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AJP Audio brings you highlights from each issue ofThe American Journal of Psychiatry. Discover morepodcasts produced by the American Psychiatric Association.
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- March 2019: Self-Harm and Violent Crime
Executive Editor Michael Roy speaks with Leah S. Richmond-Rakerd, Ph.D., about her research on the antecedents, clinical features, and life characteristics of adolescents who engage in bothself-harming and violent criminal behaviors.
February 2019: Substance UseExecutive Editor Michael Roy speaks with Patricia J. Conrod, Ph.D., about her research on the relationship betweensubstance use and adolescent cognitive development. Deputy Editor Kathleen T. Brady, M.D., Ph.D., discusses her editorial onimproving our understanding of substance use disorders.
January 2019: Introducing New Editor-in-Chief Ned Kalin, M.D.Ned Kalin, M.D., begins his term as Editor-in-Chief of theJournal. Speaking with Executive Editor Michael Roy, Dr. Kalinoutlines his vision for his tenure and discusses the kinds of research that will appear in theJournal.
December 2018
Download audio file(mp3, 31:19 min, 34.7 MB)Outgoing Editor-in-Chief Robert Freedman, M.D.,reflects on his tenure as Editor of theJournal. Executive Editor Michael Roy reviews research on the management ofvascular depression, the use of prazosin foralcohol use disorder, and how maternal severe mental illness and exposure to obstetric complications are associated withintellectual disability and psychotic disorders in children.
November 2018
Download audio file(mp3, 14:30 min, 16.3 MB)Host Ann Thomas talks with Alan S. Brown, M.D., M.P.H., about his research on the association of maternal insecticide levels withautism, and on maternal immune activation andneuropsychiatric illness. Executive Editor Michael Roy reviews research on howsmoking affects cognitive functioning, a randomized controlled trial ofparent-child psychotherapy, and challenges in managing mental health problems intransgender individuals.
October 2018
Download audio file(mp3, 25:39 min, 26.6 MB)Executive Editor Michael Roy talks with Jill E. Bormann, Ph.D., R.N., about her research onmantram repetition therapy to treat PTSD in veterans. Other highlights: howinsight affects outcome in psychotherapy, how medications for addictive behaviors affectcrime and suicide, how electronic health records can be used topredict suicide attempts, and the mental health impact ofviolence toward targeted populations.
September 2018
Download audio file(mp3, 22:45 min, 26.9 MB)Executive Editor Michael Roy talks with Betsy D. Kennard, Psy.D., about her research on aninpatient intervention and smartphone app to reduce adolescent suicide attempts following hospital discharge. Other highlights: care of patients withnonepileptic seizures; howsudden parental death affects depression in children;computerized CBT for addiction treatment; and the relationship betweenabortion and suicidal ideation.
August 2018
Download audio file(mp3, 21:55 min, 24.9 MB)Host Ann Thomas talks with Wilson M. Compton, M.D., M.P.E., about his research on patterns ofmisuse of prescription stimulant medication in the United States. Executive Editor Michael Roy reviewsburnout among physicians, whether depression causespremature aging, discontinuation ofantipsychotic treatment in schizophrenia, and risk ofpostpartum psychiatric episodes.
July 2018
Download audio file(mp3, 27:13 min, 30.1 MB)Executive Editor Michael Roy talks with M. Camille Hoffman, M.D., about her research on the use ofnutritional supplements in pregnancy. Michael Roy also speaks with Daniel S. Pine, M.D., Deputy Editor of theJournal, about a clinical trial involvingketamine and whether aframework can be established for the safe use of ketamine. Other highlights: howphysical activity can affect depression, andtreatment of alcohol-dependent adults who are involved with the criminal justice system.
June 2018
Download audio file(mp3, 26:53 min, 29.5 MB)Executive Editor Michael Roy talks with Avshalom Caspi, Ph.D., about his research on the relationship between early-life stress and later changes inDNA methylation. Other highlights: a unique form ofepisodic psychosis, health care use before anopioid-related death, new genetic markers fordepression, and the effect of antipsychotic medication on therisk for diabetes in pregnancy.
