Receptor signalling and the regulation of endocytic membrane transport
- PMID:8791448
- DOI: 10.1016/s0955-0674(96)80034-2
Receptor signalling and the regulation of endocytic membrane transport
Abstract
Vesicle-mediated membrane traffic has long been considered to be a constitutive process that is not burdened by layers of regulation. This contrasts with transmembrane signalling systems at the plasma membrane which relay information (i.e. extracellular stimuli) from the cell surface to the cytoplasm via a myriad of different protein-protein interactions and second messenger cascades. An accumulation of recent evidence, however, now suggests that signal-transduction pathways also play a critical role in the regulation of protein and membrane trafficking. In particular, the analysis of the signalling pathways initiated by receptor tyrosine kinases at the plasma membrane has yielded new insights into the molecular mechanisms of endocytosis. In addition, recent evidence has suggested potential new roles for two previously characterized vesicle coat proteins in a membrane traffic route that is regulated via cell surface receptor signalling.
Similar articles
- Lipid kinases play crucial and multiple roles in membrane trafficking and signaling.Heath CM, Stahl PD, Barbieri MA.Heath CM, et al.Histol Histopathol. 2003 Jul;18(3):989-98. doi: 10.14670/HH-18.989.Histol Histopathol. 2003.PMID:12792909Review.
- Ubiquitin in trafficking: the network at work.Acconcia F, Sigismund S, Polo S.Acconcia F, et al.Exp Cell Res. 2009 May 15;315(9):1610-8. doi: 10.1016/j.yexcr.2008.10.014. Epub 2008 Oct 28.Exp Cell Res. 2009.PMID:19007773Review.
- Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking.Fraser J, Cabodevilla AG, Simpson J, Gammoh N.Fraser J, et al.Essays Biochem. 2017 Dec 12;61(6):597-607. doi: 10.1042/EBC20170091. Print 2017 Dec 12.Essays Biochem. 2017.PMID:29233871Free PMC article.Review.
- TRP Channel Trafficking.Planells-Cases R, Ferrer-Montiel A.Planells-Cases R, et al.In: Liedtke WB, Heller S, editors. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 23.In: Liedtke WB, Heller S, editors. TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. Boca Raton (FL): CRC Press/Taylor & Francis; 2007. Chapter 23.PMID:21204515Free Books & Documents.Review.
- Intracellular trafficking of hormone receptors.Gáborik Z, Hunyady L.Gáborik Z, et al.Trends Endocrinol Metab. 2004 Aug;15(6):286-93. doi: 10.1016/j.tem.2004.06.009.Trends Endocrinol Metab. 2004.PMID:15358282Review.
Cited by
- Transduction of basolateral-to-apical signals across epithelial cells: ligand-stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals.Luton F, Mostov KE.Luton F, et al.Mol Biol Cell. 1999 May;10(5):1409-27. doi: 10.1091/mbc.10.5.1409.Mol Biol Cell. 1999.PMID:10233153Free PMC article.
- Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes.Vickery RG, von Zastrow M.Vickery RG, et al.J Cell Biol. 1999 Jan 11;144(1):31-43. doi: 10.1083/jcb.144.1.31.J Cell Biol. 1999.PMID:9885242Free PMC article.
- Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders.Placci M, Giannotti MI, Muro S.Placci M, et al.Adv Drug Deliv Rev. 2023 Jun;197:114683. doi: 10.1016/j.addr.2022.114683. Epub 2023 Jan 16.Adv Drug Deliv Rev. 2023.PMID:36657645Free PMC article.Review.
- The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.Ringstad N, Nemoto Y, De Camilli P.Ringstad N, et al.Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8569-74. doi: 10.1073/pnas.94.16.8569.Proc Natl Acad Sci U S A. 1997.PMID:9238017Free PMC article.
- Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.Wu TT, Castle JD.Wu TT, et al.Mol Biol Cell. 1998 Jul;9(7):1661-74. doi: 10.1091/mbc.9.7.1661.Mol Biol Cell. 1998.PMID:9658162Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources