American Journal of Psychiatry
Volume 175, Issue 2
February 2018
Cover: Dorothy Sit et al. (p. 131), in a randomized, double-blind, placebo-controlled trial, found that bright light therapy, in combination with antimanic medication, improves symptoms of depression in adults with bipolar I or bipolar II disorder. (Image by Conrado, Shutterstock.com).
Editorials
February 2018
Growing Up: Evolving Concepts of Adult Attention Deficit Hyperactivity Disorder
- Philip Shaw,B.M., B.Ch., Ph.D.
- Pages:95–96
- Published Online:1 February 2018
February 2018
Antisuicidal Effects of Ketamine: A Promising First Step
- Madhukar H. Trivedi,M.D.
- Pages:97–98
- Published Online:1 February 2018
February 2018
Why Apathy in Alzheimer’s Matters
- David L. Sultzer,M.D.
- Pages:99–100
- Published Online:1 February 2018
February 2018
Optimizing the Pharmacologic Treatment of Individuals With First-Episode Psychosis
- Donald C. Goff,M.D.
- Pages:101–102
- Published Online:1 February 2018
Treatment in Psychiatry
AudioCME
February 2018Prolonged Postconcussive Symptoms
- Davin K. Quinn,M.D.,
- Andrew R. Mayer,Ph.D.,
- Christina L. Master,M.D.,
- Jesse R. Fann,M.D., M.P.H.
- Pages:103–111
- Published Online:1 February 2018
Perspectives in Global Mental Health
February 2018
The “Loss of Pride” Syndrome in Yazidi Refugees
- Rami Bou Khalil,M.D., M.Sc.,
- Ana Guimaraes,M.A.,
- Sami Richa,M.D., Ph.D.
- Pages:112–113
- Published Online:1 February 2018
Reviews and Overviews
AudioCME
February 2018The Neurodevelopmental Basis of Early Childhood Disruptive Behavior: Irritable and Callous Phenotypes as Exemplars
- Lauren S. Wakschlag,Ph.D.,
- Susan B. Perlman,Ph.D.,
- R. James Blair,Ph.D.,
- Ellen Leibenluft,M.D.,
- Margaret J. Briggs-Gowan,Ph.D.,
- Daniel S. Pine,M.D.
- Pages:114–130
- Published Online:17 November 2017
https://doi.org/10.1176/appi.ajp.2017.17010045
Preview Abstract
The arrival of theJournal's 175th anniversary occurs at a time of recent advances in research, providing an ideal opportunity to present a neurodevelopmental roadmap for understanding, preventing, and treating psychiatric disorders. Such a roadmap is ...
Articles
AudioCME
February 2018Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial
- Dorothy K. Sit,M.D.,
- James McGowan,B.A.,
- Christopher Wiltrout,B.S.,
- Rasim Somer Diler,M.D.,
- John (Jesse) Dills,M.L.S.,
- James Luther,M.A.,
- Amy Yang,M.S.,
- Jody D. Ciolino,Ph.D.,
- Howard Seltman,M.D., Ph.D.,
- Stephen R. Wisniewski,Ph.D.,
- Michael Terman,Ph.D.,
- Katherine L. Wisner,M.D., M.S.
- Pages:131–139
- Published Online:3 October 2017
https://doi.org/10.1176/appi.ajp.2017.16101200
Preview Abstract
Objective:Patients with bipolar disorder have recurrent major depression, residual mood symptoms, and limited treatment options. Building on promising pilot data, the authors conducted a 6-week randomized double-blind placebo-controlled trial to ...
Video
February 2018Late-Onset ADHD Reconsidered With Comprehensive Repeated Assessments Between Ages 10 and 25
- Margaret H. Sibley,Ph.D.,
- Luis A. Rohde,M.D.,
- James M. Swanson,Ph.D.,
- Lily T. Hechtman,M.D.,
- Brooke S.G. Molina,Ph.D.,
- John T. Mitchell,Ph.D.,
- L. Eugene Arnold,M.D.,
- Arthur Caye,
- Traci M. Kennedy,Ph.D.,
- Arunima Roy,Ph.D.,
- Annamarie Stehli,M.P.H.,
- for the Multimodal Treatment Study of Children with ADHD (MTA) Cooperative Group
- Pages:140–149
- Published Online:20 October 2017
https://doi.org/10.1176/appi.ajp.2017.17030298
Preview Abstract
Objective:Adolescents and young adults without childhood attention deficit hyperactivity disorder (ADHD) often present to clinics seeking stimulant medication for late-onset ADHD symptoms. Recent birth-cohort studies support the notion of late-onset ADHD, ...
