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Psychiatry Online
Sections

The American Psychiatric Association (APA) has updated itsPrivacy Policy andTerms of Use, including with new information specifically addressed to individuals in the European Economic Area. As described in the Privacy Policy and Terms of Use, this website utilizes cookies, including for the purpose of offering an optimal online experience and services tailored to your preferences.

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cover

American Journal of Psychiatry

Volume 159, Issue 4

April 2002
Editorial
Reviews and Overviews
April 2002
The Illness of Vincent van Gogh
  • Pages:519–526
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.519

Preview Abstract
Vincent van Gogh (1853–1890) had an eccentric personality and unstable moods, suffered from recurrent psychotic episodes during the last 2 years of his extraordinary life, and committed suicide at the age of 37. Despite limited evidence, well over 150 ...
Images in Neuroscience
Clinical Case Conference
Images in Psychiatry
Article
April 2002
A Twin Study of Genetic Relationships Between Psychotic Symptoms
  • Pages:539–545
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.539

Preview Abstract
OBJECTIVE: Biometrical model fitting was applied to clinical data from twins to investigate whether operationally defined schizophrenic, schizoaffective, and manic syndromes share genetic risk factors. METHOD: Seventy-seven monozygotic and 89 same-sex ...
April 2002
Impaired Cortical Network for Preattentive Detection of Change in Speech Sounds in Schizophrenia: A High-Resolution Event-Related Potential Study
  • Pages:546–553
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.546

Preview Abstract
OBJECTIVE: Schizophrenia is associated with language-related dysfunction. At the most basic level, the dysfunction of schizophrenic patients in perceiving phoneme boundaries has been demonstrated in a behavioral task. The goal in this study was to obtain ...
April 2002
A Multidose Study of Haloperidol Decanoate in the Maintenance Treatment of Schizophrenia
  • Pages:554–560
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.554

Preview Abstract
OBJECTIVE: Maintenance medication is critical in the prevention of psychotic relapse and rehospitalization among patients with schizophrenia. Given potential adverse effects, identification of the minimum effective dose is clinically important. METHOD: A ...
April 2002
Association of Diabetes Mellitus With Use of Atypical Neuroleptics in the Treatment of Schizophrenia
  • Pages:561–566
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.561

Preview Abstract
OBJECTIVE: The development of both type I and type II diabetes after initiation of some atypical neuroleptics has been reported, primarily in studies involving small series of patients. This study used administrative data from a large national sample of ...
April 2002
Racial Disparities in Antipsychotic Prescription Patterns for Patients With Schizophrenia
  • Pages:567–572
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.567

Preview Abstract
OBJECTIVE: This study aimed to examine the extent and type of variation in antipsychotic prescription patterns between African American and Caucasian patients with schizophrenia. METHOD: Subjects were 2,515 adult Medicaid recipients treated for ...
April 2002
Patient and Psychiatrist Ratings of Hypothetical Schizophrenia Research Protocols: Assessment of Harm Potential and Factors Influencing Participation Decisions
  • Pages:573–584
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.573

Preview Abstract
OBJECTIVE: A central ethical issue in schizophrenia research is whether participants are able to provide informed consent, particularly for protocols entailing medication washouts or placebo treatments. Few data show how patients with schizophrenia and ...
April 2002
Views of Potential Subjects Toward Proposed Regulations for Clinical Research With Adults Unable to Consent
  • Pages:585–591
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.585

Preview Abstract
OBJECTIVE: The authors’ goal was to assess healthy individuals’ attitudes toward five of the most prominent proposed safeguards regarding the consent process for research with adults unable to consent. METHOD: Telephone interviews were conducted with 246 ...
April 2002
Obsessive-Compulsive and Panic Symptoms in Patients With First-Admission Psychosis
  • Pages:592–598
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.592

