Pediatric primary benign cardiac tumors: a 15-year review
- PMID:9424072
- DOI: 10.1016/s0002-8703(97)70032-2
Pediatric primary benign cardiac tumors: a 15-year review
Abstract
An increase in the incidence of primary cardiac tumors has been reported since the development or enhancement of noninvasive imaging modalities. We identified 56 children with primary cardiac tumors. Forty-four (78%) children had rhabdomyomas, 6 (11%) fibromas, 1 (2%) pericardial teratoma, 1 (2%) epicardial lipoma, 1 (2%) multicystic hamartoma, and 3 (5%) unspecified tumors. The mean age at diagnosis was 19 +/- 35 months (median 4.7 months, range 0.03 to 204 months), excluding 12 patients who were given the diagnosis before birth. Among 27,640 patients assessed for cardiac disease, the incidence of tumors was 0.06% (1980 to 1984), 0.22% (1985 to 1989), and 0.32% (1990 to 1995). Diagnosis was made in 55 of 56 patients by echocardiography. Catheterization was performed in five patients and magnetic resonance imaging in nine. No tumor-related deaths occurred. Nine patients had surgery because of hemodynamically significant obstruction or arrhythmias. Partial or complete regression occurred in 24 (54%) of 44 patients with rhabdomyomas. Overall, the prognosis was excellent. Individualized surgery allowed early safe treatment of symptomatic tumors.
Similar articles
- Cardiac rhabdomyoma in intrauterine life: clinical features and natural history. A case series and review of published reports.Pipitone S, Mongiovì M, Grillo R, Gagliano S, Sperandeo V.Pipitone S, et al.Ital Heart J. 2002 Jan;3(1):48-52.Ital Heart J. 2002.PMID:11899590Review.
- Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia.Miyake CY, Del Nido PJ, Alexander ME, Cecchin F, Berul CI, Triedman JK, Geva T, Walsh EP.Miyake CY, et al.J Am Coll Cardiol. 2011 Oct 25;58(18):1903-9. doi: 10.1016/j.jacc.2011.08.005.J Am Coll Cardiol. 2011.PMID:22018302
- Identification and clinical course of 166 pediatric cardiac tumors.Shi L, Wu L, Fang H, Han B, Yang J, Ma X, Liu F, Zhang Y, Xiao T, Huang M, Huang M.Shi L, et al.Eur J Pediatr. 2017 Feb;176(2):253-260. doi: 10.1007/s00431-016-2833-4. Epub 2017 Jan 10.Eur J Pediatr. 2017.PMID:28074279
- Medical and surgical management of primary cardiac tumours in infants and children.Padalino MA, Reffo E, Cerutti A, Favero V, Biffanti R, Vida V, Stellin G, Milanesi O.Padalino MA, et al.Cardiol Young. 2014 Apr;24(2):268-74. doi: 10.1017/S104795111300022X. Epub 2013 Mar 5.Cardiol Young. 2014.PMID:23462142
- Cardiac tumors. Clinical spectrum and prognosis of lesions other than classical benign myxoma in 20 patients.Reece IJ, Cooley DA, Frazier OH, Hallman GL, Powers PL, Montero CG.Reece IJ, et al.J Thorac Cardiovasc Surg. 1984 Sep;88(3):439-46.J Thorac Cardiovasc Surg. 1984.PMID:6381889Review.
Cited by
- Role of magnetic resonance imaging for evaluation of tumors in the cardiac region.Kaminaga T, Takeshita T, Kimura I.Kaminaga T, et al.Eur Radiol. 2003 Dec;13 Suppl 6:L1-10. doi: 10.1007/s00330-002-1789-0. Epub 2003 Jan 18.Eur Radiol. 2003.PMID:16440217
- Postnatal growth of rhabdomyoma prior to tumor regression.Whiteside W, Saba Z, Kurio G.Whiteside W, et al.Pediatr Cardiol. 2010 May;31(4):541-4. doi: 10.1007/s00246-009-9619-7. Epub 2010 Jan 3.Pediatr Cardiol. 2010.PMID:20047026
- Treatment strategies for pediatric patients with primary cardiac and pericardial tumors: a 30-year review.Günther T, Schreiber C, Noebauer C, Eicken A, Lange R.Günther T, et al.Pediatr Cardiol. 2008 Nov;29(6):1071-6. doi: 10.1007/s00246-008-9256-6. Epub 2008 Jul 4.Pediatr Cardiol. 2008.PMID:18600370
- Cardiac masses, part 2: key imaging features for diagnosis and surgical planning.Buckley O, Madan R, Kwong R, Rybicki FJ, Hunsaker A.Buckley O, et al.AJR Am J Roentgenol. 2011 Nov;197(5):W842-51. doi: 10.2214/AJR.11.6903.AJR Am J Roentgenol. 2011.PMID:22021531Free PMC article.Review.
- Cardiovascular manifestations of tuberous sclerosis complex and summary of the revised diagnostic criteria and surveillance and management recommendations from the International Tuberous Sclerosis Consensus Group.Hinton RB, Prakash A, Romp RL, Krueger DA, Knilans TK; International Tuberous Sclerosis Consensus Group.Hinton RB, et al.J Am Heart Assoc. 2014 Nov 25;3(6):e001493. doi: 10.1161/JAHA.114.001493.J Am Heart Assoc. 2014.PMID:25424575Free PMC article.Review.No abstract available.
MeSH terms
Related information
LinkOut - more resources
Full Text Sources