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T-Coffee Server

  • Align Protein
    sequences

    Structural alignments (Expresso)

    Combine popular aligners (M-Coffee)

    Transmembrane proteins (PSI/TM-Coffee)

    Homology extension (PSI-Coffee)

  • Align RNA
    sequences

    Secondary structure (R-Coffee)

    Tertiary structure (SARA-Coffee)

    Combine popular aligners (M-Coffee)

  • Align DNA
    sequences

    Combine popular aligners (M-Coffee)

    Homologous promoter regions (Pro-coffee)

Evaluation

TCSEvaluates your Alignment and outputs a Colored version indicating the local reliability.  >>  Cite
iRMSD-APDBEvaluates Multiple Sequence Alignment using structural information with APDB and iRMSD.  >>  Cite
T-RMSDAllows fine-grained structural clustering of a given group of related protein domains  >>  Cite
StrikeEvaluation of protein MSAs using a single 3D structure  >>  Cite

Other

Advanced Run your alignment using full featured T-Coffee options.  >>  Cite
All All available T-Coffee methods

Useful links

Google GroupSupport and discussion group
tcoffee.orgFind out more about T-Coffee project and documentation
Cedric NotredameHome page,Courses andBlog
DownloadSources and binaries are available for download at this link
Twitter Check it out for latest T-Coffee developments and new tips
Facebook T-Coffee has a page on Facebook
ResearchGate Follow the discussion on ResearchGate

Mirror sites

Bioinfo for dummies
The BookBioinformatics For Dummies contains a T-Coffee tutorial and many otheronline resources.
Vital-ITVital-IT, Swiss Institute of Bioinformatics (SIB)
EBIEBI, European Bioinformatics Institute
IGS CNRS IGS lab., CNRS
Max-Planck InstituteMax-Planck Institute for Developmental Biology
CornellCornell
EMBNet-SpainEMBNet-Spain
Pasteur InstitutePasteur Institute

CRG logo T-Coffee Server is hosted by theCentre for Genomic Regulation (CRG) of Barcelona  - Powered byNextflow logo

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