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.1970 Oct;104(1):313-22.
doi: 10.1128/jb.104.1.313-322.1970.

Cellular control of the synthesis and activity of the bacterial luminescent system

Cellular control of the synthesis and activity of the bacterial luminescent system

K H Nealson et al. J Bacteriol.1970 Oct.

Abstract

In bioluminescent bacteria growing in shake flasks, the enzyme luciferase has been shown to be synthesized in a relatively short burst during the period of exponential growth. The luciferase gene appears to be completely inactive in a freshly inoculated culture; the pulse of preferential luciferase synthesis which occurs later is the consequence of its activation at the level of deoxyribonucleic acid transcription which is attributed to an effect of a "conditioning" of the medium by the growing of cells. Although cells grown in a minimal medium also exhibit a similar burst of synthesis of the luminescent system, the amount of synthesis is quantitatively less, relative to cell mass. Under such conditions, added arginine results in a striking stimulation of bioluminescence. This is attributed to a stimulation of existing patterns of synthesis and not to induction or derepression per se.

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References

    1. J Bacteriol. 1967 Nov;94(5):1638-47 - PubMed
    1. J Bacteriol. 1968 Mar;95(3):975-9 - PubMed
    1. Biochemistry. 1969 Dec;8(12):4681-9 - PubMed
    1. J Cell Physiol. 1950 Oct;36(2):165-83 - PubMed
    1. J Immunol. 1959 Feb;82(2):153-60 - PubMed

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