Biomaterials for treating skin loss
This book provides a comprehensive review of biomaterials for treating skin loss. The primary causes of wounds requiring skin replacement are severe burns and ulcers. Materials must provide an effective temporary barrier, promote healing and minimise scarring. Massive improvements have been made to skin repair biomaterials in the last ten years with widespread adoption of new developments in the medical sector. This book provides a comprehensive review of the range of biomaterials for treating skin loss. Part one discusses the basics of skin replacement with chapters on such topics as markets and regulation, biomechanics and the biological environment of skin. Part two then reviews epidermal and dermal replacement technology with chapters on such topics as alternative delivery of keratinocytes, collagen-based and human origin-based dermal replacement, and lyophilized xenogenic products. The final section explores combined dermis and epidermal replacement technol
1 online resource
9781845695545, 1845695542
844452405
Part 1 Introduction: Development of skin substitutes
Skin replacement products and markets
Biomechanics of skin
The pathophysiologic basis for wound healing and cutaneous regeneration
Skin grafts
Understanding the cellular basis of skin growth
The regulatory approval process for biomaterials for treating skin loss. Part 2 Epidermal and dermal replacement technologies: Enhancing skin epidermal stability
Human-derived acellular matrices for dermal replacement
Lyophilized xenogenic products for skin replacement. Part 3 Combined dermis and epidermal replacement: Cultured skin substitutes
The use of keratinocytes in combination with a dermal replacement to treat skin loss
Principles of skin regeneration
Summary: biomaterials for treating skin loss
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