Preview Abstract
OBJECTIVE: The occurrence, persistence and specificity of the association between comorbid obsessive-compulsive and panic symptoms and three psychotic disorders—schizophrenia/schizoaffective disorder, bipolar disorder with psychosis, and major depression ...
April 2002
Serotonin Transporter Distribution and Density in the Cerebral Cortex of Alcoholic and Nonalcoholic Comparison Subjects: A Whole-Hemisphere Autoradiography Study
  • Pages:599–606
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.599

Preview Abstract
OBJECTIVE: Lesions of the medial prefrontal cortex and dysfunctions in serotonin turnover are two well-established factors associated with impulsive and sociopathic behaviors, but no firm neuroanatomical data have linked these pathophysiological findings. ...
April 2002
Family Functioning and Peer Affiliation in Children of Fathers With Antisocial Personality Disorder and Substance Dependence: Associations With Problem Behaviors
  • Pages:607–614
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.607

Preview Abstract
OBJECTIVE: Family functioning and peer influences are theoretically linked to child psychopathology. This study quantified the functional status of families with fathers with substance dependence with or without comorbid antisocial personality disorder ...
April 2002
Age, Gender, and Ethnicity Differences in Patterns of Cocaine and Ethanol Use Preceding Suicide
  • Pages:615–619
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.615

Preview Abstract
OBJECTIVE: The goal of this study was to examine the relationship between suicide and substance use among completed suicides in Fulton County, Ga., from 1994 through 1998. METHOD: Extensive data on completed suicides were obtained from records of the ...
April 2002
Risk Factors for 12-Month Comorbidity of Mood, Anxiety, and Substance Use Disorders: Findings From the Netherlands Mental Health Survey and Incidence Study
  • Pages:620–629
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.620

Preview Abstract
OBJECTIVE: This study examined risk factor profiles of pure and comorbid 12-month mood, anxiety, and substance use disorder in the general population. METHOD: Data were derived from the Netherlands Mental Health Survey and Incidence Study, a prospective ...
April 2002
Frontal White Matter Biochemical Abnormalities in Late-Life Major Depression Detected With Proton Magnetic Resonance Spectroscopy
  • Pages:630–636
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.630

Preview Abstract
OBJECTIVE: Neuroanatomical abnormalities have been identified in patients with late-life mood disorders by using magnetic resonance imaging. This study examined the biochemical correlates of late-life major depression in the frontal gray and white matter ...
April 2002
A Descriptive Analysis of Minor Depression
  • Pages:637–643
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.637

Preview Abstract
OBJECTIVE: The authors provide a detailed clinical description of minor depression: its symptoms, level of disability, stability, and relationship to patient and family history of major depressive disorder. METHOD: Rigorous criteria for minor depression, ...
April 2002
Negative Symptoms in Temporal Lobe Epilepsy
  • Pages:644–651
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.644

Preview Abstract
OBJECTIVE: This study examined the frequency of negative and positive symptoms in nonpsychotic patients with temporal lobe epilepsy and the relationship of negative and positive symptoms to cognition, quantitative magnetic resonance imaging (MRI) ...
Brief Report
April 2002
A Functional Polymorphism in the COMT Gene and Performance on a Test of Prefrontal Cognition
  • Pages:652–654
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.652

Preview Abstract
OBJECTIVE: In the prefrontal cortex, the enzyme catecholO-methyltransferase (COMT) is critical in the metabolic degradation of dopamine, a neurotransmitter hypothesized to influence human cognitive function. The COMT gene contains a functional ...
April 2002
Metformin for Weight Loss in Pediatric Patients Taking Psychotropic Drugs
  • Pages:655–657
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.655

Preview Abstract
OBJECTIVE: Metformin was assessed as a treatment for weight gain in children taking olanzapine, risperidone, quetiapine, or valproate. METHOD: The subjects were 19 patients aged 10–18 years; 15 were white and four were black, and there were 12 boys and ...
April 2002
An Animal Model of Tourette’s Syndrome
  • Pages:657–660
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.657