May 2018
Download audio file(mp3, 17:37 min, 18.5 MB)Executive Editor Michael Roy talks with Kelly K. Anderson, Ph.D., about her research on the effectiveness ofearly psychosis intervention programs. Other highlights: early-onset dementia in a patient with22q11 deletion syndrome and Huntington’s disease, early intervention inbipolar disorder, a novel memory-based therapy withpropranolol to reduce PTSD symptoms, andpatterns of health care use prior to first diagnosis of a psychotic disorder.
April 2018
Download audio file(mp3, 27:36 min, 31.3 MB)Executive Editor Michael Roy speaks with Edith V. Sullivan, Ph.D., and Adolf Pfefferbaum, M.D., of Stanford University about their article investigating how drinking affects the development of theadolescent brain. Other highlights: how long theeffects of ketamine can last, trends associated withsubstance-induced psychosis, the relationship betweenhormonal contraception and suicide, and treatment for patients withconversion disorder.
March 2018
Download audio file(mp3, 21:48 min, 24.2 MB)Executive Editor Michael Roy talks with Philip McGuire, F.R.C.Psych., F.Med.Sci., about his research oncannabidiol as an adjunctive therapy in schizophrenia. Other highlights: the relationship betweenage-related hearing loss and cognitive decline; how long-term SSRI treatment may delayprogression from mild cognitive impairment to Alzheimer’s dementia; comparingcomputer-assisted cognitive-behavioral therapy (CBT) with standard CBT; and thevalue of exercise in early psychosis.
February 2018
Download audio file(mp3, 17:11 min, 19.2 MB)Executive Editor Michael Roy speaks with Margaret Sibley, Ph.D., about her article examining thediagnosis of late-onset ADHD. Other highlights:bright light therapy for bipolar depression; how well asingle dose of ketamine reduced suicidal thoughts in patients with depression; a roadmap forunderstanding neurodevelopmental origins of conditions that manifest in early childhood; andprolonged postconcussive symptoms.
January 2018
Download audio file(mp3, 22:54 min, 23.0 MB)Editor-in-Chief Robert Freedman, M.D., discusses the175th publication year of theJournal. Executive Editor Michael Roy reviewsrefugee mental health issues,exercise and the prevention of depression,cannabis use and risk of prescription opioid use disorder, andincreased risk of smoking in female adolescents who had childhood ADHD.
December 2017
Download audio file(mp3, 17:02 min, 19.3 MB)This month, Executive Editor Michael Roy discussesbrain function and psychotherapy outcomes in patients with PTSD,transgender research from a neurocognitive angle, research results ofa new drug for schizophrenia, andcharacteristics of resilience in bipolar disorder and how individuals who are bipolarexperience the world.
November 2017
Download audio file(mp3, 14:40 min, 15.4 MB)This month, Deputy Editor Susan K. Schultz, M.D., discussesclinical genetic testing in psychiatry, binge drinking as a possible risk factor foralcohol use disorder, lithium versus divalproex forbipolar disorder in the elderly, thecourse of schizophrenia over the first 20 years, as well astrajectories of social functioning over 20 years.
October 2017
Download audio file(mp3, 14:27 min, 15.0 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusses theefficacy of psychodynamic therapy, theprotective effect of pregnancy on the risk for drug abuse, therelation of ovarian hormone levels to symptoms in premenstrual dysphoric disorder, rates ofmortality and self-harm in patients taking clozapine, andpharmacogenomic testing in psychiatry.
September 2017
Download audio file(mp3, 16:57 min, 18.0 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusseschallenges in treating undocumented immigrants, long-term effects ofantipsychotics in schizophrenia, whethersubstance use problems are associated with medications for ADHD,use of Social Security disability benefits by patients with first-episode psychosis receiving multifaceted specialty care, a largegenome-wide association study of anorexia nervosa, andwhen and why medical students choose to specialize in psychiatry.
August 2017
Download audio file(mp3, 17:42 min, 16.2 MB)This month, Deputy Editor Susan K. Schultz, M.D., discussessmartphones for self-management in schizophrenia, behavioral interventions inbuprenorphine maintenance treatment,suicide following self-harm, effects of lithium and valproate on suicidal behavior inbipolar disorder, treatment ofpediatric anxiety disorders with cognitive-behavioral-therapy (CBT) plus attention bias modification therapy,treatment of hypochondriasis with CBT plus medication, and treatment of major depression withamygdala neurofeedback.
