| Năm | Tên | Vai diễn | Notes |
|---|
| 1954 | The Beachcomber | Tromp | |
| 1954 | Orders Are Orders | Corporal Martin | Credited as Donald Plesance |
| 1955 | Value for Money | Limpy | |
| 1956 | 1984 | R. Parsons | |
| 1956 | The Black Tent | Ali | |
| 1956 | The Adventures of Robin Hood | Prince John | TV series (4 episodes) |
| 1957 | The Man in the Sky | Crabtree | (titledDecision Against Time in the U.S.) |
| 1957 | Manuela | Evans | |
| 1957 | Barnacle Bill | Cashier | (titledAll at Sea in the U.S.) |
| 1958 | A Tale of Two Cities | John Barsad | |
| 1958 | Heart of a Child | Spiel | |
| 1958 | The Wind Cannot Read | Doctor | |
| 1958 | The Man Inside | Organ-grinder | |
| 1958 | The Two-Headed Spy | General Hardt | |
| 1959 | The Scarf | Detective Inspector Harry Yates | TV series (6 episodes) |
| 1959 | Look Back in Anger | Hurst | |
| 1959 | Killers of Kilimanjaro | Captain | |
| 1959 | The Battle of the Sexes | Irwin Hoffman | |
| 1960 | The Shakedown | Jessel Brown | |
| 1960 | The Flesh and the Fiends | William Hare | |
| 1960 | Sons and Lovers | Pappleworth | |
| 1960 | Hell Is a City | Gus Hawkins | |
| 1960 | Circus of Horrors | Vanet | |
| 1960 | The Hands of Orlac | Graham Coates | |
| 1961 | What a Carve Up! | Everett Sloane | |
| 1961 | No Love for Johnnie | Roger Renfrew | |
| 1961 | A Story of David | Nabal | |
| 1961 | Spare the Rod | Mr. Jenkins | |
| 1962 | The Inspector | Sergeant Wolters | |
| 1962 | Dr. Crippen | Dr Crippen | |
| 1963 | The Great Escape | RAF Colin Blythe, "The Forger" | |
| 1963 | The Outer Limits | Prof. Harold Finley | TV series (episode: "The Man With the Power") |
| 1965 | The Hallelujah Trail | Oracle Jones | |
| 1965 | The Greatest Story Ever Told | Satan | |
| 1966 | Fantastic Voyage | Dr. Michaels | |
| 1966 | Cul-de-sac | George | |
| 1966 | Eye of the Devil | Pere Dominic | |
| 1967 | You Only Live Twice | Ernst Stavro Blofeld | |
| 1967 | The Night of the Generals | General Kahlenberge | |
| 1967 | Matchless | Gregori Andreanu | |
| 1968 | The Other People | Clive | |
| 1968 | Will Penny | Preacher Quint | |
| 1969 | Arthur? Arthur! | Arthur Brownjohn | |
| 1969 | The Madwoman of Chaillot | The Prospector | |
| 1970 | Soldier Blue | Isaac Q. Cumber | |
| 1971 | THX 1138 | SEN 5241 | |
| 1971 | Wake in Fright | Doc Tydon | |
| 1971 | Kidnapped | Ebenezer Balfour | |
| 1972 | The Pied Piper | The Baron | |
| 1972 | Death Line | Inspector Calhoun | |
| 1972 | Innocent Bystanders | Loomis | |
| 1972 | Henry VIII and His Six Wives | Thomas Cromwell | |
| 1972 | The Jerusalem File | Major Samuels | |
| 1972 | Wedding in White | Jim Dougall | |
| 1973 | Tales That Witness Madness | Professor Tremayne | |
| 1973 | Malachi's Cove | Malachi | |
| 1973 | Columbo | Adrian Carsini | |
| 1974 | Watch Out, We're Mad | The Doctor | |
| 1974 | From Beyond the Grave | Jim Underwood | Segment: "An Act of Kindness" |
| 1974 | House of the Damned | Martin Zayas | Original title:La loba y la Paloma |
| 1974 | The Mutations | Professor Nolter | |
| 1974 | The Black Windmill | Cedric Harper | |
| 1974 | Barry Mckenzie Holds His Own | Count Plasma | |
| 1975 | Escape to Witch Mountain | Lucas Deranian | |
| 1975 | The Count of Monte Cristo | Baron Danglars | |
| 1975 | I Don't Want to Be Born | Dr. Finch | |
| 1975 | Journey into Fear | Kuvelti | |
| 1975 | Hearts of the West | A.J. Neitz | Alternate title:Hollywood Cowboy |
| 1976 | Land of the Minotaur | Father Roche | Alternate title:The Devil's Men |
| 1976 | The Eagle Has Landed | Himmler | |
| 1976 | Trial by Combat | Sir Giles Marley | Alternate title:Dirty Knights' Work |
