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Psychiatry Online
Sections

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cover

American Journal of Psychiatry

Volume 165, Issue 4

THE AMERICAN JOURNAL OF PSYCHIATRY April 2008 Volume 165 Number 4

April 2008
In This Issue
Editorial
Commentary
Reviews and Overviews
April 2008
Neurobiology of Aggression and Violence
  • Pages:429–442
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2008.07111774

Preview Abstract
Acts of violence account for an estimated 1.43 million deaths worldwide annually. While violence can occur in many contexts, individual acts of aggression account for the majority of instances. In some individuals, repetitive acts of aggression are ...
Introspections
Education in Psychiatry
Clinical Case Conference
Images in Psychiatry
Article
April 2008
Fluoxetine Versus Placebo in Preventing Relapse of Major Depression in Children and Adolescents
  • Pages:459–467
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07091453

Preview Abstract
Objective: The authors compared fluoxetine and placebo in continuation treatment to prevent relapse of major depressive disorder in children and adolescents. Method: After a detailed evaluation, children and adolescents 7–18 ...
April 2008
Systems Training for Emotional Predictability and Problem Solving (STEPPS) for Outpatients With Borderline Personality Disorder: A Randomized Controlled Trial and 1-Year Follow-Up
  • Pages:468–478
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07071079

Preview Abstract
Objective: Systems Training for Emotional Predictability and Problem Solving (STEPPS) is a 20-week manual-based group treatment program for outpatients with borderline personality disorder that combines cognitive behavioral elements and skills ...
April 2008
Conserved Regional Patterns of GABA-Related Transcript Expression in the Neocortex of Subjects With Schizophrenia
  • Pages:479–489
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07081223

Preview Abstract
Objective: Individuals with schizophrenia exhibit disturbances in a number of cognitive, affective, sensory, and motor functions that depend on the circuitry of different cortical areas. The cognitive deficits associated with dysfunction of the ...
April 2008
Excessive Brain Volume Loss Over Time in Cannabis-Using First-Episode Schizophrenia Patients
  • Pages:490–496
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07071110

Preview Abstract
Objective: Cerebral gray matter volume reductions have been found to progress over time in schizophrenia, with larger decreases related to poorer outcome, which has also been associated with cannabis use in schizophrenia patients. Progressive ...
April 2008
No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics
  • Pages:497–506
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07101573

Preview Abstract
Objective: The authors carried out a genetic association study of 14 schizophrenia candidate genes (RGS4, DISC1, DTNBP1, STX7, TAAR6, PPP3CC, NRG1, DRD2, HTR2A, DAOA, AKT1, CHRNA7, COMT , andARVCF ). ...
April 2008
Association of Low Striatal Dopamine D2 Receptor Availability With Nicotine Dependence Similar to That Seen With Other Drugs of Abuse
  • Pages:507–514
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07020352

Preview Abstract
Objective: All drugs of abuse induce a phasic dopamine release within the striatum that does not undergo habituation. Prolonged substance consumption impairs the natural function of the mesolimbic dopamine system, as shown by a decrease in the ...
April 2008
Depression and Ischemic Heart Disease Mortality: Evidence From the EPIC-Norfolk United Kingdom Prospective Cohort Study
  • Pages:515–523
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07061018

Preview Abstract
Objective: The authors investigated the association between major depressive disorder, including its clinical course, and mortality from ischemic heart disease. Method: This was a prospective cohort study of 8,261 men and 11,...
April 2008
Regional White Matter Hyperintensity Burden in Automated Segmentation Distinguishes Late-Life Depressed Subjects From Comparison Subjects Matched for Vascular Risk Factors
  • Pages:524–532
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2007.07010175

Preview Abstract
Objective: Segmented brain white matter hyperintensities were compared between subjects with late-life depression and age-matched subjects with similar vascular risk factor scores. Correlations between neuropsychological performance and whole ...
Letters to the Editor
Correction
April 2008
Correction
  • Page:540
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2008.165.4.540

Book Forum
Books Received
April 2008
Books Received
  • Page:544
  • Published Online:1 April 2008

https://doi.org/10.1176/appi.ajp.2008.165.4.544

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