Part 1 Hormones and hormone action: genetic control of hormone formation; measurement of homrones; mechanisms of action of steroid hormones that act as transcription regulatory factors; mechanism of action of hormones that act at the cell surface; pathogenesis of endocrine tumours; autoimmunity and the endocrine system. Part 2 Hypothalamus and pituitary: neuroendocrinology; the anterior pituitary; posterior pituitary and water metabolism. Part 3 Thyroid: the thyroid gland. Part 4 Adrenal: the adrenal cortex; catecholamines and the adrenal medulla; endocrine hypertension. Part 5 Reproduction: disorders of the ovaries and female reproductive tract; disorders of the testes and male reproductive tract; endocrine disorders of the breast; fertility control and its complications; sexual function and dysfunction. Part 6 Fuel homeostasis: glucose homeostasis and hypoglycemia; diabetes mellitus; eating disorders - obesity, anorexia nervosa, bulimia nervosa; disorders of the lipid metabolism - cellular and molecular mechanisms regulating plasma lipoprotein metabolism. Part 7 Mineral metabolism: hormones and disorders of mineral metabolism; metabolic bone disease; kidney stones. Part 8 Development and growth: endocrinological changes of pregnancy; endocrinology of foetal development; disorders of sexual differentiation; normal and aberrant growth; puberty and its disorders. Part 9 Polyendocrine disorders: multiple endocrine neoplasia; the immunoendocrinopathy syndromes. Part 10 Paraendocrine and neoplastic syndromes: endocrine tumours of the gastroenteropancreatic system; endocrine responsive cancer; humoural manifestations of cancer; disorders of vasodilator hormones - the carcinoid syndrome and mastocytosis.