| An | Film | Rol | Note |
|---|
| 1986 | Egomania – Insel ohne Hoffnung | Sally | |
| 1986 | Zastrozzi: A Romance | Julia | miniserie TV |
| 1986 | Caravaggio | Lena | |
| 1986–1990 | The Open Universe | Carla | |
| 1987 | Aria | Young Girl | |
| 1987 | Friendship's Death | Friendship | |
| 1988 | Last of England, TheThe Last of England | | |
| 1988 | Cycling the Frame | The Cyclist | Short |
| 1988 | Das Andere Ende der Welt | | |
| 1988 | Degrees of Blindness | | |
| 1988 | L' Ispirazione | | Short |
| 1989 | Play Me Something | Hairdresser | |
| 1989 | War Requiem | Nurse | |
| 1990 | Your Cheatin' Heart | Cissie Crouch | TV series (6 episodes) |
| 1990 | Garden, TheThe Garden | Madonna | |
| 1991 | Edward II | Isabella | |
| 1991 | Party - Nature Morte, TheThe Party - Nature Morte | Queenie | |
| 1992 | Shakespeare: The Animated Tales | Ophelia (voice) | TV miniseries |
| 1992 | Orlando | Orlando | |
| 1992 | Screenplay | Ella/Max Gericke | TV series (1 episode: "Man to Man") |
| 1993 | Blue | | Voice |
| 1993 | Wittgenstein | Lady Ottoline Morrell | |
| 1994 | Remembrance of Things Fast: True Stories Visual Lies | | |
| 1994 | Visions of Heaven and Hell | Narrator | TV series |
| 1996 | Female Perversions | Eve Stephens | |
| 1997 | Conceiving Ada | Ada Augusta Byron King, Countess of Lovelace | |
| 1998 | Love Is the Devil: Study for a Portrait of Francis Bacon | Muriel Belcher | |
| 1998 | Protagonists, TheThe Protagonists | Actress | |
| 1998 | Herlizeares | Diera | |
| 1999 | War Zone, TheThe War Zone | Mum | |
| 2000 | Possible Worlds | Joyce | |
| 2000 | Beach, TheThe Beach | Sal | |
| 2001 | Vanilla Sky | Rebecca Dearborn | |
| 2001 | Deep End, TheThe Deep End | Margaret Hall | |
| 2002 | Adaptation | Valerie Thomas | |
| 2002 | Teknolust | Rosetta/Ruby/Marinne/Olive | |
| 2003 | Statement, TheThe Statement | Annemarie Livi | |
| 2003 | Young Adam | Ella Gault | |
| 2005 | Constantine | Gabriel | |
| 2005 | Chronicles of Narnia: The Lion, the Witch and the Wardrobe, TheThe Chronicles of Narnia: The Lion, the Witch and the Wardrobe | Jadis, the White Witch | |
| 2005 | The Somme | Narrator | TV movie |
| 2005 | Absent Presence | Operator | Short |
| 2005 | Broken Flowers | Penny | |
| 2005 | Thumbsucker | Audrey Cobb | |
| 2006 | Stephanie Daley | Lydie Crane | |
| 2006 | Galápagos | Narrator | BBC Documentary |
| 2007 | Sleepwalkers | Violinist | Short |
| 2007 | Strange Culture | Hope Kurtz | Documentar |
| 2007 | Faceless | | Voice |
| 2007 | Man from London, TheThe Man from London | Camélia | |
| 2007 | Michael Clayton | Karen Crowder | |
| 2008 | Julia | Julia | |
| 2008 | Chronicles of Narnia: Prince Caspian, TheThe Chronicles of Narnia: Prince Caspian | Jadis, the White Witch; Centaur | Cameo[13] |
| 2008 | Burn After Reading | Katie Cox | |
| 2008 | Curious Case of Benjamin Button, TheThe Curious Case of Benjamin Button | Elizabeth Abbott | |
| 2009 | Limits of Control, TheThe Limits of Control | Blonde | |
| 2009 | The Invisible Frame | The Cyclist | |
| 2009 | I Am Love | Emma Recchi | |
| 2010 | Chronicles of Narnia: The Voyage of the Dawn Treader, TheThe Chronicles of Narnia: The Voyage of the Dawn Treader | Jadis, the White Witch | |
| 2011 | We Need to Talk About Kevin | Eva Khatchadourian | |
| 2011 | Genevieve Goes Boating | Narrator | Video short |
| 2012 | Moonrise Kingdom | Social Services | |
| 2013 | The Stars (Are Out Tonight) | | Cameo |
| 2013 | The Next Day | | Cameo |
| 2013 | Only Lovers Left Alive | Eve | |
| 2013 | Snowpiercer | Mason | |
| 2013 | The Zero Theorem | Dr Shrink-Rom | |
| 2014 | The Grand Budapest Hotel | Madame D. | |
| 2019 | The Dead Don't Die | Zelda Winston | |