Movatterモバイル変換

[0]ホーム
URL:

P05067 (A4_HUMAN)Homo sapiens (Human)

Amyloid-beta precursor protein UniProtKBInterProSTRINGInteractive Modelling

770 aa;Sequence (Fasta); (Isoform 2;Isoform 3;Isoform 4;Isoform 5;Isoform 6;Isoform 7;Isoform 8;Isoform 9;Isoform 10;Isoform 11); 1 identical sequence:Homo sapiens:A0A140VJC8
Rendering slow - skipping non-selected models

It is possible new templates exist for this target since these models were created.

Available Structures

225 Experimental Structures

DescriptionPDB IDOligo-stateRangeSeq id (%)Ligands
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Kunitz Protease … Heteromer
P03951;		289-345
98.25
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN Heteromer
P00763;		287-342
100
Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human… Heteromer
Q92876;		289-343
100
Combinatorial Engineering of Proteolytically Resistant APPI Variants that Selectively Inhibit Human… Heteromer
Q92876;		289-343
100
BOVINE TRYPSIN COMPLEXED TO APPI Heteromer
P00760;		289-342
1002×CA;
BOVINE CHYMOTRYPSIN COMPLEXED TO APPI Heteromer
P00766;		289-342
100
Human mesotrypsin complexed with amyloid precursor protein inhibitor(APPI) Heteromer
P35030;		290-341
1009×FMT; 1×CA;
Structure of Human Mesotrypsin in complex with APPI variant T11V/M17R/I18F/F34V Heteromer
P35030;		294-343
92.01×EDO;
Human Mesotrypsin in complex with amyloid precursor protein inhibitor variant APPI-M17G/I18F/F34V Heteromer
P35030;		294-342
93.88
Cryo-EM structure of the human formyl peptide receptor 2 in complex with Abeta42 and Gi2 Heteromer
P04899;P25090;P59768;P62873;		672-713
100.0
Recognition of the Amyloid Precursor Protein by Human gamma-secretase Heteromer
P49768;Q92542;Q96BI3;Q9NZ42;		688-726
100.05×NAG; 1×NAG; 6×NAG; 2×PC1; 3×CLR;
Crystal structure of the intracellular domain of human APP in complex with Fe65-PTB2 Heteromer
O00213;		741-768
100
Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2 Heteromer
O00213;		742-768
96.3
Crystal structure of the intracellular domain of human APP (T668E mutant) in complex with Fe65-PTB2 Heteromer
O00213;		742-768
96.3
Cryo-EM structure of human gamma-secretase in complex with APP-C99 Heteromer
P49768;Q92542;Q96BI3;Q9NZ42;		702-726
96.05×NAG; 1×NAG; 6×NAG; 3×PC1; 3×CLR;
Structure of Alzheimer Ab peptide in complex with an engineered binding protein Heteromer
687-711
100
Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-40) Heteromer
P14735;		672-694
100.01×DIO;
Crystal structure of human insulin-degrading enzyme in complex with amyloid-beta (1-42) Heteromer
P14735;		672-693
100.01×ZN;
Cryo-EM structure of human gamma-secretase in complex with Abeta49 Heteromer
P49768;Q92542;Q96BI3;Q9NZ42;		699-720
95.455×NAG; 1×NAG; 6×NAG; 2×PC1; 2×CLR;
Cryo-EM structure of human gamma-secretase in complex with Abeta46 Heteromer
P49768;Q92542;Q96BI3;Q9NZ42;		696-717
1005×NAG; 1×NAG; 6×NAG; 3×PC1; 2×CLR;
Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloi… Heteromer
P14735;		672-691
100.01×ZN;
ANTIBODY C706 IN COMPLEX WTH BETA-AMYLOID PEPTIDE 1-16 Heteromer
672-687
1004×SO4; 3×GOL;
Fab-amyloid beta fragment complex at neutral pH Heteromer
686-700
86.671×CL; 1×NA;
Crystal Structure of TAP01 in complex with cyclised amyloid beta peptide Heteromer
672-685
85.711×EDO; 1×ZN;
Fab-amyloid beta fragment complex Heteromer
686-699
85.713×EDO; 2×PEG;
Crystal structure of APP peptide bound rat Mint2 PARM Heteromer
O35431;		754-767
100
Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid … Heteromer
P80188;		687-699
100
X11 PTB DOMAIN Heteromer
Q02410;		754-766
100
Structure of Pyroglutamate-Abeta-specific Fab c#24 in complex with human Abeta-pE3-18 Heteromer