July 2017
Download audio file(mp3, 16:06 min, 14.7 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusses psychiatric complications inprimary parathyroidism with hypercalcemia, low-intensitytranscranial current stimulation for psychiatric conditions, outcomes ofvagus nerve stimulation for treatment-resistant depression, brain structure and function related tosuicide attempts in young people with bipolar disorder, endogenous and medication-related risk fordiabetes in schizophrenia, andgaze-contingent music reward therapy for social anxiety disorder.
June 2017
Download audio file(mp3, 15:20 min, 14.0 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusses patient preference and functional connectivity of the subcallosal cingulate cortex as possible predictors of treatment response in major depression, a behavioral phenotype of autism spectrum disorder characteristic of patients with known genetic abnormalities, functioning of the brain’s reward system in anorexia nervosa, collaboration between psychiatry and law enforcement, and a model of irritability in children and teens.
May 2017
Download audio file(mp3, 14:54 min, 16.1 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusses antidepressant efficacy for depression in children and adolescents, morbidity and mortality related to medications for depression, possible benefits of valbenazine for tardive dyskinesia, opioid detoxification using oral naltrexone versus buprenorphine, and the relation of divorce to the onset of alcohol use disorders.
April 2017
Download audio file(mp3, 15:45 min, 16.6 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusses the fetal origins of mental health, the effect of methylphenidate on the risk of manic episodes in bipolar disorder, contingency management for alcohol abuse in patients with serious mental illness, computerized cognitive training for older adults with mild cognitive impairment or dementia, prediction of relapse in Alzheimer’s disease patients after discontinuation of antipsychotic treatment, and the origins of cognitive deficits in people victimized during childhood.
March 2017
Download audio file(mp3, 12:25 min, 22.7 MB)This month, Executive Editor Michael Roy discusses collaboration between psychiatry and obstetrics, prescription opioid use disorder during pregnancy, integrated behavioral health homes, a possible relationship between Alzheimer’s disease and low hippocampal volume in late-life depression, switch rates during lithium and sertraline treatment of bipolar II depression, internet gaming disorder, and the relation of mental health to social networks following disaster.
February 2017
Download audio file(mp3, 12:32 min, 22.9 MB)This month, Executive Editor Michael Roy discusses use of stimulants and performance enhancers as a possible risk factor for PTSD, behavioral and brain markers of overgeneralized fear conditioning in PTSD, the epidemiology of first-episode psychosis, predictors of suicidal behavior, neural predictors of initiating alcohol use during adolescence, and mediation of placebo effects by patient expectancy in antidepressant clinical trials.
January 2017
Download audio file(mp3, 16:10 min, 14.8 MB)This month, Deputy Editor Susan K. Schultz, M.D., discusses the association of hypnotic medications and suicide, neurometabolic disorders in treatment-refractory depression, diminished attention to eyes in autism, increased activity or energy as a primary criterion for diagnosis of bipolar mania, an instrument for diagnosing premenstrual dysphoric disorder, and how to differentiate the effects of deep brain stimulation in Parkinson’s disease from the effects of the disease itself and psychiatric issues.
December 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses combat attachment behaviors in former service members with PTSD, postpartum psychosis, the association between pain and opioid use disorder, work productivity in relation to depression outcome, neural response to rewards as a predictor of depression, and adjustment disorder following trauma exposure.
November 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses practice and policies on perinatal substance abuse, relapse risk in patients with remitted depression, right unilateral ultrabrief-pulse ECT combined with medication in acute and maintenance geriatric depression, suicide risk calculated prospectively in a population cohort, and a new approach to fear and anxiety that takes into account both behavioral responses and conscious feeling states.
October 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses research on preventing firearm suicide, treatment guidelines for adult attention deficit hyperactivity disorder, long-term effects of supported employment for people with psychiatric disabilities, predicting psychosis risk in individuals with prodromal symptoms, how often psychotic experiences precede mental disorders and vice versa, and a 30-year follow-up study of offspring of depressed parents.
