- Erasmus MC: University Medical Center Rotterdam/
- Dissertation
A. Maassen van den Brink (Antoinette)
1999-12-22
Coronary Side Effects of Antimigraine Drugs From Patient to Receptor
Publication
Publication
Coronaire bijwerkingen van antimigraine geneesmiddelen: van patient tot receptor
Migraine is a paroxysmal neurological disorder, which occurs in 6% of males and15-18% of females, with the highest prevalence between the ages of 25 and 55years1,2. Attacks consist of moderate or severe headache, associated with nausea,vomiting, photo- and phonophobia3. The headache lasts 4 to 72 hours and increaseswith physical activity. The migraine attack may be resolved by sleep during or afterthe headache4. In about 15% of patients (migraine with aura), an aura may precedethe migraine headache within about one hour. The aura usually consists of visualsymptoms such as fortifications, scotoma or hemianopsia, but may also be sensory(paresthesia), motor- (weakness, paresis) or speech-related (dysarthria, aphasia)1.To study migraine scientifically, there is a clear need for uniform criteria todetermine whether a patient is suffering from a migraine headache. In 1988, theInternational Headache Society (IHS) provided such criteria5 (see Table 1.1 formigraine without and with aura).
| Additional Metadata | |
|---|---|
| Keywords | antimigraine drugs,pharmacology |
| Sponsor | Financial support by the Netherlands Heart Foundation and the Dr. Saal vanZwanenbergstichting for the publication of this thesis is gratefully acknowledged.Financial support of the following institutions and companies is gratefullyacknowledged:Anglo-Dutch Migraine Association, AstraZeneca, Centre Recherche Pierre Fabre,Glaxo Wellcome Inc., Institut de Recherches Internationales Servier,Janssen-Cilag B.V., Merck Sharpe & Dohme B.V., Novartis Pharma A.G., Pfizer Ltd.,Vanguard Medica Ltd. |
| Promotor | P.R. Saxena (Pramod Ranjan) |
| Publisher | Erasmus University Rotterdam |
| ISBN | 978-90-90-13290-7 |
| Persistent URL | hdl.handle.net/1765/16171 |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
| Citation | Maassen van den Brink, A. (1999, December 22).Coronary Side Effects of Antimigraine Drugs From Patient to Receptor. Retrieved from http://hdl.handle.net/1765/16171 |