Audio
February 2018The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis
- Samuel T. Wilkinson,M.D.,
- Elizabeth D. Ballard,Ph.D.,
- Michael H. Bloch,M.D., M.S.,
- Sanjay J. Mathew,M.D.,
- James W. Murrough,M.D., Ph.D.,
- Adriana Feder,M.D.,
- Peter Sos,M.D., Ph.D.,
- Gang Wang,M.D.,
- Carlos A. Zarate, Jr.,M.D.,
- Gerard Sanacora,M.D., Ph.D.
- Pages:150–158
- Published Online:3 October 2017
https://doi.org/10.1176/appi.ajp.2017.17040472
Preview Abstract
Objective:Suicide is a public health crisis with limited treatment options. The authors conducted a systematic review and individual participant data meta-analysis examining the effects of a single dose of ketamine on suicidal ideation.Method:Individual ...
February 2018
Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer’s Disease: A Double-Blind, Randomized, Placebo-Controlled Trial
- Prasad R. Padala,M.D., M.S.,
- Kalpana P. Padala,M.D., M.S.,
- Shelly Y. Lensing,M.S.,
- Daniel Ramirez,M.S.,
- Varun Monga,M.D.,
- Melinda M. Bopp,B.S.,
- Paula K. Roberson,Ph.D.,
- Richard A. Dennis,Ph.D.,
- Frederick Petty,M.D., Ph.D.,
- Dennis H. Sullivan,M.D.,
- William J. Burke,M.D.
- Pages:159–168
- Published Online:15 September 2017
https://doi.org/10.1176/appi.ajp.2017.17030316
Preview Abstract
Objective:Apathy is a common behavioral problem in Alzheimer’s disease. Apathy has profound consequences, such as functional impairment, higher service utilization, higher caregiver burden, and increased mortality. The authors’ objective was to study the ...
February 2018
Psychopharmacological Treatment in the RAISE-ETP Study: Outcomes of a Manual and Computer Decision Support System Based Intervention
- Delbert G. Robinson,M.D.,
- Nina R. Schooler,Ph.D.,
- Christoph U. Correll,M.D.,
- Majnu John,Ph.D.,
- Benji T. Kurian,M.D., M.P.H.,
- Patricia Marcy,B.S.N.,
- Alexander L. Miller,M.D.,
- Ronny Pipes,M.A., L.P.C.-S.,
- Madhukar H. Trivedi,M.D.,
- John M. Kane,M.D.
- Pages:169–179
- Published Online:15 September 2017
https://doi.org/10.1176/appi.ajp.2017.16080919
Preview Abstract
Objective:The Recovery After an Initial Schizophrenia Episode–Early Treatment Program compared NAVIGATE, a comprehensive program for first-episode psychosis, to clinician-choice community care over 2 years. Quality of life and psychotic and depressive ...
Video
February 2018Cortical Functional Connectivity Evident After Birth and Behavioral Inhibition at Age 2
- Chad M. Sylvester,M.D., Ph.D.,
- Christopher D. Smyser,M.D.,
- Tara Smyser,M.S.,
- Jeanette Kenley,B.S.,
- Joseph J. Ackerman, Jr.,B.S.,
- Joshua S. Shimony,M.D., Ph.D.,
- Steve E. Petersen,Ph.D.,
- Cynthia E. Rogers,M.D.
- Pages:180–187
- Published Online:4 August 2017
https://doi.org/10.1176/appi.ajp.2017.17010018
Preview Abstract
Objective:The infant temperament behavioral inhibition is a potent risk factor for development of an anxiety disorder. It is difficult to predict risk for behavioral inhibition at birth, however, and the neural underpinnings are poorly understood. The ...
Letters to the Editor
February 2018
The Impact of Underpowered Studies on Clinical Trial Results
- Arif Khan,M.D.,
- Kaysee Fahl Mar,M.A.,
- Walter A. Brown,M.D.
- Page:188
- Published Online:1 February 2018
February 2018
The Importance of Adequately Powered Clinical Studies: Response to Khan et al.
- Stephen R. Marder,M.D.,
- Thomas Laughren,M.D.,
- Steven J. Romano,M.D.
- Pages:188–189
- Published Online:1 February 2018
February 2018
Pharmacogenetic Tests in Psychiatry
- Chad Bousman,M.P.H., Ph.D.,
- Josiah Allen,B.A.,
- Harris A. Eyre,M.D., Ph.D.
- Page:189
- Published Online:1 February 2018
Book Forum
February 2018
The Psychoses of Menstruation and Childbearing
- Jennifer L. Payne,M.D.
- Pages:190–191
- Published Online:1 February 2018
February 2018
Public Health Perspectives on Depressive Disorders
- Charles R. Conway,M.D.
- Pages:191–192
- Published Online:1 February 2018