September 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses the diagnosis and treatment of trichotillomania, combining antidepressants with antipsychotics in schizophrenia, outcomes of the FDA reduction in the citalopram maximum dosage, heritable and nonheritable pathways to early callous and unemotional behaviors, and the effect of marriage on the risk for alcohol use disorder.
August 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses accelerometers in diagnosis and treatment of late-life depression, concomitant use of SSRIs and statins, treatment of cognitive impairment in schizophrenia with an alpha-7 nicotinic receptor agonist, the relation of adolescent marijuana use to subclinical psychotic symptoms and to mortality at age 60, and the effect of nicotine exposure during pregnancy to development of schizophrenia in offspring.
July 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses how psychiatrists can extend their role to treatment of general health conditions, how to evaluate randomized clinical trials, interpersonal psychotherapy for mental health problems, fluidity of symptoms in borderline personality disorder, predictors of bipolar illness in offspring of bipolar parents, and the relation of prenatal maternal distress to fetal behavior and to DNA changes in glucocorticoid-related genes in the placenta.
June 2016:Listen
This month, Executive Editor Michael Roy discusses nutrient-based treatments as adjuncts to antidepressants, the prevalence and characteristics of cannabis use disorder as defined in DSM-5, long-term mortality rates in women with severe postpartum psychiatric disorders, a program for children in foster care and their biological parents designed to prevent repetition of childhood maltreatment, whether the relationship between preschool poverty and school-age depression is mediated by functional brain connectivity, and the NIMH Research Domain Criteria project.
May 2016:Listen
This month, Executive Editor Michael Roy discusses a generalist model for treatment of borderline personality disorder, citalopram treatment for agitated patients with Alzheimer’s dementia, buprenorphine for severe suicidal ideation and as an adjunctive treatment in cases of antidepressant nonresponse, effects of prenatal choline supplementation on early-childhood behavior problems, and mechanisms of executive system dysfunction across psychiatric disorders in youths.
April 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses lurasidone for major depression with mixed features, bitemporal ECT compared with high-dose unilateral ECT given twice a week, neurocircuitry of depression with increased versus decreased appetite, attenuated psychosis syndrome, identification of distinct psychosis biotypes, and comprehensive community care for first-episode psychosis.
March 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses depression following stroke, cerebral abnormalities in patients with first-episode schizophrenia, risks of poorly monitored ketamine use for depression, long-term outcomes of light therapy versus CBT for seasonal affective disorder, the reproductive safety of second-generation antipsychotics, and the effects of antipsychotic review and nonpharmacological interventions on antipsychotic use, symptoms, and mortality in nursing home residents.
February 2016:Listen
This month, Executive Editor Michael Roy discusses the risk of postpartum relapse in bipolar disorder and postpartum psychosis, the relation of pregnant women’s defense mechanisms to later behavior in their toddlers, sequential integration of pharmacotherapy and psychotherapy for depression, the dose-response relationship of SSRIs, the effectiveness of clozapine versus standard antipsychotic treatment for schizophrenia, and the relation of prenatal maternal depression, SSRIs, and benzodiazepines to infant neurobehavioral functioning.
January 2016:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses a request for abortion by a woman with major depression and psychosis, prescription opioid abuse and its treatment, questions about MRI findings of neuropathology underlying psychiatric illness, predicting response to antipsychotic drugs from baseline striatal functional connectivity, the association between obesity and ADHD, and amygdala hyperactivity during autobiographical recall as a possible trait marker of depression.
December 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses management of alcohol use disorder in patients requiring liver transplant, adding ziprasidone to escitalopram for treatment of depression, attention training for reducing PTSD symptoms, extended-release guanfacine for hyperactivity in autism spectrum disorder, a program for preventing anxiety disorders in offspring of anxious parents, and pregnancy complications following prenatal exposure to SSRIs or maternal psychiatric disorders.