674-685
91.67
Crystal Structure of the GULP1 PTB domain-APP peptide complex Heteromer
Q9UBP9;		755-766
1002×SO4; 1×EDO;
Crystal structure of crenezumab Fab in complex with Abeta Heteromer
P0DOX5;Q0KKI6;		684-695
100
CRYSTAL STRUCTURE OF GANTENERUMAB FAB FRAGMENT IN COMPLEX WITH ABETA 1-11 Heteromer
672-682
1001×NAG; 1×SO4;
Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid… Heteromer
P80188;		688-698
100
Crystal Structure of mid-region amyloid beta capture by solanezumab Heteromer
P01834;P01857;		687-697
100
Fab-antibody complex Heteromer
701-711
100
24B3 antibody-peptide complex Heteromer
687-697
90.91
Crystal Structure of TAP01 in complex with amyloid beta peptide Heteromer
674-683
90.01×FLC;
Structure of Pyroglutamate-Abeta-specific Fab c#6 in complex with human Abeta-pE3-12-PEGb Heteromer
674-683
90.01×SO4; 2×GOL;
Crystal structure of MMP-2 active site mutant in complex with APP-drived decapeptide inhibitor Heteromer
P08253;		586-595
1002×ZN; 3×CA;
Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40) Heteromer
Q5JRX3;		686-694
1001×ZN; 1×GOL; 2×ACT;
Design of a split green fluorescent protein for sensing and tracking an beta-amyloid Heteromer
685-693
100
Crystal structure of the complex formed between Phospholipase A2 with beta-amyloid fragment, Lys-Gl… Heteromer
P60045;		699-706
1001×CA;
Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Comple… Heteromer
P60045;		672-679
1001×CA;
X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12A11) complex Heteromer
672-678
100
Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) Heteromer
A2NHM3;P84751;		673-679
100
Crystal structure of Fab WO2 bound to the N terminal domain of Amyloid beta peptide (1-28) Heteromer
A2NHM3;Q811U5;		673-679
100
Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain, in complex wit… Heteromer
O00189;		761-767
1003×GOL;
PFA1 Fab fragment complexed with Abeta 1-8 peptide Heteromer
A2NHM3;		673-679
1002×ACM; 3×GOL;
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex a long aspartimide degron pepti… Heteromer
A4TVL0;		764-770
1001×ZN;
Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, i… Heteromer
O00189;		761-767
100
Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their F… Heteromer
P62993;		756-762
100
Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal A… Heteromer
P60045;		707-713
1001×CA;
Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their F… Heteromer
P62993;		756-762
85.71
Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide Heteromer
P52735;		755-761
100
PFA2 FAB complexed with Abeta1-8 Heteromer
A2NHM3;Q811U5;		673-679
1001×NA;
Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide Fragment of Amyl… Heteromer
P60045;		687-692
1001×CA;
Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid … Heteromer
P80188;		689-694
100
X-ray structure of amyloid beta peptide:antibody (Abeta1-40:12A11) complex Heteromer
673-678
100
Humanised 3D6 Fab complexed to amyloid beta 1-8 Heteromer
672-677
100
Fab fragment of 3D6 in complex with amyloid beta 1-7 Heteromer
672-677
100
X-ray structure of amyloid beta peptide:antibody (Abeta1-7:10D5) complex Heteromer
673-678
100
Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide Heteromer
P01834;P01857;		672-677
100
Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with human Abeta-pE3-12PEGb Heteromer
674-679
83.33
aducanumab abeta complex Heteromer
673-678
1001×SO4;
X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12B4) complex Heteromer
673-678
100
Alzheimer's Amyloid-Beta Peptide Fragment 29-40 in Complex with Cd-substituted Thermolysin Heteromer
