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votes
5
replies
2.2k
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DESeq2 contrast cleaning problem
software error
bugs
deseq2
written 10.0 years ago by
john.hu
• 0
0
votes
3
replies
2.4k
views
PCA outliers cleaning
scRNAseq
Pipeline
Seurat
SingleCellExperiment
written 6.3 years ago by
albadrs.93
▴ 10
1
vote
2
replies
2.8k
views
Cleaning GeneSets from GSEA
msigdb
GSEABase
GSVA
written 3.9 years ago by
forlani.luca
• 0
0
votes
1
reply
73
views
soGGi error
soGGi
updated 2 days ago by
shepherl
4.3k • written 2 days ago by
Daniel
• 0
0
votes
1
reply
92
views
Chip Seq Analysis of RNA Polymerase 2
ChIPseeker
ChIPSeqData
ChIPSeq
Bioconductor
written 3 days ago by
Gaurav
• 0
5
votes
3
replies
558
views
Limma-voom sample weights and impact on DEG numbers
limma
written 6 weeks ago by
A.Barden
▴ 20
0
votes
1
reply
97
views
Job:
Postdoctoral Fellow (Computational Biology / Bioinformatics) - Neuroepigenetics (MSCA PF / EMBO)
Epigenetics
JobPosting
Neuroscience
updated 16 hours ago by
mudasarnaeem2020
• 0 • written 4 days ago by
lalit.kaurani
• 0
0
votes
1
reply
117
views
News:
The Call for Abstracts for BioC2026 is open!
Bioconductor
Conference
written 4 days ago by
laurah ondari
• 0
0
votes
3
replies
271
views
Confirm that OpenStats will not be archived (pryr dependency)
OpenStats
written 11 days ago by
Marina
• 0
0
votes
15
replies
1.5k
views
Species level information couldn't find with DADA2 bioconductor package
Metagenomics
dada2
MicrobiomeData
written 19 months ago by
abhisek001
• 0
20
votes
6
replies
11k
views
Tutorial:
Updated Support Site Editor
support.bioconductor.org
editor
markdown
updates
Tutorial
written 7.0 years ago by
shepherl
4.3k
0
votes
0
replies
14
views
Spam:
PokeChill
customCMPdb
AMOUNTAIN
5 days ago
play
0
0
votes
1
reply
2.6k
views
Tutorial:
[LIBD rstats club] Bioconductor overview
bioconductor
libdrstats
Tutorial
written 5.8 years ago by
Leonardo Collado Torres
★ 1.1k
0
votes
1
reply
129
views
msmsTests, inconsistent sign between lFC.Av and LogFC
msmsTests
Proteomics
8 days ago
Ben
• 0
0
votes
1
reply
126
views
DESeq2 for 16S rRNA Analysis
DESeq2
updated 8 days ago by
James W. MacDonald
68k • written 8 days ago by
lizflor
• 0
0
votes
0
replies
83
views
News:
Deadline Extended: EuroBioC2026 Call for Abstracts
Bioconductor
Conference
8 days ago
laurah ondari
• 0
0
votes
3
replies
1.5k
views
ChAMP trouble reading csv file
ChAMP
written 2.5 years ago by
Keasiykan
• 0
0
votes
0
replies
58
views
bcftools norm Equivalent
Rsamtools
10 days ago
Dario Strbenac
★ 1.6k
0
votes
5
replies
244
views
Lowly expressed genes reported as significant when using lfcThreshold in DESeq
RNASeq
DESeq2
DifferentialExpression
updated 11 days ago by
Michael Love
43k • written 11 days ago by
Ahmed Salah
• 0
0
votes
2
replies
193
views
lfc shrinkage estimator in DESeq2
DESeq2
written 12 days ago by
julia_mcdonough
• 0
2
votes
1
reply
181
views
Array weights in dpcDE
limpa
updated 11 days ago by
Gordon Smyth
53k • written 12 days ago by
Matt
• 0
0
votes
2
replies
150
views
Justify title track when rotation = 0
Gviz
gviz
written 17 days ago by
Xenia
• 0
0
votes
2
replies
179
views
Bile acid analysis with limpa
limpa
MassSpectrometry
MassSpectrometryData
updated 13 days ago by
Gordon Smyth
53k • written 16 days ago by
DN
• 0
0
votes
13
replies
815
views
Making a Full Rank Model for Allele-Specific Expression with DESeq2
DESeq2
updated 12 days ago by
Gordon Smyth
53k • written 18 days ago by
chp265
• 0
0
votes
1
reply
155
views
Changing multiple display parameters of a specific exon in GeneRegionTrack
Gviz
written 17 days ago by
Xenia
• 0
0
votes
2
replies
291
views
Are individual-mouse-based statistics possible in CellChat?
Bioconductor
CellChat
updated 14 days ago by
LillianaVolkman99
• 0 • written 24 days ago by
Omer
• 0
0
votes
6
replies
620
views
BiocParallel (and DESeq2) - wrong args for environment subassignment
BiocParallel
DESeq2
updated 19 days ago by
Martin Morgan
25k • written 9 weeks ago by
Benjamin
• 0
0
votes
1
reply
271
views
DESeq2 - how to shrink LFC for pairwise comparisons having multiple groups
shrinkage
DESeq2
contrast
updated 18 days ago by
ATpoint
★ 5.0k • written 21 days ago by
ja569116
• 0
2
votes
6
replies
489
views
limpa analysis advice
limpa
updated 10 days ago by
Gordon Smyth
53k • written 22 days ago by
SamGG
▴ 360
0
votes
1
reply
140
views
News:
The BioC2026 Sticker Design Contest is Open!
