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Psychiatry Online
Sections

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Editorials
Commentary
Education in Psychiatry
April 2015
A Clinical Perspective on the Relevance of Research Domain Criteria in Electronic Health Records
  • Pages:316–320
  • Published Online:31 March 2015

https://doi.org/10.1176/appi.ajp.2014.14091177

Preview Abstract
Objective:The limitations of the DSM nosology for capturing dimensionality and overlap in psychiatric syndromes, and its poor correspondence to underlying neurobiology, have been well established. The Research Domain Criteria (RDoC), a proposed ...
Images in Psychiatry
Reviews and Overviews
April 2015
Modifiable Predictors of Dementia in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis
  • Pages:323–334
  • Published Online:20 February 2015

https://doi.org/10.1176/appi.ajp.2014.14070878

Preview Abstract
Objective:Public health campaigns encouraging early help seeking have increased rates of mild cognitive impairment (MCI) diagnosis in Western countries, but we know little about how to treat or predict dementia outcomes in persons with the condition....
Articles
April 2015
Effects of Cognitive Bias Modification Training on Neural Alcohol Cue Reactivity in Alcohol Dependence
  • Pages:335–343
  • Published Online:19 December 2014

https://doi.org/10.1176/appi.ajp.2014.13111495

Preview Abstract
Objective:In alcohol-dependent patients, alcohol cues evoke increased activation in mesolimbic brain areas, such as the nucleus accumbens and the amygdala. Moreover, patients show an alcohol approach bias, a tendency to more quickly approach than avoid ...
April 2015
Pragmatic Replication Trial of Health Promotion Coaching for Obesity in Serious Mental Illness and Maintenance of Outcomes
  • Pages:344–352
  • Published Online:12 December 2014

https://doi.org/10.1176/appi.ajp.2014.14030357

Preview Abstract
Objective:Few studies targeting obesity in serious mental illness have reported clinically significant risk reduction, and none have been replicated in community settings or demonstrated sustained outcomes after intervention withdrawal. The authors sought ...
April 2015
Association ofCRP Genetic Variation and CRP Level With Elevated PTSD Symptoms and Physiological Responses in a Civilian Population With High Levels of Trauma
  • Pages:353–362
  • Published Online:12 December 2014

https://doi.org/10.1176/appi.ajp.2014.14020263

Preview Abstract
Objective:Increased systemic inflammation is associated with stress-related psychopathology. Specifically, levels of the proinflammatory marker C-reactive protein (CRP) are elevated in individuals with posttraumatic stress disorder (PTSD). Furthermore, ...
April 2015
Validation of Electronic Health Record Phenotyping of Bipolar Disorder Cases and Controls
  • Pages:363–372
  • Published Online:12 December 2014

https://doi.org/10.1176/appi.ajp.2014.14030423

Preview Abstract
Objective:The study was designed to validate use of electronic health records (EHRs) for diagnosing bipolar disorder and classifying control subjects.Method:EHR data were obtained from a health care system of more than 4.6 million patients spanning more ...
April 2015
Synaptic Proteins in the Hippocampus Indicative of Increased Neuronal Activity in CA3 in Schizophrenia
  • Pages:373–382
  • Published Online:13 January 2015

https://doi.org/10.1176/appi.ajp.2014.14010123

Preview Abstract
Objective:In schizophrenia, hippocampal perfusion is increased and declarative memory function is degraded. Based on an a priori model of hippocampal dysfunction in schizophrenic psychosis, the authors postulated molecular and cellular changes in CA3 ...
April 2015
Reward-Based Spatial Learning in Unmedicated Adults With Obsessive-Compulsive Disorder
  • Pages:383–392
  • Published Online:19 December 2014

https://doi.org/10.1176/appi.ajp.2014.13121700

Preview Abstract
Objective:The authors assessed the functioning of mesolimbic and striatal areas involved in reward-based spatial learning in unmedicated adults with obsessive-compulsive disorder (OCD).Method:Functional MRI blood-oxygen-level-dependent response was ...
Letters to the Editor
Disclosure of Editors’ Financial Relationships
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