Clinical Trial
doi: 10.1002/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8.Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
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- PMID:9921604
- DOI: 10.1002/(sici)1097-0258(19981230)17:24<2815::aid-sim110>3.0.co;2-8
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Clinical Trial
Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
M K Parmar et al. Stat Med..
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Erratum in
- Stat Med. 2004 Jun 15;23(11):1817
Abstract
Meta-analyses aim to provide a full and comprehensive summary of related studies which have addressed a similar question. When the studies involve time to event (survival-type) data the most appropriate statistics to use are the log hazard ratio and its variance. However, these are not always explicitly presented for each study. In this paper a number of methods of extracting estimates of these statistics in a variety of situations are presented. Use of these methods should improve the efficiency and reliability of meta-analyses of the published literature with survival-type endpoints.
Comment in
- Phase III trial of concurrent thoracic radiotherapy with either first- or third-cycle chemotherapy for limited-disease small-cell lung cancer.Lueza B, Le Péchoux C, Pignon JP.Lueza B, et al.Ann Oncol. 2014 Sep;25(9):1865-1866. doi: 10.1093/annonc/mdu221. Epub 2014 Jun 11.Ann Oncol. 2014.PMID:24920790No abstract available.
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