Review
doi: 10.1007/BF00871944.Regulatory circuits of the amdS gene of Aspergillus nidulans
Affiliations
- PMID:7847883
- DOI: 10.1007/BF00871944
Item in Clipboard
Review
Regulatory circuits of the amdS gene of Aspergillus nidulans
M J Hynes. Antonie Van Leeuwenhoek.1994.
Display options
Format
Display options
Format
Abstract
The amdS gene codes for an acetamidase enzyme that hydrolyses acetamide to acetate and ammonium thus providing A. nidulans with a source of carbon and nitrogen. The exceptionally favourable genetics of this system combined with molecular analysis have enabled many regulatory circuits affecting amdS to be identified genetically. Characterization of the regulatory genes and the definition of the cis-acting sites involved have been done using both in vivo and in vitro mutagenesis. Recent results on the analysis of the system are presented.
Similar articles
- Cloning and molecular characterization of the acetamidase-encoding gene (amdS) from Aspergillus oryzae.Gomi K, Kitamoto K, Kumagai C.Gomi K, et al.Gene. 1991 Dec 1;108(1):91-8. doi: 10.1016/0378-1119(91)90491-s.Gene. 1991.PMID:1840550
- A mutation affecting amdS expression in Aspergillus nidulans contains a triplication of a cis-acting regulatory sequence.Katz ME, Saleeba JA, Sapats SI, Hynes MJ.Katz ME, et al.Mol Gen Genet. 1990 Feb;220(3):373-6. doi: 10.1007/BF00391741.Mol Gen Genet. 1990.PMID:2187153
- Multiple copies of the amdS gene of Aspergillus nidulans cause titration of trans-acting regulatory proteins.Kelly JM, Hynes MJ.Kelly JM, et al.Curr Genet. 1987;12(1):21-31. doi: 10.1007/BF00420723.Curr Genet. 1987.PMID:2835171
- Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans.Davis MA, Kelly JM, Hynes MJ.Davis MA, et al.Genetica. 1993;90(2-3):133-45. doi: 10.1007/BF01435035.Genetica. 1993.PMID:8119589Review.
- Regulatory genes in Aspergillus nidulans.Davis MA, Hynes MJ.Davis MA, et al.Trends Genet. 1989 Jan;5(1):14-9. doi: 10.1016/0168-9525(89)90006-1.Trends Genet. 1989.PMID:2652389Review.
Cited by
- Identification of a Yarrowia lipolytica acetamidase and its use as a yeast genetic marker.Hamilton M, Consiglio AL, MacEwen K, Shaw AJ, Tsakraklides V.Hamilton M, et al.Microb Cell Fact. 2020 Feb 5;19(1):22. doi: 10.1186/s12934-020-1292-9.Microb Cell Fact. 2020.PMID:32024536Free PMC article.
- Differential expression of Aspergillus nidulans ammonium permease genes is regulated by GATA transcription factor AreA.Monahan BJ, Askin MC, Hynes MJ, Davis MA.Monahan BJ, et al.Eukaryot Cell. 2006 Feb;5(2):226-37. doi: 10.1128/EC.5.2.226-237.2006.Eukaryot Cell. 2006.PMID:16467464Free PMC article.
- amdSYM, a new dominant recyclable marker cassette for Saccharomyces cerevisiae.Solis-Escalante D, Kuijpers NG, Bongaerts N, Bolat I, Bosman L, Pronk JT, Daran JM, Daran-Lapujade P.Solis-Escalante D, et al.FEMS Yeast Res. 2013 Feb;13(1):126-39. doi: 10.1111/1567-1364.12024. Epub 2012 Dec 17.FEMS Yeast Res. 2013.PMID:23253382Free PMC article.
- The role of the GATA transcription factor AreB in regulation of nitrogen and carbon metabolism in Aspergillus nidulans.Chudzicka-Ormaniec P, Macios M, Koper M, Weedall GD, Caddick MX, Weglenski P, Dzikowska A.Chudzicka-Ormaniec P, et al.FEMS Microbiol Lett. 2019 Mar 1;366(6):fnz066. doi: 10.1093/femsle/fnz066.FEMS Microbiol Lett. 2019.PMID:30939206Free PMC article.
- Nitrogen Metabolism and Growth Enhancement in Tomato Plants Challenged with Trichoderma harzianum Expressing the Aspergillus nidulans Acetamidase amdS Gene.Domínguez S, Rubio MB, Cardoza RE, Gutiérrez S, Nicolás C, Bettiol W, Hermosa R, Monte E.Domínguez S, et al.Front Microbiol. 2016 Aug 3;7:1182. doi: 10.3389/fmicb.2016.01182. eCollection 2016.Front Microbiol. 2016.PMID:27536277Free PMC article.