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Authors:Jinmo Jeong;Donghyeon Kim;Sangdo Jeong;Euiheon Chung;Sung Chan Jun;Jonghyun Lee andSohee Kim

Affiliation:Gwangju Institute of Science and Technology, Korea, Republic of

Keyword(s):Cortical Stimulation, Numerical Simulation, Finite Element Method, Brain Phantom.

RelatedOntology Subjects/Areas/Topics:Agents ;Artificial Intelligence ;Bioinformatics ;Biomedical Engineering ;Enterprise Information Systems ;Information Systems Analysis and Specification ;Methodologies and Technologies ;Model Design and Evaluation ;Operational Research ;Simulation

Abstract:The purpose of this study is to investigate the accuracy of numerical simulation for electric brain stimulation. For this, we modelled brains using simple computational models with 2 and 3 shells, with and without realistic head geometry, and performed numerical simulations using finite element method (FEM). The corresponding head phantoms were constructed for the validation of simulation results. We implanted stimulation electrodes in the head phantom, and measured the electric potential induced by the electrodes. When comparing the electric potential obtained from numerical simulations and phantom experiments, both results showed similar trend and amplitude, with a relative difference of 13.64% on average in the realistic head model study. This result demonstrates that predicting the electric potential and its gradient (current density) using computational simulation is reliable with reasonably small deviation from the actual measurement.

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Paper citation in several formats:
Jeong, J., Kim, D., Jeong, S., Chung, E., Jun, S. C., Lee, J. and Kim, S. (2014).Validation of Numerical Simulation for Subdural Cortical Stimulation - Using Spherical Phantoms and Anatomically Realistic Head Phantom. InProceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2014) - BIOINFORMATICS; ISBN 978-989-758-012-3; ISSN 2184-4305, SciTePress, pages 136-141. DOI: 10.5220/0004796801360141

@conference{bioinformatics14,
author={Jinmo Jeong and Donghyeon Kim and Sangdo Jeong and Euiheon Chung and Sung Chan Jun and Jonghyun Lee and Sohee Kim},
title={Validation of Numerical Simulation for Subdural Cortical Stimulation - Using Spherical Phantoms and Anatomically Realistic Head Phantom},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2014) - BIOINFORMATICS},
year={2014},
pages={136-141},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004796801360141},
isbn={978-989-758-012-3},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2014) - BIOINFORMATICS
TI - Validation of Numerical Simulation for Subdural Cortical Stimulation - Using Spherical Phantoms and Anatomically Realistic Head Phantom
SN - 978-989-758-012-3
IS - 2184-4305
AU - Jeong, J.
AU - Kim, D.
AU - Jeong, S.
AU - Chung, E.
AU - Jun, S.
AU - Lee, J.
AU - Kim, S.
PY - 2014
SP - 136
EP - 141
DO - 10.5220/0004796801360141
PB - SciTePress

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