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2015
DOI: 10.1155/2015/980310
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Is There Really Relationship between Androgenetic Alopecia and Metabolic Syndrome?

Abstract:Background. There are several studies investigating the relationship between androgenetic alopecia (AGA) and metabolic syndrome (MS) with conflicting results. Objective. We sought to investigate whether there is a relationship between AGA and MS. Methods. A case-control study including 74 male patients with AGA and 42 male controls was conducted. Age, duration of AGA, AGA onset age, anthropometric measures, body mass index, lipid parameters, fasting blood glucose, blood pressure, and presence of MS were record… Show more

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Cited by 35 publications
(25 citation statements)
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“…Although numerous studies have investigated the probable relationship between androgenetic alopecia and cardiovascular risk factors, the results are discrepant.11,16,[18][19][20] Furthermore, the true pathophysiological mechanism by which androgenetic alopecia and cardiovascular risk factors may be related has not been clearly explained. We believe that there may be certain explanations for the inconsistency observed between the results of our study and other studies that show a positive association between cardiovascular risk factors and androgenetic alopecia.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…Although numerous studies have investigated the probable relationship between androgenetic alopecia and cardiovascular risk factors, the results are discrepant.11,16,[18][19][20] Furthermore, the true pathophysiological mechanism by which androgenetic alopecia and cardiovascular risk factors may be related has not been clearly explained. We believe that there may be certain explanations for the inconsistency observed between the results of our study and other studies that show a positive association between cardiovascular risk factors and androgenetic alopecia.…”
Section: Discussionmentioning
confidence: 99%
“…However, in patients with androgenetic alopecia, mean value of systolic blood pressure was significantly higher.16 A recent study conducted by Chung and colleagues showed that early-onset androgenetic alopecia may have no significant association with certain cardiovascular risk factors such as hypertension, increased waist circumference, BMI or serum lipid levels.31 Strikingly, the findings of our study showed that patients with androgenetic alopecia may have lower BMI and waist to hip ratio as compared to healthy controls.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…A meta-analysis on a cohort of 4006 men showed a 2-fold higher risk of developing MetS in men with AGA 25 . On the contrary, other authors failed to find this association in cohorts of 116 27 , 1707 28 , 184 29 , and 120 30 men. However, Hirsso and colleagues described lower insulin-sensitivity in men with AGA 31 .…”
Section: Discussionmentioning
confidence: 80%
“…Previous studies have shown a positive association between male pattern baldness and insulin resistance, metabolic syndrome, and hypertension [9] , [10] . It has also been postulated that baldness is linked to cardiovascular disease (CVD) by mechanisms, such as hyperinsulinaemia, chronic inflammation, and increased peripheral sensitivity to androgens.…”
Section: Introductionmentioning
confidence: 89%
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