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Psychiatry Online
Sections

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cover

American Journal of Psychiatry

Volume 166, Issue 2

THE AMERICAN JOURNAL OF PSYCHIATRY February 2009 Volume 166 Number 2

February 2009
In This Issue
February 2009
In This Issue
  • Page:A18
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2009.166.2.A18

Editorial
Commentary
Treatment in Psychiatry
Images in Psychiatry
Reviews and Overviews
February 2009
A Meta-Analysis of Head-to-Head Comparisons of Second-Generation Antipsychotics in the Treatment of Schizophrenia
  • Pages:152–163
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08030368

Preview Abstract
Objective: Whether there are differences in efficacy among second-generation antipsychotics in the treatment of schizophrenia is a matter of heated debate. The authors conducted a systematic review and meta-analysis of blinded studies comparing ...
Article
February 2009
Manic Symptoms During Depressive Episodes in 1,380 Patients With Bipolar Disorder: Findings From the STEP-BD
  • Pages:173–181
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08050746

Preview Abstract
Objective: Little is known about how often bipolar depressive episodes are accompanied by subsyndromal manic symptoms in bipolar I and II disorders. The authors sought to determine the frequency and clinical correlates of manic symptoms during ...
February 2009
Older Adults’ Attitudes Toward Enrollment of Non-competent Subjects Participating in Alzheimer’s Research
  • Pages:182–188
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08050645

Preview Abstract
Objective: Research that seeks to enroll noncompetent patients with Alzheimer’s disease without presenting any potential benefit to participants is the source of substantial ethical controversy. The authors used hypothetical Alzheimer’s disease ...
February 2009
Neuropsychological Near Normality and Brain Structure Abnormality in Schizophrenia
  • Pages:189–195
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08020258

Preview Abstract
Objective: Cognitive deficits are prominent in schizophrenia. Patients have an average score one standard deviation below normal on a broad spectrum of cognitive tests. It has been repeatedly noted, however, that 20%–25% of patients differ from ...
February 2009
Association of Cerebral Deficits With Clinical Symptoms in Antipsychotic-Naive First-Episode Schizophrenia: An Optimized Voxel-Based Morphometry and Resting State Functional Connectivity Study
  • Pages:196–205
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08020183

Preview Abstract
Objective: The purpose of the present study was to characterize the association between clinical symptoms and anatomical and functional cerebral deficits in a relatively large sample of antipsychotic-naive first-episode schizophrenia patients ...
February 2009
Strong Evidence for a Novel Schizophrenia Risk Locus on Chromosome 1p31.1 in Homogeneous Pedigrees From Tamil Nadu, India
  • Pages:206–215
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08030442

Preview Abstract
Objective: The study of ethnically homogeneous populations may help to identify schizophrenia risk loci. The authors conducted a genomewide linkage scan for schizophrenia in an Indian population. Method: Participants were ...
February 2009
Evidence That Altered Amygdala Activity in Schizophrenia Is Related to Clinical State and Not Genetic Risk
  • Pages:216–225
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.08020261

Preview Abstract
Objective: Although amygdala dysfunction is reported in schizophrenia, it is unknown whether this deficit represents a heritable phenotype that is related to risk for schizophrenia or whether it is related to disease state. The purpose of the ...
February 2009
An Odor-Specific Threshold Deficit Implicates Abnormal Intracellular Cyclic AMP Signaling in Schizophrenia
  • Pages:226–233
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2008.07071210

Preview Abstract
Objective: Although olfactory deficits are common in schizophrenia, their underlying pathophysiology remains unknown. Recent evidence has suggested that cAMP signaling may be disrupted in schizophrenia. Since cAMP mediates signal transduction ...
Letters to the Editor
Correction
February 2009
Correction
  • Pages:237–238
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2009.166.2.237

Letters to the Editor
Correction
February 2009
Correction
  • Page:238
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2009.166.2.238

Book Forum
Books Received
February 2009
Books Received
  • Page:244
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2009.166.2.244

APA Official Actions
February 2009
APA Official Actions
  • Pages:245–258
  • Published Online:1 February 2009

https://doi.org/10.1176/appi.ajp.2009.166.2.245

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