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Receptor slobodnih masnih kiselina

С Википедије, слободне енциклопедије

Receptor slobodnih masnih kiselina 1
Identifikatori
Simbol	FFAR1, FFA1R
Alt. simboli	GPR40
Entrez	2864
HUGO	4498
OMIM	603820
RefSeq	NM_005303
UniProt	O14842
Ostali podaci
Lokus	Hromozom 19q13.1

Receptor slobodnih masnih kiselina 2
Identifikatori
Simbol	FFAR2
Alt. simboli	GPR43, FFA2R
Entrez	2867
HUGO	4501
OMIM	603823
RefSeq	NM_005306
UniProt	O15552
Ostali podaci
Lokus	Hromozom 19q13.1

Receptor slobodnih masnih kiselina 3
Identifikatori
Simbol	FFAR3
Alt. simboli	GPR41, FFA3R
Entrez	2865
HUGO	4499
OMIM	603821
RefSeq	NM_005304
UniProt	O14843
Ostali podaci
Lokus	Hromozom 19q13.1

G protein-spregnuti receptor 42
Identifikatori
Simbol	GPR42
Alt. simboli	GPR41L, FFAR1L
Entrez	2866
HUGO	4500
OMIM	603822
RefSeq	NM_005305
UniProt	O15529
Ostali podaci
Lokus	Hromozom 19q31.1

Receptor slobodnih masnih kiselina jeG-protein spregnuti receptor vezujeslobodne masne kiseline.^[1] Postoje četiri varijante ovog receptora, koje su kodirane zasebnim genima (FFAR1,FFAR2,FFAR3,GPR42)^[2].

^Covington DK, Briscoe CA, Brown AJ, Jayawickreme CK (2006). „The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing”.Biochem. Soc. Trans.34 (Pt 5): 770—3.PMID 17052194.doi:10.1042/BST0340770.
^R. Lee Kennedy, Venkat Vangaveti, Ghassan Jarrod, Venkatesh Shashidhar, Venkatesh Shashidhar, Bernhard T. Baune (2010).„Review: Free fatty acid receptors: emerging targets for treatment of diabetes and its complications”.Therapeutic Advances in Endocrinology and Metabolism October. SAGE.1 (4): 165—175.doi:10.1177/2042018810381066. Архивирано изоригинала 28. 10. 2014. г. Приступљено06. 03. 2011. CS1 одржавање: Вишеструка имена: списак аутора (веза)

„Free Fatty Acid Receptors”.IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Архивирано изоригинала 03. 03. 2016. г.
FFAR1+protein,+human наUS National Library of Medicine Medical Subject Headings (MeSH)
G-protein+coupled+receptor+43,+human наUS National Library of Medicine Medical Subject Headings (MeSH)
FFAR3+protein,+human наUS National Library of Medicine Medical Subject Headings (MeSH)

Adrenergički	α1 (A,B,D) • α2 (A,B,C) • β1 • β2 • β3
Purinski	Adenozinski (A1,A2A,A2B,A3) • P2Y (1,2,4,5,6,8,9,10,11,12,13,14)
Serotoninski	(svi osim 5-HT3)5-HT1 (A,B,D,E,F) • 5-HT2 (A,B,C) • 5-HT (4,5A,6,7)
Drugi	Acetilholin (M1,M2,M3,M4,M5) • Dopamin (D1,D2,D3,D4,D5) • Histamin (H1,H2,H3,H4) • Melatonin (1A,1B,1C) • TAAR (1,2,3,5,6,8,9)

Metaboliti i
signalni molekuli

Eikozanoidni	CysLT (1,2) • LTB4 (1,2) • FPRL1 • OXE • Prostaglandin (DP (1,2),EP (1,2,3,4),FP) • Prostaciklin • Tromboksan
Drugi	Žučna kiselina • Kanabinoidni (CB1,CB2,GPR (18,55,119)) • EBI2 • Estrogen • Slobodna masna kiselina (1,2,3,4) • Laktat • Lizofosfatidna kiselina (1,2,3,4,5,6) • Lizofosfolipid (1,2,3,4,5,6,7,8) • Niacin (1,2) • Oksoglutarat • PAF • Sfingozin-1-fosfat (1,2,3,4,5) • Sukcinat

Peptid

B/W (1,2) • FF (1,2) • S • Y (1,2,4,5) • Neuromedin (B,U (1,2)) • Neurotenzin (1,2)

Drugi

Razno

Orfan	GPR (1,3,4,6,12,15,17,18,19,20,21,22,23,25,26,27,31,32,33,34,35,37,39,42,44,45,50,52,55,61,62,63,65,68,75,77,78,81,82,83,84,85,87,88,92,101,103,109A,109B,119,120,132,135,137B,139,141,142,146,148,149,150,151,152,153,160,161,162,171,173,174,176,177,182,183)
Drugi	Adrenomedulin • Mirisni • Opsin (3,4,5,1LW,1MW,1SW,RGR,RRH) • Proteazom-aktivirani (1,2,3,4) • SREB (1,2,3)

Orfan	GPR (56,64,97,98,110,111,112,113,114,115,116,123,124,125,126,128,133,143,144,155,157)
Drugi	Moždano specifični angiogenezni inhibitor (1,2,3) • Kadherin (1,2,3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1,2) • EMR (1,2,3) • Glukagon (GR,GIPR,GLP1R,GLP2R) • Hormon rasta • PACAPR1 • GPR • Latrofilin (1,2,3,ELTD1) • Metuzalemski protein • Paratiroidni hormon (1,2) • Sekretin • Vazoaktivni intestinalni peptid (1,2)

Ukus	TAS1R (1,2,3) • TAS2R (1,3,4,5,8,9,10,12,13,14,16,19,20,30,31,38,39,40,41,42,43,45,46,50)
Drugi	Kalcijum-detektujući receptor • GABA B (1,2) • Glutamatni receptor (Metabotropni glutamat (1,2,3,4,5,6,7,8)) • GPRC6A • GPR (156,158,179) • RAIG (1,2,3,4) • VNR (1,2,3,5)

Uvojiti	Frizzled (1,2,3,4,5,6,7,8,9,10)
Zaglađeni	Zaglađeni

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