Tripsin (EC3.4.21.4,alfa-tripsin,beta-tripsin,kokunaza,parenzim,parenzimol,triptar,tripur,pseudotripsin,tripcelim,sperm receptorska hidrolaza) jeenzim.[1][2][3][4][5][6][7] Ovaj enzimkatalizuje sledećuhemijsku reakciju
- Preferentno odvajanje: Arg-, Lys-
Jednolančani polipeptid goveđeg beta-tripsina se formira iz tripsinogena razlaganjem jedne peptidne veze.
- ↑Huber, R. and Bode, W. (1978). „Structural basis of the activation and action of trypsin”. Acc. Chem. Res. 11: 114-122.
- ↑Walsh, K.A. (1970). „Trypsinogens and trypsins of various species”. Methods Enzymol. 19: 41-63.
- ↑Read, R.J., Brayer, G.D., Jurásek, L. and James, M.N.G. (1984). „Critical evaluation of comparative model building ofStreptomyces griseus trypsin”. Biochemistry 23: 6570-6575. PMID 6442164.
- ↑Fiedler, F. (1987). „Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin”. Eur. J. Biochem. 163: 303-312. PMID 3643848.
- ↑Fletcher, T.S., Alhadeff, M., Craik, C.S. and Largman, C. (1987). „Isolation and characterization of a cDNA encoding rat cationic trypsinogen”. Biochemistry 26: 3081-3086. PMID 3112218.
- ↑Polgár, L. (1987). „Structure and function of serine proteases”. u: Neuberger, A. and Brocklehurst, K.. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. str. 159-200.
- ↑Tani, T., Kawashima, I., Mita, K. and Takiguchi, Y. (1990). „Nucleotide sequence of the human pancreatic trypsinogen III cDNA”. Nucleic Acids Res. 18: 1631-1631. PMID 2326201.
- Polgár, L. (1987). „Structure and function of serine proteases”. u: Neuberger, A. and Brocklehurst, K.. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. str. 159-200.