| 1976 | The Last Tycoon | Boxley | |
| 1976 | The Passover Plot | Pontius Pilate | |
| 1977 | The Uncanny | Valentine De'ath | Segment: "Hollywood 1936" |
| 1977 | Oh, God! | Dr. Harmon | |
| 1977 | Telefon | Nikolai Dalchimsky | |
| 1977 | Jesus of Nazareth | Melchior | TV miniseries |
| 1978 | Halloween | Dr. Loomis | |
| 1978 | Blood Relatives | James Doniac | |
| 1978 | Night Creature | Axel MacGregor | Alternate title:Out of the Darkness |
| 1978 | The Bastard | Solomon Sholto | TV miniseries |
| 1978 | Tomorrow Never Comes | Dr. Todd | |
| 1978 | Sgt. Pepper's Lonely Hearts Club Band | B.D. Hoffler/B.D. Brockhurst | |
| 1978 | Power Play | Blair | |
| 1978 | Centennial | Sam Purchas | TV miniseries |
| 1978 | L'Ordre et la sécurité du monde | Rothko | Alternate title:Last In, First Out |
| 1979 | Good Luck, Miss Wyckoff | Dr. Steiner | |
| 1979 | Dracula | Dr. Jack Seward | |
| 1979 | All Quiet on the Western Front | Kantorek | TV film |
| 1979 | Jaguar Lives! | General Villanova | |
| 1979 | The French Atlantic Affair | Max Dechambre | TV miniseries |
| 1980 | The Pumaman | Dr. Kobras | |
| 1980 | The Monster Club | Pickering | |
| 1980 | Halloween: Extended Edition | Dr. Loomis | Appeared in additional footage (filmed during the production ofHalloween II) not included in the original film but featured in the NBC television broadcast. |
| 1981 | Halloween II | Dr. Loomis | |
| 1981 | Race for the Yankee Zephyr | Gilbert "Gibbie" Carson | |
| 1981 | Escape from New York | Mr. President | |
| 1981 | Saturday Night Live | Himself-Guest host | 10/31/81 Halloween show with musical guest punk rock bandFear.John Belushi makes a guest appearance in the opening sketch. This would be Belushi's last SNL appearance. |
| 1982 | Alone in the Dark | Dr. Leo Bain | |
| 1982 | The Barchester Chronicles | Reverend Septimus Harding | TV series |
| 1983 | Warrior of the Lost World | Prossor | |
| 1983 | The Devonsville Terror | Dr. Warley | |
| 1983 | Where Is Parsifal? | Mackintosh | |
| 1984 | A Breed Apart | J.P. Whittier | |
| 1984 | The Ambassador | Eretz | |
| 1984 | Frankenstein's Great Aunt Tillie | Baron Victor Frankenstein | |
| 1985 | Black Arrow | Oliver Oates | TV film |
| 1985 | Arch of Triumph | Haake | |
| 1985 | Treasure of the Amazon | Klaus von Blantz | |
| 1985 | Phenomena | John McGregor | |
| 1985 | Nothing Underneath | Inspector Danesi | |
| 1986 | Cobra Mission | Father Lenoir | Alternate title:Operation Nam |
| 1987 | Django 2 | Gunn | |
| 1987 | Specters | Professor Lasky | |
| 1987 | Prince of Darkness | Priest | |
| 1987 | Ground Zero | Prosper Gaffney | |
| 1988 | The Great Escape II: The Untold Story | Dr. Absalon | TV film |
| 1988 | Hanna's War | Captain Thomas Rosza | |
| 1988 | Phantom of Death | Inspector Datti | |
| 1988 | Halloween 4: The Return of Michael Myers | Dr. Loomis | |
| 1988 | Vampire in Venice | Don Alvise | |
| 1988 | de [Der Commander] | Henry Carlson | |
| 1989 | Halloween 5: The Revenge of Michael Myers | Dr. Loomis | |
| 1989 | Ten Little Indians | Judge Lawrence Wargrave | |
| 1989 | fr [River of Death (film);River of Death] | Heinrich Spaatz | |
| 1989 | Casablanca Express | Colonel Bats | |
| 1990 | Buried Alive | Dr. Schaeffer | |
| 1991 | Shadows and Fog | Doctor | |
| 1992 | Dien Bien Phu | Howard Simpson | |
| 1993 | The Thief and the Cobbler | Phido the Vulture (voice) | |
| 1993 | The Big Freeze | Soup slurper | |
| 1993 | The Hour of the Pig | Pincheon | |
| 1995 | Halloween: The Curse of Michael Myers | Dr. Loomis | The film was dedicated to his memory. |
| 1996 | Fatal Frames | Prof. Robertson | |