Preview Abstract
OBJECTIVE: An animal model was used to investigate an autoimmune etiology for some cases of Tourette’s syndrome. METHOD: Sera from 12 patients with Tourette’s syndrome with high levels of antineural or antinuclear antibodies were infused bilaterally into ...
April 2002
Comparative Study of Trauma-Related Phenomena in Subjects With Pseudoseizures and Subjects With Epilepsy
  • Pages:660–663
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.660

Preview Abstract
OBJECTIVE: The purpose of this study was to examine potential differences in measures of trauma-related phenomena between subjects with pseudoseizures and subjects with intractable epilepsy. METHOD: Thirty-one adult subjects with pseudoseizures and 32 ...
April 2002
Increased Occipital Cortex GABA Concentrations in Depressed Patients After Therapy With Selective Serotonin Reuptake Inhibitors
  • Pages:663–665
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.663

Preview Abstract
OBJECTIVE: Studies have demonstrated low concentrations of γ-aminobutyric acid (GABA) in the plasma and CSF of individuals with major depression, and low GABA concentrations have also been found in the occipital cortex of depressed subjects. The goal of ...
April 2002
An Open Trial of Morning Light Therapy for Treatment of Antepartum Depression
  • Pages:666–669
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.666

Preview Abstract
OBJECTIVE: About 5% of pregnant women meet criteria for major depression. No pharmacotherapy is specifically approved for antepartum depression; novel treatment approaches may be welcome. The authors explored the use of morning bright light therapy for ...
April 2002
Ødegaard’s Selection Hypothesis Revisited: Schizophrenia in Surinamese Immigrants to the Netherlands
  • Pages:669–671
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.669

Preview Abstract
OBJECTIVE: The incidence of schizophrenia among Surinamese immigrants to the Netherlands is high. The authors tested Ødegaard’s hypothesis that this phenomenon is explained by selective migration. METHOD: The authors imagined that migration from Surinam ...
Letter to the Editor
April 2002
Serotonin Syndrome and Atypical Antipsychotics
  • Pages:672-a–673
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.672-a

April 2002
Ziprasidone Induction of Hypomania in Depression?
  • Pages:673–674
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.673

April 2002
Quetiapine and Pregnancy
  • Page:674
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.674

April 2002
Creativity and Affective Illness
  • Pages:675-a–676
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.675-a

April 2002
Creativity and Affective Illness
  • Pages:676–677
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.676

April 2002
Creativity and Affective Illness
  • Page:677
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.677

April 2002
Dr. McDermott Replies
  • Pages:677-a–677
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.677-a

April 2002
Buproprion and Sexual Dysfunction
  • Pages:677-b–677
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.677-b

April 2002
Dr. Ashton and Colleagues Reply
  • Pages:677-c–678
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.677-c

April 2002
Early-Stage Vision and Schizophrenia
  • Page:678
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.678

April 2002
Neuropsychiatric Testing and the Menstrual Cycle
  • Pages:679–680
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.679

April 2002
Suicide Risk in Placebo-Controlled Studies
  • Pages:680-a–681
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.680-a

April 2002
Dr. Storosum and Colleagues Reply
  • Page:681
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.681

April 2002
Panic and Depression
  • Pages:681-a–681
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.681-a

April 2002
Drs. Goodwin and Olfson Reply
  • Pages:681-b–682
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.681-b

April 2002
Take the Time to Listen
  • Page:682
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.682

Book Forum: The Schizophrenia Spectrum
April 2002
Schizophrenia in Children and Adolescents
  • Page:685
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.685

Book Forum: Posttraumatic Stress
Book Forum: Anger/Hostility/Violence
April 2002
Base Instincts: What Makes Killers Kill
  • Pages:689-a–690
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.689-a

Book Forum: Sexuality
April 2002
Self-Injurious Behaviors: Assessment and Treatment
  • Page:692
  • Published Online:1 April 2002

https://doi.org/10.1176/appi.ajp.159.4.692

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