P43133;		700-704
1001×CA; 4×CD; 1×DMS;
Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Cd-substituted Thermolysin Heteromer
P43133;		700-704
1003×CA; 2×CD; 1×DMS;
Fab fragment of 3D6 in complex with amyloid beta 1-40 Heteromer
672-676
10027×ZN; 3×IMD; 11×CL;
Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Thermolysin Heteromer
P00800;		702-704
1004×CA; 1×ZN; 1×DMS;
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 4-10 Heteromer
P12821;		678-680
1001×NAG; 1×NAG; 1×NAG; 1×ZN; 1×CL; 1×SO4; 4×PEG;
Structure of Human Neurolysin (E475Q) in complex with amyloid-beta 35-40 peptide product Heteromer
Q9BYT8;		709-711
1001×ZN; 1×CL;
CryoEM structure of human presequence protease in partial closed state 1 Heteromer
Q5JRX3;		690-692
100
Crystal structure of the Angiotensin-1 converting enzyme N-domain in complex with amyloid-beta 35-42 Heteromer
P12821;		712-713
1001×NAG; 1×NAG; 1×NAG; 1×ZN; 1×CL; 3×PEG; 1×PG4; 1×P6G;
J-shaped conformer of amyloid beta (1-40)homo-40-mer672-711
100
Atomic model of the Abeta D23N "Iowa" mutant using solid-state NMR, EM and Rosetta modelinghomo-27-mer686-711
96.15
Type IIIb beta-amyloid 40 Filaments from Down Syndromehomo-20-mer672-711
100
Amyloid-beta 40 type 2 filament from the leptomeninges of individual with Alzheimer's disease and c…homo-20-mer672-709
100
Type Id amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaqueshomo-20-mer680-713
100
Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaqueshomo-20-mer680-713
100
Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Negative Staggerhomo-18-mer680-711
100
Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Positive Staggerhomo-18-mer680-711
100
Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrilshomo-18-mer682-713
100
Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrilshomo-16-mer682-713
100
Mixing Abeta(1-40) and Abeta(1-42) peptides generates unique amyloid fibrilshomo-16-mer682-713
100
A New Structural Model of Abeta(1-40) Fibrilshomo-16-mer682-711
100
Abeta fibril (Morphology I)homo-12-mer672-711
100
seeded Abeta(1-40) amyloid fibril (morphology I)homo-12-mer672-708
100
The cryo-EM structure of AV-45 bound type1 amyloid beta 42 fibril.homo-12-mer680-713
1002×VW6;
Structural Model for a 40-Residue Beta-Amyloid Fibril with Two-Fold Symmetry, Negative Staggerhomo-12-mer680-711
100
42-Residue Beta Amyloid Fibrilhomo-12-mer682-713
100
Structural Model for a 40-Residue Beta-Amyloid Fibril with Two-Fold Symmetry, Positive Staggerhomo-12-mer680-711
100
Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains |…homo-12-mer682-711
96.3
unseeded Abeta(1-40) amyloid fibril (morphology ii)homo-12-mer684-711
100
unseeded Abeta(1-40) amyloid fibril (morphology i)homo-12-mer684-711
100
Covalently stabilized triangular trimer composed of Abeta17-36 beta-hairpinshomo-12-mer687-707
80.95
Triangular trimer of beta-hairpins derived from Abeta17-36 with an F20Cha mutationhomo-12-mer686-706
71.43
X-ray crystallographic structure of an Abeta 17-36 beta-hairpin. LV(PHI)FAEDCGSNKCAII(SAR)L(ORN)Vhomo-12-mer688-707
85.0
X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. X-ray diffractometer data set. (L…homo-12-mer688-707
90.02×JEF;
Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutationhomo-12-mer687-697
90.91
Structure of an amyloid forming peptide GAIIGL (29-34) from amyloid betahomo-12-mer700-705
100
Structure of an amyloid forming peptide KLVFFA from amyloid beta, alternate polymorph IIhomo-12-mer687-692
100
Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutationhomo-10-mer672-711
100
Lipidic amyloid-beta(1-40) fibril - polymorph L1homo-10-mer672-711
