression is associated with an increased risk of Alzheimer’s disease. Research has shown that the selective serotonin reuptake inhibitor (SSRI) citalopram decreases amyloid-β generation and plaque load. The authors evaluated the impact of SSRI ...
AudioVideo
March 2018Improving the Efficiency of Psychotherapy for Depression: Computer-Assisted Versus Standard CBT
- Michael E. Thase,M.D.,
- Jesse H. Wright,M.D., Ph.D.,
- Tracy D. Eells,Ph.D., M.B.A.,
- Marna S. Barrett,Ph.D.,
- Stephen R. Wisniewski,Ph.D.,
- G.K. Balasubramani,Ph.D.,
- Paul McCrone,Ph.D.,
- Gregory K. Brown,Ph.D.
- Pages:242–250
- Published Online:3 October 2017
https://doi.org/10.1176/appi.ajp.2017.17010089
Preview Abstract
Objective:The authors evaluated the efficacy and durability of a therapist-supported method for computer-assisted cognitive-behavioral therapy (CCBT) in comparison to standard cognitive-behavioral therapy (CBT).Method:A total of 154 medication-free ...
March 2018
Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein
- Chloe P. O’Connell,B.S.,
- Andrea N. Goldstein-Piekarski,Ph.D.,
- Charles B. Nemeroff,M.D., Ph.D.,
- Alan F. Schatzberg,M.D.,
- Charles Debattista,M.D.,
- Tania Carrillo-Roa,Ph.D.,
- Elisabeth B. Binder,M.D., Ph.D.,
- Boadie W. Dunlop,M.D.,
- W. Edward Craighead,Ph.D.,
- Helen S. Mayberg,M.D.,
- Leanne M. Williams,Ph.D.
- Pages:251–261
- Published Online:15 December 2017
https://doi.org/10.1176/appi.ajp.2017.17020172
Preview Abstract
Objective:Genetic variation within the hypothalamic-pituitary-adrenal (HPA) axis has been linked to risk for depression and antidepressant response. However, these associations have yet to produce clinical gains that inform treatment decisions. The ...
March 2018
Role of Complex Epigenetic Switching in Tumor Necrosis Factor-α Upregulation in the Prefrontal Cortex of Suicide Subjects
- Qingzhong Wang,Ph.D.,
- Bhaskar Roy,Ph.D.,
- Gustavo Turecki,M.D., Ph.D.,
- Richard C. Shelton,M.D.,
- Yogesh Dwivedi,Ph.D.
- Pages:262–274
- Published Online:24 January 2018
https://doi.org/10.1176/appi.ajp.2017.16070759
Preview Abstract
Objective:Proinflammatory cytokines have recently received considerable attention for their role in suicidal behavior; however, how the expression of cytokine genes is regulated is not clearly known. The authors examined underlying mechanisms of critical ...
March 2018
Clinical and Cognitive Significance of Auditory Sensory Processing Deficits in Schizophrenia
- Holly K. Hamilton,Ph.D.,
- Terrance J. Williams,Ph.D.,
- Joseph Ventura,Ph.D.,
- Leland J. Jasperse,B.A.,
- Emily M. Owens,M.A.,
- Gregory A. Miller,Ph.D.,
- Kenneth L. Subotnik,Ph.D.,
- Keith H. Nuechterlein,Ph.D.,
- Cindy M. Yee,Ph.D.
- Pages:275–283
- Published Online:5 December 2017
https://doi.org/10.1176/appi.ajp.2017.16111203
Preview Abstract
Objective:Although patients with schizophrenia exhibit impaired suppression of the P50 event-related brain potential in response to the second of two identical auditory stimuli during a paired-stimulus paradigm, uncertainty remains over whether this ...
Letters to the Editor
March 2018
Potential Impact of Medical Marijuana on Nonmedical Opioid Use
- Brandon M. Theriault,B.A.,
- Joseph J. Schlesinger,M.D.
- Page:284
- Published Online:1 March 2018
March 2018
Medical Marijuana and the Opioid Epidemic: Response to Theriault and Schlesinger
- Mark Olfson,M.D., M.P.H.,
- Melanie M. Wall,Ph.D.,
- Carlos Blanco,M.D., Ph.D.
- Pages:284–285
- Published Online:1 March 2018
March 2018
Suicide Rates, Psychiatric Hospital Bed Numbers, and Unemployment Rates From 1999 to 2015: A Population-Based Study in Hong Kong
- Edwin Ho Ming Lee,M.Sc., M.B.Ch.B.,
- Christy Lai Ming Hui,Ph.D.,
- Pik Ying Chan,M.Sc.,
- Wing Chung Chang,M.B.Ch.B.,
- Sherry Kit Wa Chan,M.Phil., M.B.B.S.,
- Eric Yu Hai Chen,M.D.
- Pages:285–286
- Published Online:1 March 2018
March 2018
Understanding Pregnancy’s Protective Effect on Drug Use Within a Developmental Framework
- Suena H. Massey,M.D.,
- Katherine L. Wisner,M.D., M.S.
- Pages:286–287
- Published Online:1 March 2018
Book Forum
March 2018
Psychiatrists in Combat: Mental Health Clinicians’ Experiences in the War Zone
- Sheila Hafter Gray,M.D.
- Pages:288–289
- Published Online:1 March 2018
March 2018
Treating Sleep Problems: A Transdiagnostic Approach
- Thomas Mellman,M.D.
- Pages:289–290
- Published Online:1 March 2018