November 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses psychiatric symptoms in Wilson’s disease, interactions between inflammation and depression, circulating miRNA levels in schizophrenia, the relation of smoking status to later schizophrenia, development of posttraumatic stress disorder in Army service members following traumatic brain injury, and working in the Amish culture.
October 2015:Listen
This month, Executive Editor Michael Roy discusses ketamine and other NMDA antagonists as treatments for depression, a gene-environment interaction affecting depression risk, a longitudinal study of ADHD in children and adults, a follow-up of adolescents at clinical high risk of psychosis, and a clinical trial of citicoline for cocaine dependence in bipolar I disorder.
September 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses differential diagnosis of frontotemporal dementia, autoimmune encephalitis in postpartum psychosis, the role of oxytocin in borderline personality disorder, neural correlates of error processing in young people exposed to severe childhood abuse, light therapy versus cognitive-behavioral therapy for seasonal affective disorder, and cognitive enhancement treatment for people with mental illness who do not respond to supported employment.
August 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses the role of the psychiatrist in the collaborative care model, pharmacological management of Lewy body dementia, the relationship of depression subtype to antidepressant response, amygdala activity at rest in paranoid individuals with schizophrenia, and use of clonidine in opioid abstinence to prolong abstinence and decouple stress from craving in daily life.
July 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses diagnostic precursors of bipolar disorder in offspring of bipolar parents, intergenerational transmission of anxiety in the children of twins, separation anxiety disorder in children and adults, genetic and environmental influences on irritability from childhood to young adulthood, and the relation of impaired response inhibition to neural activation in adolescents with ADHD, their siblings, and healthy subjects.
June 2015:Listen
This month, Executive Editor Michael Roy discusses psychiatric care during hepatitis C treatment with the new direct-acting antivirals, cognitive-behavioral therapy for anxiety disorders in adolescents, brain development over time in adolescents who are heavy drinkers, a genetic polymorphism related to early escalation of drinking and to impulsivity, how working memory is related to the ratio of serum levels of clozapine and its major metabolite, and a clinical trial testing the combination of citalopram and methylphenidate for geriatric depression.
May 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses narcissistic personality disorder, interpersonal psychotherapy for PTSD, brief cognitive-behavioral therapy to reduce suicide attempts in high-risk military personnel, effects on children of their mothers’ response to antidepressant medication, and the relation of autistic traits to neuroanatomy in the general population.
April 2015:Listen
This month, Deputy Editor Susan Schultz discusses an innovative study that used an algorithm to search electronic health records for clinical information relevant to the Research Domain Criteria; potentially modifiable conditions that predict a transition from mild cognitive impairment to dementia; a trial of cognitive-bias modification to reduce reactivity to alcohol cues in patients with alcohol dependence; a clinical trial that added health coaching to fitness club membership for overweight persons with serious mental illness; and an intriguing short essay about correspondence between Charles Darwin and the head gardener at an English mental institution.
March 2015:Listen
This month, Executive Editor Michael Roy discusses adjustment disorder in a health care worker with Ebola, a case of psychotic symptoms that improved with a gluten-free diet, medication prescribing for first-episode schizophrenia, outcomes for young people at ultra-high risk for psychosis who do not transition to psychotic disorders, possible mechanisms in perimenopausal depression, and change during adolescence in reactivity of the amygdala in relation to stressful life events and family history of depression.
February 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses treatment for postpartum psychosis and mania, a home-visiting intervention for pregnant teenage American Indian mothers, brain patterns underlying learning deficits in autism spectrum disorders, an approach to the genetics of schizophrenia focusing on clusters of genetic variants and clusters of clinical features, and effects of the Affordable Care Act’s expansion of insurance for young adults on rates of hospital admissions and emergency department visits.
January 2015:Listen
This month, Deputy Editor Susan K. Schultz, M.D., discusses hypercalcemia and hyperparathyroidism during lithium therapy, a weight loss intervention tailored to individuals taking antipsychotic medications, the effect of socioeconomic disadvantage on outcome of collaborative depression care in OB-GYN clinics, ECT for treatment-resistant bipolar depression, ECT for clozapine-resistant schizophrenia, and the relation of an intervention for kindergartners with chronic conduct problems to psychopathology and crime at age 25.