100
Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3homo-10-mer672-711
100
S8 phosphorylated beta amyloid 40 fibrilshomo-10-mer672-711
10010×2PO;
Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3homo-10-mer672-711
100
Sarkosyl-extracted AppNL-G-F Abeta42 fibril structurehomo-10-mer672-709
97.37
Sarkosyl-extracted AppNL-G-F Abeta42 fibril structure (Methoxy-X04-labelled mice)homo-10-mer672-709
97.37
Amyloid-beta (1-40) fibrils derived from a CAA patienthomo-10-mer672-709
100
DI1 Abeta fibril from tg-SwDI mousehomo-10-mer672-707
94.44
Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2homo-10-mer676-711
100
Type I beta-amyloid 42 Filaments from Human Brainhomo-10-mer680-713
10010×UNX;
Type I beta-amyloid 42 Filaments from Down syndromehomo-10-mer680-713
100
Murine type III Abeta fibril from APP/PS1 mousehomo-10-mer681-713
100
MurineArc type I Abeta fibril from tg-APPArcSwe mousehomo-10-mer680-711
96.88
Type IIIa beta-amyloid 40 Filaments from Down syndromehomo-10-mer680-711
100
Murine type III Abeta fibril from ARTE10 mousehomo-10-mer681-711
100
Murine type II Abeta fibril from ARTE10 mousehomo-10-mer683-713
100
Murine type II Abeta fibril from tgAPPSwe mousehomo-10-mer683-713
100
Murine type II Abeta fibril from APP23 mousehomo-10-mer683-713
100
Type II beta-amyloid 42 Filaments from Human Brainhomo-10-mer683-713
10010×UNX;
Amyloid-Beta (20-34) with L-isoaspartate 23homo-10-mer691-705
100
VGSNKGAIIGL from Amyloid Beta determined by MicroEDhomo-10-mer695-705
100
Near-atomic resolution fibril structure of complete amyloid-beta(1-42) by cryo-EMhomo-9-mer672-713
100
40-residue beta-amyloid fibril derived from Alzheimer's disease brainhomo-9-mer672-711
100
The cryo-EM structure of AV-45 bound type3 amyloid beta 42 fibril.homo-9-mer680-713
100
The cryo-EM structure of type3 amyloid beta 42 fibril.homo-9-mer680-713
100
Brain-derived 42-residue amyloid-beta fibril type Bhomo-8-mer672-713
100
Brain-derived 42-residue amyloid-beta fibril type Ahomo-8-mer683-713
100
Amyloid-beta assemblage on GM1-containing membraneshomo-8-mer683-711
100
40-residue D23N beta amyloid fibrilhomo-8-mer686-711
96.15
X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 16-36homo-8-mer685-706
81.827×HEZ;
Structure of amyloid-beta derived peptide - NKGAIFhomo-8-mer698-703
83.338×PO4;
Amyloid beta oligomer displayed on the alpha hemolysin scaffoldhomo-7-mer672-713
100
Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibrilhomo-6-mer672-713
100
Cryo-EM structure of the fibril formed by disaccharide-modified amyloid-beta(1-42)homo-6-mer677-713
1006×X6X; 6×ACY;
The cryo-EM structure of type1 amyloid beta 42 fibril.homo-6-mer680-713
100
The cryo-EM structure of type1 amyloid beta 42 fibril in AD3.homo-6-mer680-713
100
The cryo-EM structure of type1 amyloid beta 42 fibril in AD2 patient.homo-6-mer680-713
100
Type I amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's d…homo-6-mer680-713
100
Ab typeII filament from Guam ALS/PDChomo-6-mer683-713
100
Amyloid-beta(1-40) fibril derived from Alzheimer's disease cortical tissuehomo-6-mer681-711
100
Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's…homo-6-mer683-713
96.77
Type II amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's …homo-6-mer683-713
100
Amyloid-beta (1-40) fibrils derived from familial Dutch-type CAA patient (population B)homo-6-mer686-710
100
Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, include…homo-6-mer706-711
1006×YWK;
Structure of an amyloid forming peptide NKGAII (residues 27-32) from amyloid betahomo-6-mer698-703
100
