doi: 10.1126/science.165.3897.1023.
Infection as the etiology of spongiform encephalopathy (Creutzfeldt-Jakob disease)
- PMID:5804726
- DOI: 10.1126/science.165.3897.1023
Item in Clipboard
Infection as the etiology of spongiform encephalopathy (Creutzfeldt-Jakob disease)
C J Gibbs Jr et al. Science..
Display options
Format
Display options
Format
Abstract
Fatal spongiform encephalopathy occurred in four chimpanzees 12 to 14 months after inoculation with suspensions of brain from four patients, respectively. Chimpanzee to chimpanzee transmission was effected without reduction in incubation period. Retransmission of the disease to a second chimpanzee occurred when an inoculum that had been stored at -70 degrees C for over 2 years was used.
Similar articles
- Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee.Gibbs CJ Jr, Gajdusek DC, Asher DM, Alpers MP, Beck E, Daniel PM, Matthews WB.Gibbs CJ Jr, et al.Science. 1968 Jul 26;161(3839):388-9. doi: 10.1126/science.161.3839.388.Science. 1968.PMID:5661299
- Experimental spongiform encephalopathy (Creutzfeldt-Jakob disease) in chimpanzees. Electron microscopic studies.Lampert PW, Gajdusek DC, Gibbs CJ Jr.Lampert PW, et al.J Neuropathol Exp Neurol. 1971 Jan;30(1):20-32. doi: 10.1097/00005072-197101000-00004.J Neuropathol Exp Neurol. 1971.PMID:4925307No abstract available.
- Jakob-Creutzfeldt syndrome: an infectious disease?[No authors listed][No authors listed]Br Med J. 1969 Mar 1;1(5643):528-9. doi: 10.1136/bmj.1.5643.528.Br Med J. 1969.PMID:5764697Free PMC article.No abstract available.
- Neuropathological findings in new variant CJD and experimental transmission of BSE.Ironside JW.Ironside JW.FEMS Immunol Med Microbiol. 1998 Jun;21(2):91-5. doi: 10.1111/j.1574-695X.1998.tb01153.x.FEMS Immunol Med Microbiol. 1998.PMID:9684997Review.
- Experimental interspecies transmission studies of the transmissible spongiform encephalopathies to cattle: comparison to bovine spongiform encephalopathy in cattle.Hamir AN, Kehrli ME Jr, Kunkle RA, Greenlee JJ, Nicholson EM, Richt JA, Miller JM, Cutlip RC.Hamir AN, et al.J Vet Diagn Invest. 2011 May;23(3):407-20. doi: 10.1177/1040638711403404.J Vet Diagn Invest. 2011.PMID:21908269Review.
Cited by
- On the biology of prions.Prusiner SB, Gabizon R, McKinley MP.Prusiner SB, et al.Acta Neuropathol. 1987;72(4):299-314. doi: 10.1007/BF00687261.Acta Neuropathol. 1987.PMID:3554880Review.
- Prions in Saccharomyces and Podospora spp.: protein-based inheritance.Wickner RB, Taylor KL, Edskes HK, Maddelein ML, Moriyama H, Roberts BT.Wickner RB, et al.Microbiol Mol Biol Rev. 1999 Dec;63(4):844-61, table of contents. doi: 10.1128/MMBR.63.4.844-861.1999.Microbiol Mol Biol Rev. 1999.PMID:10585968Free PMC article.Review.
- Slow virus infection of nervous tissue.Lampert P.Lampert P.Calif Med. 1971 May;114(5):75.Calif Med. 1971.PMID:18730518Free PMC article.No abstract available.
- The significance of cyclic EEG changes in Creutzfeldt-Jakob disease: prognostic value of their course in 9 patients.Terzano MG, Mancia D, Zacchetti O, Manzoni GC.Terzano MG, et al.Ital J Neurol Sci. 1981 Aug;2(3):243-54. doi: 10.1007/BF02335404.Ital J Neurol Sci. 1981.PMID:7042644
- Transmissible slow diseases.Hartigan PJ.Hartigan PJ.Ir J Med Sci. 1973 Jan;142(1):27-34. doi: 10.1007/BF02949986.Ir J Med Sci. 1973.PMID:4733360No abstract available.
MeSH terms
Related information
LinkOut - more resources
Full Text Sources