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Gonadotropin-releasing hormone

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(Redirected fromGnRH)

Gonadotropin-releasing hormone (GnRH), orLuteinizing-hormone-releasing hormone (LHRH), is ahormone synthesized and released fromneurons in thehypothalamus.

GnRH occurs in allvertebrates. This single hormone controls all the complex processes which prepare the male and female for successful reproduction.

GnRH releasesfollicle-stimulating hormone (FSH) andluteinizing hormone (LH) from theanterior pituitary.

GnRH activity is very low during childhood, and is activated atpuberty oradolescence. During the reproductive years, it is critical for successful reproductive function as controlled by feedback loops. However, once apregnancy is established, GnRH activity is not required.

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Hormones

Endocrine
glands

Hypothalamic-
pituitary

Hypothalamus	GnRH Dopamine TRH CRH GHRH Somatostatin (GHIH) MCH
Posterior pituitary	Oxytocin Vasopressin
Anterior pituitary	FSH LH TSH GH POMC CLIP ACTH MSH Endorphins Lipotropin Prolactin