Racemic mixture of amyloid beta segment 16-KLVFFA-21 forms heterochiral rippled beta-sheethomo-6-mer687-692
1006×TFA;
Lipidic amyloid-beta(1-40) fibril - polymorph L3homo-5-mer672-711
100
DI2 Abeta fibril from tg-SwDI mousehomo-5-mer672-710
94.87
Lipidic amyloid-beta(1-40) fibril - polymorph L2homo-5-mer676-711
100
DI3 Abeta fibril from tg-SwDI mousehomo-5-mer673-704
93.75
3D Structure of Alzheimer's Abeta(1-42) fibrilshomo-5-mer688-713
100
Amyloid-Beta (20-34) wild typehomo-5-mer691-705
100
Structure of pore-forming amyloid-beta tetramershomo-4-mer672-713
100
Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymor…homo-4-mer706-713
100
Structure of an amyloid forming peptide KLVFFA from amyloid beta in complex with orange Ghomo-4-mer687-692
1002×ORA;
Structure of segment AIIGLM from the amyloid-beta peptide (Ab, residues 30-35)homo-4-mer701-706
100
X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGS…homo-3-mer688-707
90.0
A receptor moleculehomo-2-mer385-624
1001×SGN; 6×ZN; 1×CA; 3×GOL; 1×ACT; 3×SCN; 1×SO4; 1×MG;
The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domainhomo-2-mer371-566
100
Crystal Structure Analysis of APP E2 domainhomo-2-mer379-559
1002×OS;
Structure of the Heparin-induced E1-Dimer of the Amyloid Precursor Protein (APP)homo-2-mer26-190
1002×BU4; 1×SO4; 1×ACT;
X-RAY CRYSTAL STRUCTURE OF THE PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECUR…homo-2-mer287-342
100
Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environmenthomo-2-mer686-726
100
X-ray crystallographic structure of a beta-hairpin peptide derived from amyloid beta 14-40homo-2-mer682-711
83.331×CL;
Solution NMR structure of transmembrane domain of amyloid precursor protein WThomo-2-mer699-726
100
Solution NMR structure of transmembrane domain of amyloid precursor protein V44Mhomo-2-mer699-726
96.43
Electron cryo-microscopy of an Abeta(1-42)amyloid fibrilhomo-2-mer686-713
100
Beta hairpin derived from Abeta17-36 with an F20Cha mutationhomo-2-mer686-706
80.952×CL; 1×NA;
Zinc induced dimer of the metal binding domain 1-16 of human amyloid beta-peptide with Alzheimer's …homo-2-mer672-687
93.751×ZN;
Zinc bound dimer of the fragment of human amyloid-beta peptide with Alzheimer's disease pathogenic …homo-2-mer672-681
90.02×ZN;
Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymor…homo-2-mer706-713
100
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with coppermonomer384-567
1001×ACT; 2×CU; 7×CD;
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with zincmonomer385-567
1001×ACT; 1×ZN; 8×CD;
X-ray structure of the E2 domain of the human amyloid precursor protein (APP) in complex with cadmi…monomer388-567
1002×ACT; 9×CD;
HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE E1-DOMAIN of THE AMYLOID PRECURSOR PROTEINmonomer28-189
100
Solution structure of CAPPD*, an independently folded extracellular domain of human Amyloid-beta Pr…monomer460-569
100
The longer crystal structure of the grow factor like domain from Beta amypoid precusor protein (APP…monomer22-126
100
Crystal structure of the N-terminal, growth factor-like domain of the amyloid precursor protein bou…monomer23-123
1001×CU; 1×GOL;
N-TERMINAL DOMAIN OF THE AMYLOID PRECURSOR PROTEINmonomer28-123
100
Structure of the Alzheimer's disease amyloid precursor protein copper binding domainmonomer124-189
100
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain (Residues 126- 1…monomer126-189
100
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit c…monomer133-189
1001×GOL;
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit c…monomer133-189
1001×CU;
Structure of the Alzheimer's Amyloid Precursor Protein (APP) copper binding domain (residues 133 to…monomer133-189
