
Gabbard’s Treatments of Psychiatric Disorders, 5th Edition
Chapter 14 of this textbook reviews the pharmacological landscape and experimental horizon in Major Depressive Disorder (MDD).
Continue reading online inChapter 14: Pharmacological and Somatic Treatments for Major Depressive Disorder.

Help With Depression
Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Fortunately, it is also treatable.

The American Journal of Psychiatry
Specific challenges profoundly affect the outcome of treatment for depression. View the AJP articles below to find out more.
Improving Depression Outcome by Patient-Centered Medical Management -Read the article
A Cruel Irony for Clinicians Who Treat Depression -Read the article
What Is Depression?
Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act.
Fortunately, it is also treatable. Depression causes feelings of sadness and/or a loss of interest in activities once enjoyed. It can lead to a variety of emotional and physical problems and can decrease a person’s ability to function at work and at home.
American Journal of Psychiatry
Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study
Published online:08 Mar 2019Supporting Providers After Drug Overdose Death
Published online:01 Mar 2019
Biomarkers of Autoimmunity in Acute Psychiatric Disorders
Published online:19 Mar 2019An Investigation Into Response Inhibition in Distinct Clinical Groups Within Obsessive-Compulsive Disorder
Published online:19 Mar 2019
Psychiatric News
Co-Occurring Mental Illnesses May Be More Pervasive Than Previously Thought
Published online:15 Mar 2019Physical Activity May Lower, Prevent Depression
Published online:15 Mar 2019Journal Digest
Published online:15 Mar 2019
Patient Story: Depression
Trish was a 51-year-old woman who was brought to the emergency room by her husband. She said, “I feel like killing myself.” She had lost her interest in life about four months before. During that time, she reported depression every day for most of the day. Symptoms had been getting worse for months...continue reading
About This Story
This patient story is excerpted fromUnderstanding Mental Disorders: A Patient And Family Resource.Based on the latest, fifth edition of theDiagnostic and Statistical Manual of Mental Disorders—known as DSM-5®—Understanding Mental Disorders provides valuable insight on what to expect from an illness and its treatment—and will help readers recognize symptoms, know when to seek help, and get the right care. Featured disorders include depression, schizophrenia, ADHD, autism spectrum disorder, posttraumatic stress disorder, and bipolar disorder, among others.
American Journal of Psychotherapy
Why Is It Easier to Get Mad Than It Is to Feel Sad? Pilot Study of Regulation-Focused Psychotherapy for Children
Published online:21 Feb 2019Which Problem Are We Addressing Today? The Utility of a Multifaceted Formulation Approach to a Complex Case
Published online:21 Feb 2019
FOCUS
Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap
Published online:01 Jan 2019From Molecules to Mind: Mechanisms of Action of Electroconvulsive Therapy
Published online:01 Jan 2019
Psychiatric Services
The Rise of Early Psychosis Care in California: An Overview of Community and University-Based Services
Published online:20 Mar 2019Mental Health Treatment Delay: A Comparison Among Civilians and Veterans of Different Service Eras
Published online:07 Mar 2019
Featured & Noteworthy Books:
View information on the treatment of depression inChapter 46 of this textbook.
Learn about depression in adolescents in these chapters.
Resource Centers
View curated content from our journals, books, textbooks, and other APA resources:
Seasonal Affective Disorder
Learn about Seasonal Affective Disorder, including symptoms, risk factors and treatment options.
Expert Q & A: Depression
Find answers to your questions about depression written by leading psychiatrists.
Find a Psychiatrist
A psychiatrist specializes in the diagnosis, treatment, and prevention of mental illness and substance abuse disorders. Psychiatrists are uniquely qualified to understand the complex interrelation between mental and physical health since their training includes four years of medical school and at least three additional years in a psychiatric residency.














