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The Wayback Machine - https://web.archive.org/web/20051130210724/http://www.jco.org:80/content/vol23/issue11/
http://www.aacr.org/page4484.aspx 
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MOLECULAR ONCOLOGY: Receptor-Based Therapy

Other Issues:
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OVERVIEW
ORIGINAL REPORTS
 Predictive Biomarkers/Translational Research
 Clinical Trials
REVIEW ARTICLE
ART OF ONCOLOGY
SPECIAL DEPARTMENTS
 Correspondence
GLOSSARY

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To see an article, click its [Full Text] or [PDF] link.To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button.To see one abstract at a time, click its [Abstract] link.

 
Critical Update and Emerging Trends in Epidermal Growth Factor Receptor Targeting in Cancer
José Baselga and Carlos L. Arteaga
JCO Apr 10 2005: 2445–2459. .[Abstract][Full Text][PDF] 

 

 

Neoadjuvant Trastuzumab Induces Apoptosis in Primary Breast Cancers
Syed K. Mohsin, Heidi L. Weiss, M. Carolina Gutierrez, Gary C. Chamness, Rachel Schiff, Michael P. DiGiovanna, Chun-Xia Wang, Susan G. Hilsenbeck, C. Kent Osborne, D. Craig Allred, Richard Elledge, and Jenny C. Chang
JCO Apr 10 2005: 2460–2468. .[Abstract][Full Text][PDF] 

Molecular Changes in Tamoxifen-Resistant Breast Cancer: Relationship Between Estrogen Receptor, HER-2, and p38 Mitogen-Activated Protein Kinase
M. Carolina Gutierrez, Simone Detre, Stephen Johnston, Syed K. Mohsin, Jiang Shou, D. Craig Allred, Rachel Schiff, C. Kent Osborne, and Mitch Dowsett
JCO Apr 10 2005: 2469–2476. .[Abstract][Full Text][PDF] 

Biomarker Changes During Neoadjuvant Anastrozole, Tamoxifen, or the Combination: Influence of Hormonal Status and HER-2 in Breast Cancer—A Study from the IMPACT Trialists
Mitch Dowsett, Steve R. Ebbs, J. Michael Dixon, Anthony Skene, Clive Griffith, Irene Boeddinghaus, Janine Salter, Simone Detre, Margaret Hills, Susan Ashley, Stephen Francis, Geraldine Walsh, and Ian E. Smith
JCO Apr 10 2005: 2477–2492. .[Abstract][Full Text][PDF] 

Predictive and Prognostic Impact of Epidermal Growth Factor Receptor Mutation in Non–Small-Cell Lung Cancer Patients Treated With Gefitinib
Sae-Won Han, Tae-You Kim, Pil Gyu Hwang, Soohyun Jeong, Jeongmi Kim, In Sil Choi, Do-Youn Oh, Jee Hyun Kim, Dong-Wan Kim, Doo Hyun Chung, Seock-Ah Im, Young Tae Kim, Jong Seok Lee, Dae Seog Heo, Yung-Jue Bang, and Noe Kyeong Kim
JCO Apr 10 2005: 2493–2501. .[Abstract][Full Text][PDF] 

Study of the Biologic Effects of Lapatinib, a Reversible Inhibitor of ErbB1 and ErbB2 Tyrosine Kinases, on Tumor Growth and Survival Pathways in Patients With Advanced Malignancies
Neil L. Spector, Wenle Xia, Howard Burris, III, Herbert Hurwitz, E. Claire Dees, Afshin Dowlati, Bert O'Neil, Beth Overmoyer, Paul K. Marcom, Kimberly L. Blackwell, Deborah A. Smith, Kevin M. Koch, Andrew Stead, Steven Mangum, Matthew J. Ellis, Leihua Liu, Albert K. Man, Troy M. Bremer, Jennifer Harris, and Sarah Bacus
JCO Apr 10 2005: 2502–2512. .[Abstract][Full Text][PDF] 

Mutations of the Epidermal Growth Factor Receptor Gene Predict Prolonged Survival After Gefitinib Treatment in Patients With Non–Small-Cell Lung Cancer With Postoperative Recurrence
Tetsuya Mitsudomi, Takayuki Kosaka, Hideki Endoh, Yoshitsugu Horio, Toyoaki Hida, Shoichi Mori, Shunzo Hatooka, Masayuki Shinoda, Takashi Takahashi, and Yasushi Yatabe
JCO Apr 10 2005: 2513–2520. .[Abstract][Full Text][PDF] 

 

Phase I Pharmacokinetic and Pharmacodynamic Study of Weekly 1-Hour and 24-Hour Infusion BMS-214662, a Farnesyltransferase Inhibitor, in Patients With Advanced Solid Tumors
Josep Tabernero, Fredy Rojo, Irene Marimón, Maurizio Voi, Joan Albanell, Marta Guix, Federico Vázquez, Joan Carulla, Michael Cooper, Jordi Andreu, Anne Van Vreckem, Joaquim Bellmunt, Veeraswamy Manne, James A. Manning, Carmen Garrido, Enriqueta Felip, Josep Maria del Campo, Mónica García, Sonia Valverde, and José Baselga
JCO Apr 10 2005: 2521–2533. .[Abstract][Full Text][PDF] 

Phase I Clinical Study of Pertuzumab, a Novel HER Dimerization Inhibitor, in Patients With Advanced Cancer
David B. Agus, Michael S. Gordon, Charles Taylor, Ronald B. Natale, Beth Karlan, David S. Mendelson, Michael F. Press, David E. Allison, Mark X. Sliwkowski, Gracie Lieberman, Stephen M. Kelsey, and Gwen Fyfe
JCO Apr 10 2005: 2534–2543. .[Abstract][Full Text][PDF] 

Phase I/II Trial Evaluating the Anti-Vascular Endothelial Growth Factor Monoclonal Antibody Bevacizumab in Combination With the HER-1/Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Erlotinib for Patients With Recurrent Non–Small-Cell Lung Cancer
Roy S. Herbst, David H. Johnson, Eric Mininberg, David P. Carbone, Ted Henderson, Edward S. Kim, George Blumenschein, Jr, Jack J. Lee, Diane D. Liu, Mylene T. Truong, Waun K. Hong, Hai Tran, Anne Tsao, Dong Xie, David A. Ramies, Robert Mass, Somasekar Seshagiri, David A. Eberhard, Sean K. Kelley, and Alan Sandler
JCO Apr 10 2005: 2544–2555. .[Abstract][Full Text][PDF] 

 
Epidermal Growth Factor Receptor Mutations, Small-Molecule Kinase Inhibitors, and Non–Small-Cell Lung Cancer: Current Knowledge and Future Directions
William Pao and Vincent A. Miller
JCO Apr 10 2005: 2556–2568. .[Abstract][Full Text][PDF] 

 
Inter-Religious Perspectives on Hope and Limits in Cancer Treatment
Alan B. Astrow, Ingrid Mattson, Rabbi James Ponet, and Michelle White
JCO Apr 10 2005: 2569–2573.[Full Text][PDF] 

 

 

Thromboembolic Events in Gastric Cancer: High Incidence in Patients Receiving Irinotecan- and Bevacizumab-Based Therapy
Manish A. Shah, David Ilson, and David P. Kelsen
JCO Apr 10 2005: 2574–2576. .[Full Text][PDF] 

 
Glossary

JCO Apr 10 2005: 2577–2582.[PDF] 



To see an article, click its [Full Text] or [PDF] link.To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button.To see one abstract at a time, click its [Abstract] link.


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