100
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit c…monomer133-189
1001×CU1;
Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'large unit c…monomer133-189
1004×CU;
Dynamic complex between all-D-enantiomeric peptide D3 with wild-type amyloid precursor protein 672-…monomer672-726
100
Dynamic complex between all-D-enantiomeric peptide D3 with L723P mutant of amyloid precursor protei…monomer672-726
98.18
The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein …monomer683-728
100
Aqueous Solution Structure of the Alzheimer's Disease Abeta Peptide (1-42)monomer672-713
100
Solution structure of the Alzheimer's disease amyloid beta-peptide (1-42)monomer672-713
100
Solution structure of the amyloid beta-peptide (1-42)monomer672-713
100
Structure of amyloid precursor protein's transmembrane domainmonomer686-726
100
THE SOLUTION STRUCTURE OF AMYLOID BETA-PEPTIDE (1-40) IN A WATER-MICELLE ENVIRONMENT. IS THE MEMBRA…monomer672-711
100
3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-vi…monomer672-711
1002×23Y;
SOLUTION STRUCTURE OF THE METHIONINE-OXIDIZED AMYLOID BETA-PEPTIDE (1-40). DOES OXIDATION AFFECT CO…monomer672-711
100
A partially folded structure of amyloid-beta(1 40) in an aqueous environmentmonomer672-711
100
3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-vi…monomer672-711
1002×23Y;
THE ALZHEIMER`S DISEASE AMYLOID A4 PEPTIDE (RESIDUES 1-40)monomer672-711
100
Amyloid-beta 40 type 1 filament from the leptomeninges of individual with Alzheimer's disease and c…monomer672-709
100
Solution NMR Structure of APP V44M mutant TMDmonomer697-726
96.67
Solution NMR Structure of APP I45T mutant TMDmonomer697-726
96.67
Solution NMR Structure of APP G38L mutant TMDmonomer697-726
96.67
Solution NMR Structure of APP G38P mutant TMmonomer697-726
96.67
Solution NMR Structure of APP TMDmonomer697-726
100
SOLUTION NMR STRUCTURE OF AMYLOID BETA[E16], RESIDUES 1-28, 14 STRUCTURESmonomer672-699
96.43
SOLUTION NMR STRUCTURE OF AMYLOID BETA[F16], RESIDUES 1-28, 15 STRUCTURESmonomer672-699
96.43
SOLUTION STRUCTURE OF RESIDUES 1-28 OF THE AMYLOID BETA-PEPTIDEmonomer672-699
100
SOLUTION STRUCTURE OF RESIDUES 1-28 OF THE AMYLOID BETA-PEPTIDEmonomer672-699
100
ALZHEIMER'S DISEASE AMYLOID-BETA PEPTIDE (RESIDUES 10-35)monomer681-706
100
Amyloid beta(18-41) peptide fusion with new antigen receptor variable domain from sharksmonomer689-712
100
Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-a…monomer672-694
1001×CU;
Molecular structure of Cu(II)-bound amyloid-beta monomer implicated in inhibition of peptide self-a…monomer672-694
1001×CU;
NMR structure of the soluble A beta 17-34 peptidemonomer688-705
100
Zinc-binding domain of Alzheimer's disease amyloid beta-peptide in water solution at pH 6.5monomer672-687
100
Zinc-binding domain of Alzheimer's disease amyloid beta-peptide in TFE-water (80-20) solutionmonomer672-687
100
Zinc-binding domain of Alzheimer's disease amyloid beta-peptide complexed with a zinc (II) cationmonomer672-687
1001×ZN;
NMR analysis of 25-35 fragment of beta amyloid peptidemonomer696-706
100
NMR structure of the fragment 25-35 of beta amyloid peptide in 20/80 v:v hexafluoroisopropanol/wate…monomer696-706
100
Solution structure of fragment (25-35) of beta amyloid peptide in SDS micellar solutionmonomer696-706
100
AMYLOID BETA PEPTIDE (25-35), NMR, 20 STRUCTURESmonomer696-706
100
Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph…monomer687-692
1001×ACT;
Structure of segment KLVFFA from the amyloid-beta peptide (Ab, residues 16-21), alternate polymorph…monomer687-692
100

