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P49815 (TSC2_HUMAN)Homo sapiens (Human)

Tuberin UniProtKBInterProSTRINGInteractive Modelling

1807 aa;Sequence (Fasta); (Isoform 2;Isoform 3;Isoform 4;Isoform 5;Isoform 6;Isoform 7;Isoform 8)
Rendering slow - skipping non-selected models

Available Structures

2 Experimental Structures

DescriptionPDB IDOligo-stateRangeSeq id (%)Ligands
Structure of the TSC:WIPI3 lysosomal recruitment complex Heteromer
Q5MNZ6;Q92574;Q9P0N9;		35-1762
100.0
Cryo-EM structure of human TSC complex Heteromer
Q92574;Q9P0N9;		124-1755
100.0

3 SWISS-MODEL models

TemplateOligo-stateQMEANDisCoRangeLigandsTrg-Tpl Seq id (%)
9ce3.1.Amonomer0.7335-1762
99.78
5h2x.1.Amonomer0.5342-348
8.39
7ycx.1.Kmonomer0.5141-535
12.53

Model IDOligo-stateAvg pLDDTRangeTrg-Mdl Seq Id (%)

Model IDOligo-stateAvg ConfidenceRangeTrg-Mdl Seq id (%)

18 SWISS-MODEL models built on isoform sequence

IsoformTemplateOligo-stateQMEANDisCoRangeLigandsTrg-Tpl Seq id (%)
Isoform 29ce3.1.Amonomer0.7435-1719
99.31
Isoform 27lfc.1.Amonomer0.5142-346
11.15
Isoform 28rbz.1.Qmonomer0.5041-535
12.99
Isoform 39ce3.1.Amonomer0.7435-1718
99.37
Isoform 37lfc.1.Amonomer0.5242-346
11.15
Isoform 37ycx.1.Kmonomer0.5141-535
12.53
Isoform 49ce3.1.Amonomer0.7235-1739
100.00
Isoform 45h2x.1.Amonomer0.5342-348
8.39
Isoform 48rbz.1.Qmonomer0.5041-535
12.99
Isoform 59ce3.1.Amonomer0.7435-1695
99.60
Isoform 57lfc.1.Amonomer0.5141-346
11.11
Isoform 57k36.1.Amonomer0.5041-535
12.53
Isoform 69ce3.1.Amonomer0.7135-1659
99.59
Isoform 68sgh.1.Amonomer0.52198-481
12.13
Isoform 79ce3.1.Amonomer0.751-1647
99.59
Isoform 76wx8.1.Amonomer0.526-297
10.56
Isoform 78rc4.1.Amonomer0.515-486
12.20
Isoform 89ce3.1.Amonomer0.7435-115
97.32

Alignments

SWISS-MODEL based on, SMTL Version; Trg-Tpl Seq Id.

Average Model Confidence (QMEANDisCo):;Local Confidence
Average Model Confidence () :-;Local Confidence
:."". Released.

We predict this structure to be a membrane protein.

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