Bioconductor
Conference
written 22 days ago by
laurah ondari
• 0
4
votes
2
replies
350
views
When to use edgeR or limma
edgeR
limma
updated 22 days ago by
Gordon Smyth
53k • written 24 days ago by
abzhang97
• 0
1
vote
3
replies
234
views
Incosistencies in buildSNNGraph() function
scran
seurat
written 28 days ago by
Lucas
• 0
0
votes
2
replies
1.0k
views
A problem occurs when running the monocle2
monocle
written 4 months ago by
yuheng_yang
• 0
0
votes
7
replies
548
views
limpa-blank normalization and Spectronaut's PTM stoichiometry
limpa
updated 16 days ago by
Gordon Smyth
53k • written 24 days ago by
emily.wolfrum
• 0
0
votes
2
replies
169
views
Questions about bacon QC and correction on EWAS results
bacon
written 24 days ago by
sup0903
• 0
3
votes
4
replies
345
views
Question about the filterByExpr function inputs in edgeR
RNASeq
filter
design
edgeR
model.matrix
25 days ago • updated 23 days ago
mohammedtoufiq91
▴ 10
0
votes
1
reply
154
views
Development of MSstat workflow to analyze DIA time series data
MSstats
updated 24 days ago by
Gordon Smyth
53k • written 25 days ago by
sithurandi
• 0
0
votes
0
replies
301
views
MSstatsPTM-SpectronauttoMSstatsPTMFormat-failing with TAIR10 Locus Tags: Issue with UniProt-centric protein ID parsing
Bioconductor
MSstatsPTM
25 days ago
srkingwu
• 0
8
votes
8
replies
2.9k
views
Confounded design, batch effect correction (edgeR)
rnaseq
edger
differential gene expression
batch effect
written 7.4 years ago by
Laura
▴ 20
0
votes
1
reply
129
views
Junction CPM via Snapcount and Recount3
snapcount
recount3
written 26 days ago by
henry.tietz
• 0
3
votes
4
replies
463
views
Clarification on counting in Rsubread (featureCounts)
featureCounts
Rsubread
updated 25 days ago by
Gordon Smyth
53k • written 7 weeks ago by
Luca
• 0
0
votes
1
reply
132
views
News:
Online RNA-seq analysis course 26-29th Janury
EnhancedVolcano
GSEABase
pheatmap
Workshop
DESeq2
written 26 days ago by
Frances Turner
▴ 20
0
votes
1
reply
154
views
How to convert .raw data for use in xcms
xcms
written 26 days ago by
Monica
• 0
0
votes
1
reply
353
views
Job:
Open Positions for Doctoral Researchers in Molecular Medicine
JobPosting
written 26 days ago by
rubina.tabassum
• 0
1
vote
1
reply
179
views
News:
Bioconductor Maintainer Application
maintainer
policy
Bioconductor
Devel
devel
written 29 days ago by
shepherl
4.3k
0
votes
1
reply
495
views
News:
GSEA in R/Bioconductor course
GSEABenchmarkeR
pairedGSEA
GeneSetEnrichment
written 11 months ago by
info
▴ 10
0
votes
1
reply
382
views
News:
Announcing a New Journal - Bioinformatics Methods and Applications - Now Open for Submissions
Bioconductor
written 7 months ago by
Wei Shi
★ 3.6k
0
votes
2
replies
2.5k
views
ChAMP pipeline error (champ.import)
software error
written 6.8 years ago by
mhebba
• 0
0
votes
2
replies
346
views
Combining two proteomics datasets with limpa
limpa
ProteomicsWorkflow
limma
4 weeks ago • updated 16 days ago
Andrew Pattison
• 0
0
votes
0
replies
180
views
Job:
Jobs at Ensembl
ensembldb
4 weeks ago
Aleena_Ensembl
▴ 30
46,743 results • Page
1 of 935
Recent ...
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Comment: GOseq Probability Weight Function bad fit
by
a2sahaaaq2c
• 0
the mobile gaming world offers a different kind of strategic challenge. Many users today are shifting from heavy data processing to lighthe…
Comment: Postdoctoral Fellow (Computational Biology / Bioinformatics) - Neuroepigenetics
by
mudasarnaeem2020
• 0
Promoting UDISE+ Features on Social Media to Increase Awarenesshttps://udisseplus.com/[enter link description here][1] [1]: https://ud…
Comment: DiffBind plot.profile error
by
a2sahaaaq2c
• 0
To resolve technical errors like installation failures or login issues, first ensure your device allows in the security settings and that…
Comment: soGGi error
by
shepherl
4.3k
We have tried to contact the soGGi maintainer to have them update the package to the newer version of gglot2 but they have so far been unre…
Comment: using limma trend workflow in CAMERA
by
Gordon Smyth
53k
No, `trend.var=TRUE` and `trend=TRUE` are not needed in any voom pipeline, because the trend is already incorporated into the voom weights.
Votes
Answer: DiffBind differential analysis
Answer: Limma-voom sample weights and impact on DEG numbers
C: Why limma, edgeR, and DESeq did not implement fold change moderation first?
Comment: using limma trend workflow in CAMERA
C: z-score with DESeq2?
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