3 SWISS-MODEL models

TemplateOligo-stateQMEANDisCoRangeLigandsTrg-Tpl Seq id (%)
7mrm.1.Amonomer0.7430-189
93.57
6har.1.Bmonomer0.62294-342
90.57
2ysz.1.Amonomer0.53733-770
84.21

Model IDOligo-stateAvg pLDDTRangeTrg-Mdl Seq Id (%)

Model IDOligo-stateAvg ConfidenceRangeTrg-Mdl Seq id (%)

25 SWISS-MODEL models built on isoform sequence

IsoformTemplateOligo-stateQMEANDisCoRangeLigandsTrg-Tpl Seq id (%)
Isoform 23ktm.1.Bmonomer0.7526-190
1×BU4;100.00
Isoform 37mrm.1.Amonomer0.7330-189
93.57
Isoform 32ysz.1.Amonomer0.60640-677
84.21
Isoform 47mrm.1.Amonomer0.7230-189
93.57
Isoform 42ysz.1.Amonomer0.56658-695
84.21
Isoform 55tpt.1.Amonomer0.72318-514
67.51
Isoform 57mrm.1.Amonomer0.7030-189
93.57
Isoform 52ysz.1.Amonomer0.55659-696
84.21
Isoform 67mrm.1.Amonomer0.7230-189
93.57
Isoform 65tpt.1.Amonomer0.71318-514
67.51
Isoform 62ysz.1.Amonomer0.51677-714
84.21
Isoform 77mrm.1.Amonomer0.7230-189
93.57
Isoform 75nx3.1.Dmonomer0.69289-341
92.86
Isoform 72ysz.1.Amonomer0.53696-733
84.21
Isoform 87mrm.1.Amonomer0.7530-189
93.57
Isoform 85nx3.1.Dmonomer0.69289-341
92.86
Isoform 82ysz.1.Amonomer0.53714-751
84.21
Isoform 97mrm.1.Amonomer0.7630-189
93.57
Isoform 96har.1.Bmonomer0.70294-342
90.57
Isoform 92ysz.1.Amonomer0.54715-752
84.21
Isoform 105tpt.1.Amonomer0.70243-439
67.51
Isoform 107mrm.1.Bmonomer0.6612-134
88.19
Isoform 117mrm.1.Amonomer0.7525-184
93.53
Isoform 115nx3.1.Dmonomer0.69284-336
92.86
Isoform 112ysz.1.Amonomer0.53709-746
84.21

Alignments

SWISS-MODEL based on, SMTL Version; Trg-Tpl Seq Id.

Average Model Confidence (QMEANDisCo):;Local Confidence
Average Model Confidence () :-;Local Confidence
:."". Released.

We predict this structure to be a membrane protein.

Export Alignment
Colour Scheme
Background
3D Viewer
[8]ページ先頭
©2009-2025 Movatter.jp